Search Results - "Hörmann, Theresa R."
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In-line implementation of an image-based particle size measurement tool to monitor hot-melt extruded pellets
Published in International journal of pharmaceutics (15-05-2014)“…[Display omitted] •In-line particle size analysis during continuous hot-die face pelletizing.•Particle size measurement via stereo imaging with three different…”
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Measurement of residence time distributions and material tracking on three continuous manufacturing lines
Published in International journal of pharmaceutics (30-05-2019)“…[Display omitted] Over the recent decade, benefits of continuous manufacturing (CM) of pharmaceutical products have been acknowledged widely. In contrast to…”
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Feeding of particle-based materials in continuous solid dosage manufacturing: a material science perspective
Published in Drug discovery today (01-04-2020)“…•Continuous processing represents new challenges in pharmaceutical material science.•Critique of key process steps such as feeding on product quality has…”
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Predicting powder feedability: A workflow for assessing the risk of flow stagnation and defining the operating space for different powder-feeder combinations
Published in International journal of pharmaceutics (15-12-2022)“…[Display omitted] •Extensive material and feeder characterization for ten pharmaceutical powders and four different feeders.•First time introduction of feeder…”
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Assessment of Tribo-charging and Continuous Feeding Performance of Direct Compression Grades of Isomalt and Mannitol Powders
Published in AAPS PharmSciTech (28-03-2023)“…Tribo-charging is often a root cause of mass flow deviations and powder adhesion during continuous feeding. Thus, it may critically impact product quality. In…”
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Development of a multistep reaction cascade for the synthesis of a sacubitril precursor in continuous flow
Published in Journal of flow chemistry (01-03-2020)“…The active pharmaceutical ingredient sacubitril acts as a neprilysin inhibitor in the body and is administered to patients suffering from high blood pressure…”
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Improving Continuous Loss-in-weight Feeding Accuracy by a Novel Hopper Design
Published in Journal of pharmaceutical innovation (01-10-2024)“…Purpose Powder feeding is a vital unit operation in the continuous manufacturing of pharmaceutical products. Loss-in-weight twin-screw feeders are commonly…”
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