Search Results - "Hörl, W. H."

The Multifunctional Role of mTOR in Innate Immunity: Implications for Transplant Immunity by Säemann, M. D., Haidinger, M., Hecking, M., Hörl, W. H., Weichhart, T.

“…The mammalian target of rapamycin (mTOR) is an evolutionary conserved serine–threonine kinase that senses various environmental stimuli in most cells primarily…”
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CMV Late Phase‐Induced mTOR Activation Is Essential for Efficient Virus Replication in Polarized Human Macrophages by Poglitsch, M., Weichhart, T., Hecking, M., Werzowa, J., Katholnig, K., Antlanger, M., Krmpotic, A., Jonjic, S., Hörl, W. H., Zlabinger, G. J., Puchhammer, E., Säemann, M. D.

“…Human cytomegalovirus (CMV) remains one of the most important pathogens following solid‐organ transplantation. Mounting evidence indicates that mammalian…”
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Posttransplant HLA Alloreactivity in Stable Kidney Transplant Recipients—Incidences and Impact on Long‐Term Allograft Outcomes by Bartel, G., Regele, H., Wahrmann, M., Huttary, N., Exner, M., Hörl, W. H., Böhmig, G. A.

“…Humoral alloreactivity is well established to predict adverse allograft outcomes. However, in some recipients, alloantibodies may also occur in the absence of…”
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In Vitro Detection of C4d‐Fixing HLA Alloantibodies: Associations With Capillary C4d Deposition in Kidney Allografts by Bartel, G., Wahrmann, M., Exner, M., Regele, H., Huttary, N., Schillinger, M., Körmöczi, G. F., Hörl, W. H., Böhmig, G. A.

“…Capillary C4d deposition is a valuable marker of antibody‐mediated rejection (AMR). In this analysis, flow cytometric detection of alloantibody‐triggered C4d…”
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Pivotal Role of Complement‐Fixing HLA Alloantibodies in Presensitized Kidney Allograft Recipients by Wahrmann, M., Exner, M., Schillinger, M., Haidbauer, B., Regele, H., Körmöczi, G. F., Hörl, W. H., Böhmig, G. A.

“…Recipient presensitization represents a major risk factor for kidney allograft loss. Complement fixation may be a critical attribute of deleterious…”
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Tamm-Horsfall protein: a multilayered defence molecule against urinary tract infection by Säemann, M. D., Weichhart, T., Hörl, W. H., Zlabinger, G. J.

“…Urinary tract infection (UTI) is the most common nonepidemic bacterial infection in humans, representing a constant danger for the host. Both innate and…”
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Kidney biopsy in patients with diabetes mellitus by Haider, D G, Peric, S, Friedl, A, Fuhrmann, V, Wolzt, M, Hörl, W H, Soleiman, A

“…The clinical consequences of the results obtained by kidney biopsy in patients with diabetes mellitus Type 1 or Type 2 have been controversial. Our study was…”
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IgG immunoadsorption reduces systemic lupus erythematosus activity and proteinuria: a long term observational study by Stummvoll, G H, Aringer, M, Smolen, J S, Schmaldienst, S, Jiménez-Boj, E, Hörl, W H, Graninger, W B, Derfler, K

“…Objective: To analyse the effects of rigorous immunoglobulin removal by immunoadsorption (IAS) on proteinuria (primary outcome variable), disease activity…”
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Adequacy of automated peritoneal dialysis with and without manual daytime exchange: A randomized controlled trial by Demetriou, D., Habicht, A., Schillinger, M., Hörl, W.H., Vychytil, A.

“…Until now, it remains unclear whether the addition of manual daytime exchanges or increasing the nightly dialysate flow is the best strategy to optimize…”
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Anti‐inflammatory effects of sodium butyrate on human monocytes: potent inhibition of IL‐12 and up‐regulation of IL‐10 production by Säemann, Marcus D., Böhmig, Georg A., Österreicher, Christoph H., Burtscher, Helmut, Parolini, Ornella, Diakos, Christos, Stöckl, Johannes, Hörl, Walter H., Zlabinger, Gerhard J.

