Search Results - "Hæffner, Fredrik"

Diastereo- and Enantioselective Reactions of Bis(pinacolato)diboron, 1,3-Enynes, and Aldehydes Catalyzed by an Easily Accessible Bisphosphine–Cu Complex by Meng, Fanke, Haeffner, Fredrik, Hoveyda, Amir H

“…Catalytic enantio­selective multicomponent processes involving bis­(pinacolato)­diboron [B2(pin)2], 1,3-enynes, and aldehydes are disclosed; the resulting…”
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Barrier to Enantiomerization of Unstabilized, Chelated, and Dipole-Stabilized 2-Lithiopyrrolidines by Ashweek, Neil J, Brandt, Peter, Coldham, Iain, Dufour, Samuel, Gawley, Robert E, Klein, Rosalyn, Sanchez-Jimenez, Graciela

“…Kinetics experiments have been used to establish the free energy, enthalpy, and entropy of activation for the enantiomerization of three structural classes of…”
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Degradable Vinyl Random Copolymers via Photocontrolled Radical Ring‐Opening Cascade Copolymerization by Wang, Wenqi, Zhou, Zefeng, Sathe, Devavrat, Tang, Xuanting, Moran, Stephanie, Jin, Jing, Haeffner, Fredrik, Wang, Junpeng, Niu, Jia

“…Degradable vinyl polymers by radical ring‐opening polymerization are promising solutions to the challenges caused by non‐degradable vinyl plastics. However,…”
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Carbohydrate-Catalyzed Enantioselective Alkene Diboration: Enhanced Reactivity of 1,2-Bonded Diboron Complexes by Fang, Lichao, Yan, Lu, Haeffner, Fredrik, Morken, James P

“…Catalytic enantioselective diboration of alkenes is accomplished with readily available carbohydrate-derived catalysts. Mechanistic experiments suggest the…”
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A Boron Alkylidene–Alkene Cycloaddition Reaction: Application to the Synthesis of Aphanamal by Liu, Xun, Deaton, T. Maxwell, Haeffner, Fredrik, Morken, James P.

“…We describe an unusual net [2+2] cycloaddition reaction between boron alkylidenes and unactivated alkenes. This reaction provides a new method for the…”
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Catalytic enantioselective addition of organoboron reagents to fluoroketones controlled by electrostatic interactions by Lee, KyungA, Silverio, Daniel L., Torker, Sebastian, Robbins, Daniel W., Haeffner, Fredrik, van der Mei, Farid W., Hoveyda, Amir H.

“…Organofluorine compounds are central to modern chemistry, and broadly applicable transformations that generate them efficiently and enantioselectively are in…”
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NHC–Cu-Catalyzed Protoboration of Monosubstituted Allenes. Ligand-Controlled Site Selectivity, Application to Synthesis and Mechanism by Meng, Fanke, Jung, Byunghyuck, Haeffner, Fredrik, Hoveyda, Amir H

“…Two types of NHC–Cu complexes catalyze protoborations of terminal allenes to afford valuable 1,1- or trisubstituted vinylboron species with high site…”
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Simple organic molecules as catalysts for enantioselective synthesis of amines and alcohols by Silverio, Daniel L., Torker, Sebastian, Pilyugina, Tatiana, Vieira, Erika M., Snapper, Marc L., Haeffner, Fredrik, Hoveyda, Amir H.

“…A set of small organic molecules catalyse reactions of unsaturated organoboron reagents with imines and carbonyls to produce amines and alcohols in high…”
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Scope and Mechanism of the Pt-Catalyzed Enantioselective Diboration of Monosubstituted Alkenes by Coombs, John R, Haeffner, Fredrik, Kliman, Laura T, Morken, James P

“…The Pt-catalyzed enantioselective diboration of terminal alkenes can be accomplished in an enantioselective fashion in the presence of chiral phosphonite…”
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An Efficient, Practical, and Enantioselective Method for Synthesis of Homoallenylamides Catalyzed by an Aminoalcohol-Derived, Boron-Based Catalyst by Wu, Hao, Haeffner, Fredrik, Hoveyda, Amir H

