Search Results - "Håkansson, Helen"

Cumulative health risk assessment of 17 perfluoroalkylated and polyfluoroalkylated substances (PFASs) in the Swedish population by Borg, Daniel, Lund, Bert-Ove, Lindquist, Nils-Gunnar, Håkansson, Helen

“…Humans are simultaneously exposed to a multitude of chemicals. Human health risk assessment of chemicals is, however, normally performed on single substances,…”
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Effects of polybrominated diphenyl ethers (PBDEs) and polychlorinated biphenyls (PCBs) on thyroid hormone and vitamin A levels in rats and mice by HALLGREN, Sara, SINJARI, Taha, HAKANSSON, Helen, DARNERUD, Per Ola

“…The ability of the commercial polybrominated diphenyl ether (PBDE) preparation Bromkal 70-5 DE to alter thyroid hormone and vitamin A levels as well as…”
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Identification of the Tryptophan Photoproduct 6-Formylindolo[3,2-b]carbazole, in Cell Culture Medium, as a Factor That Controls the Background Aryl Hydrocarbon Receptor Activity by Öberg, Mattias, Bergander, Linda, Håkansson, Helen, Rannug, Ulf, Rannug, Agneta

“…The presence of high affinity ligands for the aryl hydrocarbon receptor (AhR) in cell culture medium has generally been overlooked. Such compounds may confound…”
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Role of retinoids in biology and toxicology by Hakansson, H

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Effect of 2,3,7,8-Tetrachlorodibenzo-p-dioxin on the Expression of Cytochrome P450 1A1, the Aryl Hydrocarbon Receptor, and the Aryl Hydrocarbon Receptor Nuclear Translocator in Rat Brain and Pituitary by Huang, Ping, Rannug, Agneta, Ahlbom, Eva, Håkansson, Helen, Ceccatelli, Sandra

“…2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) and related substances are ubiquitous environmental pollutants causing a wide variety of pathological alterations,…”
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Craniofacial form is altered by chronic adult exposure to 2,3,7,8-tetrachlorodibenzo- p -dioxin (TCDD) in Han/Wistar and Long-Evans rats with different aryl hydrocarbon receptor (AhR) structures by Sholts, Sabrina B, Esteban, Javier, Herlin, Maria, Viluksela, Matti, Håkansson, Helen

“…Mammalian bone has shown a variety of responses to 2,3,7,8-tetrachlorodibenzo- -dioxin (TCDD) exposure in experimental and wildlife studies. Although many…”
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Regulatory needs and activities to address the retinoid system in the context of endocrine disruption: The European viewpoint by Grignard, Elise, Håkansson, Helen, Munn, Sharon

“…•Endocrine disruption is a complex and important toxicological problem to consider.•The retinoid system is evolutionary conserved and central for endocrine…”
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The 2005 World Health Organization Reevaluation of Human and Mammalian Toxic Equivalency Factors for Dioxins and Dioxin-Like Compounds by Van den Berg, Martin, Birnbaum, Linda S., Denison, Michael, De Vito, Mike, Farland, William, Feeley, Mark, Fiedler, Heidelore, Hakansson, Helen, Hanberg, Annika, Haws, Laurie, Rose, Martin, Safe, Stephen, Schrenk, Dieter, Tohyama, Chiharu, Tritscher, Angelika, Tuomisto, Jouko, Tysklind, Mats, Walker, Nigel, Peterson, Richard E.

“…In June 2005, a World Health Organization (WHO)-International Programme on Chemical Safety expert meeting was held in Geneva during which the toxic equivalency…”
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Risk for animal and human health related to the presence of dioxins and dioxin‐like PCBs in feed and food by Knutsen, Helle Katrine, Alexander, Jan, Barregård, Lars, Bignami, Margherita, Brüschweiler, Beat, Ceccatelli, Sandra, Cottrill, Bruce, Dinovi, Michael, Edler, Lutz, Grasl‐Kraupp, Bettina, Hogstrand, Christer, Nebbia, Carlo Stefano, Oswald, Isabelle P, Petersen, Annette, Rose, Martin, Roudot, Alain‐Claude, Schwerdtle, Tanja, Vleminckx, Christiane, Vollmer, Günter, Wallace, Heather, Fürst, Peter, Håkansson, Helen, Halldorsson, Thorhallur, Lundebye, Anne‐Katrine, Pohjanvirta, Raimo, Rylander, Lars, Smith, Andrew, van Loveren, Henk, Waalkens‐Berendsen, Ine, Zeilmaker, Marco, Binaglia, Marco, Gómez Ruiz, José Ángel, Horváth, Zsuzsanna, Christoph, Eugen, Ciccolallo, Laura, Ramos Bordajandi, Luisa, Steinkellner, Hans, Hoogenboom, Laurentius (Ron)

“…The European Commission asked EFSA for a scientific opinion on the risks for animal and human health related to the presence of dioxins (PCDD/Fs) and DL‐PCBs…”
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Scientific principles for the identification of endocrine-disrupting chemicals: a consensus statement by Solecki, Roland, Kortenkamp, Andreas, Bergman, Åke, Chahoud, Ibrahim, Degen, Gisela H., Dietrich, Daniel, Greim, Helmut, Håkansson, Helen, Hass, Ulla, Husoy, Trine, Jacobs, Miriam, Jobling, Susan, Mantovani, Alberto, Marx-Stoelting, Philip, Piersma, Aldert, Ritz, Vera, Slama, Remy, Stahlmann, Ralf, van den Berg, Martin, Zoeller, R. Thomas, Boobis, Alan R.

