Search Results - "Højfeldt, Jonas Westergaard"
-
1
Molecular Mechanisms Directing PRC2 Recruitment and H3K27 Methylation
Published in Molecular cell (04-04-2019)“…The polycomb repressive complex 2 (PRC2) is a chromatin-associated methyltransferase catalyzing mono-, di-, and trimethylation of lysine 27 on histone H3…”
Get full text
Journal Article -
2
Role of the Polycomb Repressive Complex 2 (PRC2) in Transcriptional Regulation and Cancer
Published in Cold Spring Harbor perspectives in medicine (01-09-2016)“…The chromatin environment is modulated by a machinery of chromatin modifiers, required for the specification and maintenance of cell fate. Many mutations in…”
Get full text
Journal Article -
3
Non-core Subunits of the PRC2 Complex Are Collectively Required for Its Target-Site Specificity
Published in Molecular cell (07-11-2019)“…The Polycomb repressive complex 2 (PRC2) catalyzes H3K27 methylation across the genome, which impacts transcriptional regulation and is critical for…”
Get full text
Journal Article -
4
A Yoctoliter-Scale DNA Reactor for Small-Molecule Evolution
Published in Journal of the American Chemical Society (28-01-2009)“…The center of DNA three-way junctions, constituting a yoctoliter (10−24 L) volume, is applied as an efficient reactor to create DNA-encoded libraries of…”
Get full text
Journal Article -
5
Exogenous Control of the Assembly of Transcriptional Complexes at Gene Promoters
Published 01-01-2011“…Establishment of gene expression patterns defines cellular function and the first critical step in this process is transcription. Exogenous agents that can…”
Get full text
Dissertation