Search Results - "Hébert, Caroline"
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Optimal interlesion distance for 90 and 50 watt radiofrequency applications with low ablation index values: experimental findings in a chronic ovine model
Published in Europace (London, England) (02-11-2023)“…Abstract Aims The optimal interlesion distance (ILD) for 90 and 50 W radiofrequency applications with low ablation index (AI) values in the atria has not been…”
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Understanding Rare Disease Experiences Through the Concept of Morally Problematic Situations
Published in HEC forum (01-09-2024)“…Rare diseases, defined as having a prevalence inferior to 1/2000, are poorly understood scientifically and medically. Appropriate diagnoses and treatments are…”
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An Ethics Action Plan for Rare Disease Care: Participatory Action Research Approach
Published in Journal of participatory medicine (23-11-2023)“…Owing to their low prevalence, rare diseases are poorly addressed in the scientific literature and clinical practice guidelines. Thus, health care workers are…”
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FIZZ1, a novel cysteine-rich secreted protein associated with pulmonary inflammation, defines a new gene family
Published in The EMBO journal (01-08-2000)“…Bronchoalveolar lavage fluid from mice with experimentally induced allergic pulmonary inflammation contains a novel 9.4 kDa cysteine‐rich secreted protein,…”
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Distinct but Overlapping Epitopes for the Interaction of a CC-Chemokine with CCR1, CCR3, and CCR5
Published in Biochemistry (Easton) (12-08-1997)“…Chemokines play an important role in inflammation. The mechanism via which they bind to more than one receptor and activate them is not well understood. The…”
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Monomeric variants of IL‐8: Effects of side chain substitutions and solution conditions upon dimer formation
Published in Protein science (01-03-1997)“…IL‐8 dimers have been observed in NMR and X‐ray structures of the protein. We have engineered IL‐8 monomers by mutations of residues throughout the dimer…”
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Morally Problematic Situations Encountered by Adults Living With Rare Diseases
Published in AJOB empirical bioethics (02-07-2024)“…Rare diseases are generally poorly understood from scientific and medical standpoints due, to their complexity and low prevalence. As a result, individuals…”
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IL‐8 single‐chain homodimers and heterodimers: Interactions with the chemokine receptors CXCR1, CXCR2, and DARC
Published in Protein science (01-03-1997)“…Covalent single‐chain dimers of the chemokine interleukin‐8 (IL‐8) have been designed to mimic the dimeric form of IL‐8 in solution and facilitate the…”
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A NEUTRALIZING MONOCLONAL ANTIBODY SPECIFIC FOR THE DIMER INTERFACE REGION OF IL-8
Published in Cytokine (Philadelphia, Pa.) (01-11-2000)“…We have generated two mAbs, 6G4.2.5 and A5.12.14, that are similarly capable of neutralizing the biologic activity of wild-type IL-8. To characterize these…”
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Importance of Interleukin-8 in the Development of Reexpansion Lung Injury in Rabbits
Published in American journal of respiratory and critical care medicine (01-03-2000)“…Reexpansion of a collapsed lung induces increased microvascular permeability leading to reexpansion pulmonary edema (REPE). This study was designed to prove…”
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Identification of G-protein binding sites of the human interleukin-8 receptors by functional mapping of the intracellular loops
Published in The FASEB journal (01-10-1996)“…Interleukin 8 (IL-8) is considered to be a major mediator of the inflammatory response. Recent evidence indicates that a direct physical association occurs…”
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Inhibition Of Interleukin-8 Blocks Myocardial Ischemia-Reperfusion Injury
Published in The Journal of thoracic and cardiovascular surgery (01-07-1998)“…Introduction: Interleukin-8 is thought to play a role in neutrophil activation and transcapillary migration into the interstitium. Because neutrophils are…”
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Effects of chronic antidepressant treatments on 5-HT and NA transporters in rat brain: an autoradiographic study
Published in Neurochemistry international (2001)“…Tricyclic antidepressants and serotonin (5-HT) uptake inhibitors rapidly block uptake sites, or transporters; however, their therapeutic effects are only seen…”
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Acid aspiration-induced lung injury in rabbits is mediated by interleukin-8-dependent mechanisms
Published in The Journal of clinical investigation (01-07-1995)“…Acid aspiration lung injury may be mediated primarily by neutrophils recruited to the lung by acid-induced cytokines. We hypothesized that a major acid-induced…”
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15
Left ventricular summit premature ventricular contractions treated by venous ethanol infusion: Scar assessment by magnetic resonance imaging
Published in Pacing and clinical electrophysiology (01-10-2023)“…Left ventricular (LV) summit premature ventricular contractions (PVCs) are often unresponsive to radiofrequency (RF) ablation. Retrograde venous ethanol…”
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Monoclonal antibodies detect different distribution patterns of IL-8 receptor A and IL-8 receptor B on human peripheral blood leukocytes
Published in The Journal of immunology (1950) (15-12-1994)“…mAbs previously reported to be specific for IL-8R type A (IL-8R-A) and mAbs specific for IL-8R type B (IL-8R-B), which are described in this paper, were used…”
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Red blood cells are a sink for interleukin 8, a leukocyte chemotaxin
Published in The Journal of clinical investigation (01-10-1991)“…IL-8 (also known as neutrophil-activating peptide 1) is recognized as a potent effector of neutrophil functions. Several different cell types that contact…”
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Scanning mutagenesis of interleukin-8 identifies a cluster of residues required for receptor binding
Published in The Journal of biological chemistry (05-10-1991)“…In order to identify residues required for the binding of interleukin-8 (IL-8) to its receptor, mutants were constructed in which clusters of charged amino…”
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Distribution of serotonin, its metabolites and 5-HT transporters in the neostriatum of Lurcher and weaver mutant mice
Published in Neurochemistry international (01-09-2001)“…Serotonin (5-HT) uptake sites, or transporters, were measured in the neostriatum (caudate putamen) of wild type (+/+) mice and heterozygous (wv/+) and…”
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Chemoattractant cross-desensitization of the human neutrophil IL-8 receptor involves receptor internalization and differential receptor subtype regulation
Published in The Journal of immunology (1950) (01-02-1997)“…Human neutrophils undergo rapid homologous receptor desensitization following repeated stimulation with chemoattractants such as IL-8, C5a, and FMLP. It has…”
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