“…Endocrine disruption is a specific form of toxicity, where natural and/or anthropogenic chemicals, known as “endocrine disruptors” (EDs), trigger adverse…”
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Risk to all or none? A comparative analysis of controversies in the health risk assessment of Bisphenol A by BERONIUS, Anna, RUDEN, Christina, HAKANSSON, Helen, HANBERG, Annika

“…Bisphenol A (BPA) is an endocrine disruptor for which health risk assessment has proven controversial. Conclusions regarding health risks of BPA vary between…”
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Gender- and dose-related metabolome alterations in rat offspring after in utero and lactational exposure to PCB 180 by Pikkarainen, Antti, Lehtonen, Marko, Håkansson, Helen, Auriola, Seppo, Viluksela, Matti

“…Polychlorinated biphenyls (PCBs) are persistent environmental pollutants that are still causing potentially harmful effects to humans and wildlife. While the…”
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Phthalate Diesters and Their Metabolites in Human Breast Milk, Blood or Serum, and Urine as Biomarkers of Exposure in Vulnerable Populations by Högberg, Johan, Hanberg, Annika, Berglund, Marika, Skerfving, Staffan, Remberger, Mikael, Calafat, Antonia M., Filipsson, Agneta Falk, Jansson, Bo, Johansson, Niklas, Appelgren, Malin, Håkansson, Helen

“…Background: Phthalates may pose a risk for perinatal developmental effects. An important question relates to the choice of suitable biological matrices for…”
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Skeletal and dental effects on rats following in utero/lactational exposure to the non-dioxin-like polychlorinated biphenyl PCB 180 by Romero, Ashly N, Herlin, Maria, Finnilä, Mikko, Korkalainen, Merja, Håkansson, Helen, Viluksela, Matti, Sholts, Sabrina B

“…Polychlorinated biphenyls (PCBs) are a large class of persistent organic pollutants that are potentially harmful to human and wildlife health. Although a small…”
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Altered Retinoid Metabolism in Female Long-Evans and Han/Wistar Rats following Long-Term 2,3,7,8-Tetrachlorodibenzo-p-Dioxin (TCDD)-Treatment by Fletcher, Nick, Giese, Norbert, Schmidt, Carsten, Stern, Natalia, Lind, P. Monica, Viluksela, Matti, Tuomisto, Jouni T., Tuomisto, Jouko, Nau, Heinz, Håkansson, Helen

“…This study investigated the effects of long-term low-dose 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) exposure on retinoid, thyroid hormone, and vitamin D…”
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Role of aryl hydrocarbon receptor (AHR) in overall retinoid metabolism: Response comparisons to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) exposure between wild-type and AHR knockout mice by Esteban, Javier, Sánchez-Pérez, Ismael, Hamscher, Gerd, Miettinen, Hanna M., Korkalainen, Merja, Viluksela, Matti, Pohjanvirta, Raimo, Håkansson, Helen

“…•Circulating REOH and ATRA-concentrations were lower in AHRKO than WT mice.•TCDD had no effect on retinoid concentrations in AHRKO mice.•TCDD reduced liver…”
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Bone toxicity induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and the retinoid system: A causality analysis anchored in osteoblast gene expression and mouse data by Herlin, Maria, Sánchez-Pérez, Ismael, Esteban, Javier, Korkalainen, Merja, Barber, Xavier, Finnilä, Mikko A.J., Hamscher, Gerd, Joseph, Bertrand, Viluksela, Matti, Håkansson, Helen

“…•TCDD-induced effects on mouse bone are associated with increased circulating REOH.•TCDD represses Crabp2 expression indicating reduced nuclear translocation…”
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Effects of a high-fat diet and global aryl hydrocarbon receptor deficiency on energy balance and liver retinoid status in male Sprague-Dawley rats by Pohjanvirta, Raimo, Karppinen, Ira, Galbán-Velázquez, Suylen, Esteban, Javier, Håkansson, Helen, Sankari, Satu, Lindén, Jere

“…The physiological functions of the aryl hydrocarbon receptor (AHR) are only beginning to unfold. Studies in wildtype and AHR knockout (AHRKO) mice have…”
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Toxicological characterisation of two novel selective aryl hydrocarbon receptor modulators in Sprague-Dawley rats by Mahiout, Selma, Lindén, Jere, Esteban, Javier, Sánchez-Pérez, Ismael, Sankari, Satu, Pettersson, Lars, Håkansson, Helen, Pohjanvirta, Raimo

“…The aryl hydrocarbon receptor (AHR) mediates the toxicity of dioxins, but also plays important physiological roles. Selective AHR modulators, which elicit some…”
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Individual breast milk consumption and exposure to PCBs and PCDD/Fs in Hungarian infants: A time-course analysis of the first three months of lactation by Vigh, Éva, Colombo, Andrea, Benfenati, Emilio, Håkansson, Helen, Berglund, Marika, Bódis, József, Garai, János

“…Polychlorinated biphenyls (PCBs), polychlorinated dibenzo-p-dioxins (PCDDs) and polychlorinated dibenzofurans (PCDFs) are persistent, bioaccumulative and toxic…”
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