Search Results - "Hørby Christensen, Alex"

Dilated cardiomyopathy caused by truncating titin variants: long-term outcomes, arrhythmias, response to treatment and sex differences by Vissing, Christoffer Rasmus, Rasmussen, Torsten Bloch, Dybro, Anne Mette, Olesen, Morten Salling, Pedersen, Lisbeth Nørum, Jensen, Morten, Bundgaard, Henning, Christensen, Alex Hørby

“…Truncating variants in titin (TTNtv) are the most common cause of dilated cardiomyopathy (DCM). We evaluated the genotype-phenotype correlation in TTNtv-DCM,…”
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Plantar keratoderma and curly hair as a diagnostic clue of cardiomyopathy risk by Gram, Stine Bjørn, Brusgaard, Klaus, Bygum, Anette, Christensen, Alex Hørby, Ousager, Lilian Bomme

“…A 17-year-old woman visited the dermatology clinic due to thickened and painful skin on her soles since early childhood. Physical examination showed remarkable…”
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Aortic dissection in a young male with persistent ductus arteriosus and a novel variant in MYLK by Boelman, Maria Bejerholm, Hansen, Thomas van Overeem, Smith, Matthias Nybro, Hammer‐Hansen, Sophia, Christensen, Alex Hørby, Diness, Birgitte Rode

“…Pathogenic variants in several genes involved in the function or regulation of smooth muscle cells (SMC) are known to predispose to congenital heart disease…”
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Loss of Nuclear Envelope Integrity and Increased Oxidant Production Cause DNA Damage in Adult Hearts Deficient in PKP2: A Molecular Substrate of ARVC by Pérez-Hernández, Marta, van Opbergen, Chantal J.M., Bagwan, Navratan, Vissing, Christoffer Rasmus, Marrón-Liñares, Grecia M., Zhang, Mingliang, Torres Vega, Estefania, Sorrentino, Andrea, Drici, Lylia, Sulek, Karolina, Zhai, Ruxu, Hansen, Finn B., Christensen, Alex Hørby, Boesgaard, Søren, Gustafsson, Finn, Rossing, Kasper, Small, Eric M., Davies, Michael J., Rothenberg, Eli, Sato, Priscila Y., Cerrone, Marina, Jensen, Thomas Hartvig Lindkær, Qvortrup, Klaus, Bundgaard, Henning, Delmar, Mario, Lundby, Alicia

“…Arrhythmogenic right ventricular cardiomyopathy (ARVC) is characterized by high propensity to life-threatening arrhythmias and progressive loss of heart…”
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Understanding the incidence of atrial fibrillation and stroke in hypertrophic cardiomyopathy patients: insights from Danish nationwide registries by Zörner, Christopher R, Schjerning, Anne-Marie, Jensen, Morten Kvistholm, Christensen, Alex Hørby, Tfelt-Hansen, Jacob, Tønnesen, Jacob, Riis-Vestergaard, Lise Da, Middelfart, Charlotte, Rasmussen, Peter Vibe, Gislason, Gunnar, Hansen, Morten Lock

“…Abstract Aims The treatment of atrial fibrillation (AF) in hypertrophic cardiomyopathy (HCM) can be challenging since AF aggravates symptoms and increases the…”
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Genotype-phenotype correlation in arrhythmogenic right ventricular cardiomyopathy-risk of arrhythmias and heart failure by Christensen, Alex Hørby, Platonov, Pyotr G, Jensen, Henrik Kjærulf, Chivulescu, Monica, Svensson, Anneli, Dahlberg, Pia, Madsen, Trine, Frederiksen, Tanja Charlotte, Heliö, Tiina, Lie, Øyvind Haugen, Haugaa, Kristina H, Hastrup Svendsen, Jesper, Bundgaard, Henning

“…Arrhythmogenic right ventricular cardiomyopathy (ARVC) is predominantly caused by desmosomal genetic variants, and clinical hallmarks include arrhythmias and…”
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Cardiac findings in newborn twins by Molin, Julie, Pærregaard, Maria Munk, Pihl, Christian, Thygesen, Caroline Boye, Pietersen, Adrian, Dannesbo, Sofie, Norsk, Jakob Boesgaard, Raja, Anna Axelsson, Vøgg, Ruth Ottilia B., Sillesen, Anne‐Sophie, Iversen, Kasper Karmark, Bundgaard, Henning, Christensen, Alex Hørby

“…Aims To evaluate cardiac findings in newborn twins from the general population and investigate if newborn twins may require systematic evaluation of cardiac…”
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Non-diagnostic autopsy findings in sudden unexplained death victims by Yazdanfard, Puriya Daniel, Christensen, Alex Hørby, Tfelt-Hansen, Jacob, Bundgaard, Henning, Winkel, Bo Gregers

“…Several inherited cardiac diseases may lead to sudden cardiac death (SCD) a devastating event in the families. It is crucial to establish a post mortem…”
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Natural Course of Electrocardiographic Features in Arrhythmogenic Right Ventricular Cardiomyopathy and Their Relation to Ventricular Arrhythmic Events by Svensson, Anneli, Jensen, Henrik Kjaerulf, Boonstra, Machteld J, Tétreault-Langlois, Marianne, Dahlberg, Pia, Bundgaard, Henning, Christensen, Alex Hørby, Rylance, Rebecca T, Svendsen, Jesper H, Cadrin-Tourigny, Julia, Te Riele, Anneline S J M, Platonov, Pyotr G