“…A practical catalytic method for enantio­selective addition of an allene unit to aldimines is disclosed. Transformations are promoted by an in-situ-generated…”
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Carbohydrate/DBU Cocatalyzed Alkene Diboration: Mechanistic Insight Provides Enhanced Catalytic Efficiency and Substrate Scope by Yan, Lu, Meng, Yan, Haeffner, Fredrik, Leon, Robert M, Crockett, Michael P, Morken, James P

“…A mechanistic investigation of the carbohydrate/DBU cocatalyzed enantioselective diboration of alkenes is presented. These studies provide an understanding of…”
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NHC–Cu-Catalyzed Silyl Conjugate Additions to Acyclic and Cyclic Dienones and Dienoates. Efficient Site-, Diastereo- and Enantioselective Synthesis of Carbonyl-Containing Allylsilanes by Lee, Kang-sang, Wu, Hao, Haeffner, Fredrik, Hoveyda, Amir H

“…Efficient and highly diastereo- and enantioselective conjugate additions of phenyldimethylsilyl units to acyclic and cyclic dienones and dienoates are…”
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1,2-Azaborine’s Distinct Electronic Structure Unlocks Two New Regioisomeric Building Blocks via Resolution Chemistry by McConnell, Cameron R, Haeffner, Fredrik, Baggett, Andrew W, Liu, Shih-Yuan

“…Two new 1,2-azaborine building blocks that enable the broad diversification of previously not readily accessible C4 and C5 ring positions of the 1,2-azaborine…”
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Monobenzofused 1,4-Azaborines: Synthesis, Characterization, and Discovery of a Unique Coordination Mode by Xu, Senmiao, Haeffner, Fredrik, Li, Bo, Zakharov, Lev N., Liu, Shih-Yuan

“…We report the first general synthesis of boron‐substituted monobenzofused 1,4‐azaborines using ring‐closing metathesis of an enamine‐containing diene as a key…”
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Electronically Activated Organoboron Catalysts for Enantioselective Propargyl Addition to Trifluoromethyl Ketones by Mszar, Nicholas W., Mikus, Malte S., Torker, Sebastian, Haeffner, Fredrik, Hoveyda, Amir H.

“…A broadly applicable, practical, scalable, efficient and highly α‐ and enantioselective method for addition of a silyl‐protected propargyl moiety to…”
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Enantioselective silyl protection of alcohols promoted by a combination of chiral and achiral Lewis basic catalysts by Manville, Nathan, Alite, Hekla, Haeffner, Fredrik, Hoveyda, Amir H., Snapper, Marc L.

“…Catalytic enantioselective monosilylations of diols and polyols furnish valuable alcohol-containing molecules in high enantiomeric purity. These…”
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A Robust, Efficient, and Highly Enantioselective Method for Synthesis of Homopropargyl Amines by Vieira, Erika M., Haeffner, Fredrik, Snapper, Marc L., Hoveyda, Amir H.

“…Fast, robust, selective: Copper‐catalyzed enantioselective additions of homopropargyl groups to a wide range of aldimines proceed readily and with high…”
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Mechanism for Catechol Ring-Cleavage by Non-Heme Iron Extradiol Dioxygenases by Siegbahn, Per E. M, Haeffner, Fredrik

“…The catalytic mechanism of the non-heme iron extradiol dioxygenases has been studied using hybrid density functional theory. These enzymes cleave a C−C bond…”
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Degradable Vinyl Random Copolymers via Photocontrolled Radical Ring‐Opening Cascade Copolymerization by Wang, Wenqi, Zhou, Zefeng, Sathe, Devavrat, Tang, Xuanting, Moran, Stephanie, Jin, Jing, Haeffner, Fredrik, Wang, Junpeng, Niu, Jia

“…Degradable vinyl polymers by radical ring‐opening polymerization are promising solutions to the challenges caused by non‐degradable vinyl plastics. However,…”
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A structural basis for enantioselective inhibition of Candida rugosa lipase by long‐chain aliphatic alcohols by Holmquist, Mats, Hæffner, Fredrik, Norin, Torbjörn, Hult, Karl

“…Molecular modeling showed that the enantiomers of heptyl 2‐methyldecanoate are productively bound to the active site of Candida rugosa lipase in quite…”
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