Search Results - "Håkansson, Anders P"

HAMLET a human milk protein‐lipid complex induces a pro‐inflammatory phenotype of myeloid cells by Vansarla, Goutham, Håkansson, Anders P, Bergenfelz, Caroline

“…HAMLET is a protein‐lipid complex with a specific and broad bactericidal and tumoricidal activity, that lacks cytotoxic activity against healthy cells. In this…”
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Biofilm-dispersed pneumococci induce elevated leukocyte and platelet activation by Chao, Yashuan, Mørch, Martina, Håkansson, Anders P, Shannon, Oonagh

“…(the pneumococcus) effectively colonizes the human nasopharynx, but can migrate to other host sites, causing infections such as pneumonia and sepsis. Previous…”
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Internalization and Trafficking of Nontypeable Haemophilus influenzae in Human Respiratory Epithelial Cells and Roles of IgA1 Proteases for Optimal Invasion and Persistence by Clementi, Cara F, Håkansson, Anders P, Murphy, Timothy F

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Treatment of Mouse Infants with Amoxicillin, but Not the Human Milk-Derived Antimicrobial HAMLET, Impairs Lung Th17 Responses by Shekhar, Sudhanshu, Brar, Navdeep Kaur, Håkansson, Anders P, Petersen, Fernanda Cristina

“…Emerging evidence suggests differential effects of therapeutic antibiotics on infant T cell responses to pathogens. In this study, we explored the impact of…”
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Capsule Independent Antimicrobial Activity Induced by Nanochitosan against Streptococcus pneumoniae by Alqahtani, Fulwah Y., Aleanizy, Fadilah S., El Tahir, Eram, Alowais, Hessa, Binkelaib, Assalh, Alwathlan, Bdour, Al-Bdrawy, Asmaa, Håkansson, Anders P., Alsarra, Ibrahim

“…Background: Streptococcus pneumoniae remains a major cause of community-acquired pneumonia, meningitis, and other diseases, contributing significantly to high…”
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BAMLET kills chemotherapy-resistant mesothelioma cells, holding oleic acid in an activated cytotoxic state by Rath, Emma M, Cheng, Yuen Yee, Pinese, Mark, Sarun, Kadir H, Hudson, Amanda L, Weir, Christopher, Wang, Yiwei D, Håkansson, Anders P, Howell, Viive M, Liu, Guo Jun, Reid, Glen, Knott, Robert B, Duff, Anthony P, Church, W Bret

“…Malignant pleural mesothelioma is an aggressive cancer with poor prognosis. Here we have investigated in vitro efficacy of BAMLET and BLAGLET complexes…”
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Oleic acid is a key cytotoxic component of HAMLET-like complexes by Permyakov, Sergei E, Knyazeva, Ekaterina L, Khasanova, Leysan M, Fadeev, Roman S, Zhadan, Andrei P, Roche-Hakansson, Hazeline, Håkansson, Anders P, Akatov, Vladimir S, Permyakov, Eugene A

“…HAMLET is a complex of α-lactalbumin (α-LA) with oleic acid (OA) that selectively kills tumor cells and Streptococcus pneumoniae. To assess the contribution of…”
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Monitoring changes in membrane polarity, membrane integrity, and intracellular ion concentrations in Streptococcus pneumoniae using fluorescent dyes by Clementi, Emily A, Marks, Laura R, Roche-Håkansson, Hazeline, Håkansson, Anders P

“…Membrane depolarization and ion fluxes are events that have been studied extensively in biological systems due to their ability to profoundly impact cellular…”
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Small-angle X-ray scattering of BAMLET at pH 12: A complex of α-lactalbumin and oleic acid by Rath, Emma M., Duff, Anthony P., Håkansson, Anders P., Knott, Robert B., Church, W. Bret

