Search Results - "Högger, Petra"

Stability of Dietary Polyphenols under the Cell Culture Conditions: Avoiding Erroneous Conclusions by Xiao, Jianbo, Högger, Petra

“…Most data of bioactivity from dietary polyphenols have been derived from in vitro cell culture experiments. In this context, little attention is paid to…”
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Relationship Between Amphetamine Concentrations in Saliva and Serum in Children and Adolescents With Attention-Deficit/Hyperactivity Disorder by Wohkittel, Christopher, Högger, Petra, Fekete, Stefanie, Romanos, Marcel, Gerlach, Manfred

“…Therapeutic drug monitoring (TDM) is a valid tool for the optimization of psychopharmacotherapy; however, in child and adolescent psychiatry, uncomfortable…”
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Facilitated cellular uptake and suppression of inducible nitric oxide synthase by a metabolite of maritime pine bark extract (Pycnogenol) by Uhlenhut, Klaus, Högger, Petra

“…Many natural products exhibit anti-inflammatory activity by suppressing excessive nitric oxide (NO) production by inducible NO synthase (iNOS). The maritime…”
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Review of the pharmacokinetics of French maritime pine bark extract (Pycnogenol ® ) in humans by Bayer, Jasmin, Högger, Petra

“…The French maritime pine bark extract Pycnogenol is a proprietary product from Aiton. It complies with the quality specifications in the monograph "Pine…”
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Metabolism of dietary flavonoids in liver microsomes by Xiao, Jianbo, Högger, Petra

“…Flavonoids undergo substantial hepatic metabolism and the metabolites might significantly contribute to the effects of these dietary constituents. The…”
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Human receptor kinetics and lung tissue retention of the enhanced-affinity glucocorticoid fluticasone furoate by Valotis, Anagnostis, Högger, Petra

“…Fluticasone furoate (FF)--USAN approved name, a new topically active glucocorticoid has been recently identified. The aim of this study was to characterise the…”
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Screening of Inhibitory Effects of Polyphenols on Akt-Phosphorylation in Endothelial Cells and Determination of Structure-Activity Features by Dirimanov, Stoyan, Högger, Petra

“…Polyphenols exert beneficial effects in type 2 diabetes mellitus (T2DM). However, their mechanism of action remains largely unknown. Endothelial Akt-kinase…”
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Influence of diabetes on the pharmacokinetic behavior of natural polyphenols by Xiao, Jianbo, Högger, Petra

“…The development of food fortified with polyphenols and polyphenol-rich foods represents a novel approach to prevent or attenuate type 2 diabetes. It has been…”
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Determination of Guanfacine in Oral Fluid and Serum of Children and Adolescents with Attention-Deficit/Hyperactivity Disorder: A Short Communication by Wohkittel, Christopher, Scherf-Clavel, Oliver, Fekete, Stefanie, Romanos, Marcel, Högger, Petra, Gerlach, Manfred

“…Guanfacine, a selective α2A-adrenoreceptor agonist, is a second-line medication for treating children and adolescents with attention-deficit/hyperkinetic…”
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Highly sensitive analysis of polyphenols and their metabolites in human blood cells using dispersive SPE extraction and LC-MS/MS by Mulek, Melanie, Hogger, Petra

“…Blood cells, particularly erythrocytes, present a significant compartment for distribution of drugs and endogenous compounds and have been suggested to be…”
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Fluorescence interference of polyphenols in assays screening for dipeptidyl peptidase IV inhibitory activity by Dirimanov, Stoyan, Högger, Petra

“…Polyphenols are plant‐derived natural compounds, which are attributed to various beneficial effects on human health. Therefore, they are extensively…”
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Plasma protein binding of polyphenols from maritime pine bark extract (USP) by Kurlbaum, Max, Högger, Petra

“…Maritime pine bark extract is monographed in the United States Pharmacopeia (USP) as a dietary supplement. As knowledge about active principles – protein…”
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Facilitated uptake of a bioactive metabolite of maritime pine bark extract (pycnogenol) into human erythrocytes by Kurlbaum, Max, Mülek, Melanie, Högger, Petra

“…Many plant secondary metabolites exhibit some degree of biological activity in humans. It is a common observation that individual plant-derived compounds in…”
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Antioxidant activity and inhibition of matrix metalloproteinases by metabolites of maritime pine bark extract (pycnogenol) by Grimm, Tanja, Schäfer, Angelika, Högger, Petra

“…The procyanidin-rich maritime pine bark extract Pycnogenol has well-documented antioxidant and anti-inflammatory activity. After oral administration of…”
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Effects of Pycnogenol on endothelial function in patients with stable coronary artery disease: a double-blind, randomized, placebo-controlled, cross-over study by ENSELEIT, Frank, SUDANO, Isabella, KRASNIQI, Nazmi, MATTER, Christian M, UHLENHUT, Klaus, HÖGGER, Petra, NEIDHART, Michel, LÜSCHER, Thomas F, RUSCHITZKA, Frank, NOLL, Georg, PERIAT, Daniel, WINNIK, Stephan, WOLFRUM, Mathias, FLAMMER, Andreas J, FRÖHLICH, Georg M, KAISER, Priska, HIRT, Astrid, HAILE, Sarah R

“…Extracts from pine tree bark containing a variety of flavonoids have been used in traditional medicine. Pycnogenol is a proprietary bark extract of the French…”
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Suppression of cytokine release by fluticasone furoate vs. mometasone furoate in human nasal tissue ex-vivo by Zhang, Nan, Van Crombruggen, Koen, Holtappels, Gabriele, Lan, Feng, Katotomichelakis, Michail, Zhang, Luo, Högger, Petra, Bachert, Claus

“…Topical glucocorticosteroids are the first line therapy for airway inflammation. Modern compounds with higher efficacy have been developed, but head-to-head…”
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Constituents and Metabolites of a French Oak Wood Extract (Robuvit ® ) in Serum and Blood Cell Samples of Women Undergoing Hysterectomy by Volpp, Linda, Ferianec, Vladimír, Ježovičová, Miriam, Ďuračková, Zdeňka, Scherf-Clavel, Oliver, Högger, Petra

“…Ellagitannins are signature constituents of oak wood and their consumption has been associated with various health benefits. , they undergo metabolic…”
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Stability of quercetin in DMEM and cell culture with A549 cells by Cao, Hui, Högger, Petra, Prieto, Miguel‐Angel, Simal‐Gandara, Jesus, Xiao, Jianbo

“…Quercetin is evidently unstable in Dulbecco's modified Eagle's medium (DMEM) at 37°C. However, the underlying mechanism of this instability is not clear yet…”
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Development of a novel model for comparative evaluation of intranasal pharmacokinetics and effects of anti-allergic nasal sprays by Baumann, Daniel, Bachert, Claus, Högger, Petra

“…Human respiratory tissue embedded into a solid matrix coated with artificial nasal fluid served as a new model for comparing tissue binding and…”
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Analgesic and antiinflammatory activity of Morinda citrifolia L. (Noni) fruit by Basar, Simla, Uhlenhut, Klaus, Högger, Petra, Schöne, Florian, Westendorf, Johannes

“…M. citrifolia is a tropical plant with a long tradition of medicinal use in Polynesia and tropical parts of eastern Asia and Australia. One of its favorite…”
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