Search Results - "Hétuin, D"

RIP3 is downregulated in human myeloid leukemia cells and modulates apoptosis and caspase-mediated p65/RelA cleavage by Nugues, A-L, El Bouazzati, H, Hétuin, D, Berthon, C, Loyens, A, Bertrand, E, Jouy, N, Idziorek, T, Quesnel, B

“…The receptor-interacting protein kinase 3 (RIP3) associates with RIP1 in a necrosome complex that can induce necroptosis, apoptosis, or cell proliferation. We…”
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GILZ inhibits the mTORC2 AKT pathway in BCR-ABL cells by Joha, S, Nugues, A-L, Hétuin, D, Berthon, C, Dezitter, X, Dauphin, V, Mahon, F-X, Roche-Lestienne, C, Preudhomme, C, Quesnel, B, Idziorek, T

“…The malignant phenotype of chronic myeloid leukemia (CML) is due to the abnormal tyrosine kinase activity of the BCR-ABL oncoprotein, which signals several…”
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BCR-ABL mutants spread resistance to non-mutated cells through a paracrine mechanism by Liu, J, Joha, S, Idziorek, T, Corm, S, Hetuin, D, Philippe, N, Preudhomme, C, Quesnel, B

“…Patients with chronic myeloid leukemia who become resistant to the Abl kinase inhibitor imatinib can be treated with dasatinib. This sequential treatment can…”
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Mis-splicing yields circular RNA molecules by Cocquerelle, C, Mascrez, B, Hétuin, D, Bailleul, B

“…We previously identified novel human ets-1 transcripts in which the normal order of exons is inverted, and demonstrated that although the order of exons is…”
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Gene transfer of CD154 and IL12 cDNA induces an anti-leukemic immunity in a murine model of acute leukemia by SAUDEMONT, A, BUFFENOIR, G, DENYS, A, DESREUMAUX, P, JOUY, N, HETUIN, D, BAUTERS, F, FENAUX, P, QUESNEL, B

“…IL12 is an essential cytokine for the generation of T helper 1 response, natural killer (NK) cells and cytotoxic T lymphocyte (CTL) stimulation. CD154 triggers…”
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γ-Irradiation enhances transgene expression in leukemic cells by VEREECQUE, R, SAUDEMONT, A, WICKHAM, T. T, GONZALEZ, R, HETUIN, D, FENAUX, P, QUESNEL, B

“…The majority of immunotherapy-based gene therapy protocols consist of ex vivo gene transfer in tumor cells. To prevent further in vivo growth, modified cells…”
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NK cells that are activated by CXCL10 can kill dormant tumor cells that resist CTL-mediated lysis and can express B7-H1 that stimulates T cells by Saudemont, Aurore, Jouy, Nathalie, Hetuin, Dominique, Quesnel, Bruno

“…Tumor dormancy is a phenomenon where small numbers of tumor cells persist in the host for months or years. We previously showed in the DA1-3b/C3H mouse model…”
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GILZ inhibits the mTORC2/AKT pathway in [BCR-ABL.sup.+] cells by Joha, S, Nugues, A.-L, Hetuin, D, Berthon, C, Dezitter, X, Dauphin, V, Mahon, F.-X, Roche-Lestienne, C, Preudhomme, C, Quesnel, B, Idziorek, T

“…The malignant phenotype of chronic myeloid leukemia (CML) is due to the abnormal tyrosine kinase activity of the BCR-ABL oncoprotein, which signals several…”
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GILZ inhibits the mTORC2/AKT pathway in BCR-ABL super(+) cells by Joha, S, Nugues, A-L, Hetuin, D, Berthon, C, Dezitter, X, Dauphin, V, Mahon, F-X, Roche-Lestienne, C, Preudhomme, C, Quesnel, B, Idziorek, T

“…The malignant phenotype of chronic myeloid leukemia (CML) is due to the abnormal tyrosine kinase activity of the BCR-ABL oncoprotein, which signals several…”
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Gene transfer of GM-CSF, CD80 and CD154 cDNA enhances survival in a murine model of acute leukemia with persistence of a minimal residual disease by Vereecque, R, Buffenoir, G, Preudhomme, C, Hetuin, D, Bauters, F, Fenaux, P, Quesnel, B

“…Gene transfer of various cytokines and co-stimulatory molecules has been reported to induce a potent antileukemic immunity in murine models, however, the…”
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Induction of leukemia-specific CD8 cytotoxic t cells with autologous myeloid leukemic cells maturated with a fiber-modified adenovirus encoding TNF-α by Saudemont, Aurore, Corm, Selim, Wickham, Thomas, Hetuin, Dominique, Quesnel, Bruno

“…Acute myeloid leukemia (AML) cells can be differentiated into dendritic cells (DCs) using appropriate combinations of cytokines but generation of autologous…”
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γ‐Ray irradiation induces B7.1 expression in myeloid leukaemic cells by Vereecque, Rodolphe, Buffenoir, Geraldine, Gonzalez, Ricardo, Cambier, Nathalie, Hetuin, Dominique, Bauters, Francis, Fenaux, Pierre, Quesnel, Bruno

“…Expression of B7 molecules provides co‐stimulatory signals to T lymphocytes, which prevent the induction of anergy. It has been previously reported that B7.1…”
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[gamma]-Irradiation enhances transgene expression in leukemic cells by Vereecque, R, Saudemont, A, Wickham, T J, Gonzalez, R, Hetuin, D, Fenaux, P, Quesnel, B

“…The majority of immunotherapy-based gene therapy protocols consist of ex vivo gene transfer in tumor cells. To prevent further in vivo growth, modified cells…”
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Transduction of bone marrow cells by the AdZ.F(pK7) modified adenovirus demonstrates preferential gene transfer in myeloma cells by Gonzalez, R, Vereecque, R, Wickham, T J, Facon, T, Hetuin, D, Kovesdi, I, Bauters, F, Fenaux, P, Quesnel, B

“…Adenoviral vectors can efficiently infect myeloma cell lines, but transduction of fresh myeloma cells performed at low multiplicity of infections (MOIs) showed…”
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Gene transfer of GM-CSF, CD80 and CD 154 cDNA enhances survival in a murine model of acute leukemia with persistence of a minimal residual disease by VEREECQUE, R, BUFFENOIR, G, PREUDHOMME, C, HETUIN, D, BAUTERS, F, FENAUX, P, QUESNEL, B

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Transfer of p16inka/CDKN2 gene in leukaemic cell lines inhibits cell proliferation by Quesnel, B, Preudhomme, C, Lepelley, P, Hetuin, D, Vanrumbeke, M, Bauters, F, Velu, T, Fenaux, P

“…The gene encoding for p16ink4a, a negative regulator of transition between G1 and S phase, is homozygously deleted in a large proportion of acute lymphoblastic…”
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