“…ABSTRACT BAMLET (Bovine Alpha‐lactalbumin Made LEthal to Tumors) is a member of the family of the HAMLET‐like complexes, a novel class of protein‐based…”
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Structure and Potential Cellular Targets of HAMLET-like Anti-Cancer Compounds made from Milk Components by Rath, Emma M, Duff, Anthony P, Håkansson, Anders P, Vacher, Catherine S, Liu, Guo Jun, Knott, Robert B, Church, William Bret

“…The HAMLET family of compounds (Human Alpha-lactalbumin Made Lethal to Tumours) was discovered during studies on the properties of human milk, and is a class…”
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A novel method for preparation of HAMLET-like protein complexes by Permyakov, Sergei E., Knyazeva, Ekaterina L., Leonteva, Marina V., Fadeev, Roman S., Chekanov, Aleksei V., Zhadan, Andrei P., Håkansson, Anders P., Akatov, Vladimir S., Permyakov, Eugene A.

“…Some natural proteins induce tumor-selective apoptosis. α-Lactalbumin (α-LA), a milk calcium-binding protein, is converted into an antitumor form, called…”
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Streptolysin O inhibits clathrin-dependent internalization of group A Streptococcus by Logsdon, Lauren K, Håkansson, Anders P, Cortés, Guadalupe, Wessels, Michael R

“…Group A Streptococcus (GAS) can be internalized by epithelial cells, including keratinocytes from human skin or pharyngeal epithelium. Internalization of GAS…”
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Enzymatic Characterization of Dihydrolipoamide Dehydrogenase from Streptococcus pneumoniae Harboring Its Own Substrate by Håkansson, Anders P., Smith, Alexander W.

“…This study describes the enzymatic characterization of dihydrolipoamide dehydrogenase (DLDH) from Streptococcus pneumoniae and is the first characterization of…”
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Klebsiella pneumoniae Biofilms and Their Role in Disease Pathogenesis by Guerra, Maria Eduarda Souza, Destro, Giulia, Vieira, Brenda, Lima, Alice S, Ferraz, Lucio Fabio Caldas, Hakansson, Anders P, Darrieux, Michelle, Converso, Thiago Rojas

“…The ability to form biofilms is a crucial virulence trait for several microorganisms, including - a Gram-negative encapsulated bacterium often associated with…”
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A particulate matter: How environmental irritants and particulate matter increase sensitivity to bacterial respiratory tract infections. Commentary for “Underground railway particulate matter and susceptibility to pneumococcal infection” by Hakansson, Anders P.

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Interkingdom signaling induces Streptococcus pneumoniae biofilm dispersion and transition from asymptomatic colonization to disease by Marks, Laura R, Davidson, Bruce A, Knight, Paul R, Hakansson, Anders P

“…Streptococcus pneumoniae is a common human nasopharyngeal commensal colonizing 10% to 40% of healthy individuals, depending on age. Despite a low invasive…”
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In Vitro and In Vivo Biofilm Formation by Pathogenic Streptococci by Chao, Yashuan, Bergenfelz, Caroline, Håkansson, Anders P

“…This manuscript presents novel approaches to grow and evaluate Streptococcal biofilm formation using the human respiratory pathogen Streptococcus pneumoniae…”
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Streptococcus pyogenes Biofilm Growth In Vitro and In Vivo and Its Role in Colonization, Virulence, and Genetic Exchange by Marks, Laura R., Mashburn-Warren, Lauren, Federle, Michael J., Hakansson, Anders P.

“…Background. Group A streptococcus (GAS) commonly colonizes the oropharynx and nonintact skin. However, colonization has been little studied and the role of…”
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Pneumococcal Interactions with Epithelial Cells Are Crucial for Optimal Biofilm Formation and Colonization In Vitro and In Vivo by MARKS, Laura R, LYER PARAMESWARAN, G, HAKANSSON, Anders P

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Biofilm Formation Enhances Fomite Survival of Streptococcus pneumoniae and Streptococcus pyogenes by Marks, Laura R, Reddinger, Ryan M, Hakansson, Anders P

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