“…ABSTRACT Cytokines are critical in regulating unresponsiveness versus immunity towards enteric antigens derived from the intestinal flora and ingested food…”
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Treatment of coagulation inhibitors with extracorporeal immunoadsorption (Ig‐Therasorb) by Jansen, M., Schmaldienst, S., Banyai, S., Quehenberger, P., Pabinger, I., Derfler, K., Hörl, W. H., Knöbl, P.

“…Coagulation inhibitors may occur as alloantibodies in patients with congenital factor deficiencies or as autoantibodies in patients with a previously normal…”
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Urinary tract infection in renal transplant recipients by Säemann, M., Hörl, W. H.

“…ABSTRACT Urinary tract infection (UTI) is common in renal transplant recipients. Frequency of UTIs depend on many factors such as age, female gender, kidney…”
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Intravenous immunoglobulin application following immunoadsorption: benefit or risk in patients with autoimmune diseases? by Schmaldienst, S., Müllner, M., Goldammer, A., Spitzauer, S., Banyai, S., Hörl, W. H., Derfler, K.

“…Objective. To evaluate infection rates, side‐effects and autoantibody resynthesis after immunoadsorption with and without intravenous immunoglobulin…”
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Calcitonin concentrations in patients with chronic kidney disease and medullary thyroid carcinoma or c-cell hyperplasia by Borchhardt, K.A., Heinzl, H., Gessl, A., Hörl, W.H., Kaserer, K., Sunder-Plassmann, G.

“…It is currently not known which level of pentagastrin-stimulated calcitonin serum concentration indicates medullary thyroid carcinoma in patients with chronic…”
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Postprandial blood glucose level in maintenance hemodialysis patients predicts post-transplant-diabetes-mellitus by Haider, D G, Mittermayer, F, Friedl, A, Batrice, A, Auinger, M, Wolzt, M, Hörl, W H

“…Post-transplant-diabetes-mellitus (PTDM) is a frequent complication after kidney transplantation. One-hundred-and-seven patients with kidney transplantation…”
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Prolonged red cell aplasia after major ABO-incompatible allogeneic hematopoietic stem cell transplantation: removal of persisting isohemagglutinins with Ig-Therasorb immunoadsorption by RABITSCH, W, KNÖBL, P, PRINZ, E, KEIL, F, GREINIX, H, KALHS, P, WOREL, N, JANSEN, M, HÖRL, W. H, DERFLER, K

“…Delayed donor red cell engraftment and prolonged red cell aplasia (PRCA) are well-recognized complications of major ABO-incompatible myeloablative and…”
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Contribution of anaemia to progression of renal disease: a debate by Rossert, J. A., McClellan, W. M., Roger, S. D., Verbeelen, D. L., Hörl, W. H.

“…It is hypothesized that anaemia contributes to the progression of renal disease via hypoxia and oxidative stress. These effects may stimulate the production of…”
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Impact of parathyroidectomy on neutrophil cytosolic calcium in chronic kidney disease patients: a prospective parallel group trial by DEICHER, R., KIRSCH, B., MÜLLNER, M., KACZIREK, K., NIEDERLE, B., HÖRL, W. H.

“… Objectives.  Polymorphonuclear leucocytes (PMNs) of chronic kidney disease (CKD) patients display elevated basal cytosolic calcium concentrations (iCa2+). As…”
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How to diagnose and correct iron deficiency during r-huEPO therapy—a consensus report by HÖRL, W. H, CAVILL, I, MACDOUGALL, I. C, SCHAEFER, R. M, SUNDER-PLASSMANN, G

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Detecting prostate cancer by intracellular macrophage prostate-specific antigen (PSA): a more specific and sensitive marker than conventional serum total PSA by Herwig, R., Mitteregger, D., Djavan, B., Kramer, G., Margreiter, M., Leers, M. P., Glodny, B., Haider, D. G., Hörl, W. H., Marberger, M.

“…Background  Serum prostate‐specific antigen (PSA) is a standard method and a widely used marker for prostate cancer, but it has a poor specificity for early…”
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