“…Electrocardiographic abnormalities are common in arrhythmogenic right ventricular cardiomyopathy and are included in the 2010 Task Force Criteria. Their time…”
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Effect of moderate potassium-elevating treatment in long QT syndrome: the TriQarr Potassium Study by Marstrand, Peter, Almatlouh, Kasim, Kanters, Jørgen K, Graff, Claus, Christensen, Alex Hørby, Bundgaard, Henning, Theilade, Juliane

“…BackgroundIn long QT syndrome (LQTS), beta blockers prevent arrhythmias. As a supplement, means to increase potassium has been suggested. We set to investigate…”
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Reassessment of Gene-Elusive Familial Dilated Cardiomyopathy Leading to the Discovery of a Homozygous AARS2 Variant—The Importance of Regular Reassessment of Genetic Findings by Bhardwaj, Priya, Vissing, Christoffer Rasmus, Stampe, Niels Kjær, Rossing, Kasper, Christensen, Alex Hørby, Jensen, Thomas Hartvig Lindkær, Winkel, Bo Gregers

“…Background: AARS2 encodes the mitochondrial protein alanyl-tRNA synthetase 2 (MT-AlaRS), an important enzyme in oxidative phosphorylation. Variants in AARS2…”
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The Neonatal QRS Complex and Its Association with Left Ventricular Mass by Molin, Julie, Christensen, Alex Hørby

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Gestational Age and Neonatal Electrocardiograms by Hartmann, Joachim, Pærregaard, Maria Munk, Norsk, Jakob, Pietersen, Adrian, Iversen, Kasper Karmark, Bundgaard, Henning, Christensen, Alex Hørby

“…Interpretation of the neonatal electrocardiogram (ECG) is challenging due to the profound changes of the cardiovascular system in this period. We aimed to…”
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Cardiotoxicity in metastatic melanoma patients treated with BRAF and MEK inhibitors in a real-world setting by Pedersen, Sidsel, Larsen, Kirstine Ostenfeld, Christensen, Alex Hørby, Svane, Inge Marie, Zerahn, Bo, Ellebaek, Eva

“…Combination therapy with BRAF and MEK inhibitors (BRAF/MEKi) has significantly improved the outcome for patients with BRAF-mutated melanoma. A reduction in…”
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Myocarditis Mimicking Arrhythmogenic Right Ventricular Cardiomyopathy by Christensen, Alex Hørby, MD, Svendsen, Jesper Hastrup, MD

“…Voltage-guided biopsy is an elegant way of obtaining histological material from areas of the right ventricle with electrical signs of regional abnormalities…”
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CineECG analysis provides new insights into Familial ST-segment Depression Syndrome by Frosted, Rasmus, Paludan-Müller, Christian, Vad, Oliver Bundgaard, Olesen, Morten Salling, Bundgaard, Henning, van Dam, Peter, Christensen, Alex Hørby

“…Abstract Aims Familial ST-segment Depression Syndrome (Fam-STD) is a novel inherited cardiac disease associated with arrhythmias and sudden cardiac death. This…”
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Natural history of cardiac involvement in myotonic dystrophy type 1 – Emphasis on the need for lifelong follow-up by Petri, Helle, Mohammad, Batool J.Y., Kristensen, Andreas Torp, Thune, Jens Jakob, Vissing, John, Køber, Lars, Witting, Nanna, Bundgaard, Henning, Christensen, Alex Hørby

“…Cardiac involvement represents a major cause of morbidity and mortality in patients with myotonic dystrophy type 1 (DM1) and prevention of sudden cardiac death…”
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Family Screening in Hypertrophic Cardiomyopathy: Identification of Relatives With Low Yield From Systematic Follow-Up by Silajdzija, Elvira, Rasmus Vissing, Christoffer, Basse Christensen, Emma, Lamiokor Mills, Helen, Olivia Kock, Thilde, Andersen, Lars Juel, Snoer, Martin, Thune, Jens Jakob, Daniel Bartels, Emil, Axelsson Raja, Anna, Hørby Christensen, Alex, Bundgaard, Henning

“…Hypertrophic cardiomyopathy (HCM) is a common inherited cardiac disease, and clinical and genetic family screening is recommended by guidelines. This study…”
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Cardiogenetic screening amongst families of sudden cardiac death victims: Authors' reply by Hansen, Benjamin Lautrup, Winkel, Bo Gregers, Bundgaard, Henning, Christensen, Alex Hørby

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Diagnostic yield in victims of sudden cardiac death and their relatives by Hansen, Benjamin Lautrup, Jacobsen, Elisabeth Mütze, Kjerrumgaard, Amalie, Tfelt-Hansen, Jacob, Winkel, Bo Gregers, Bundgaard, Henning, Christensen, Alex Hørby

“…Abstract Aims International guidelines recommend cardiogenetic screening in families with sudden cardiac death (SCD) if the suspected cause is an inherited…”
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