Search Results - "Häkkinen, Suvi T."

Single Cell Protein-State-of-the-Art, Industrial Landscape and Patents 2001-2016 by Ritala, Anneli, Häkkinen, Suvi T, Toivari, Mervi, Wiebe, Marilyn G

“…By 2050, the world would need to produce 1,250 million tonnes of meat and dairy per year to meet global demand for animal-derived protein at current…”
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Hairy Root Cultures-A Versatile Tool With Multiple Applications by Gutierrez-Valdes, Noemi, Häkkinen, Suvi T, Lemasson, Camille, Guillet, Marina, Oksman-Caldentey, Kirsi-Marja, Ritala, Anneli, Cardon, Florian

“…Hairy roots derived from the infection of a plant by ) bacteria, can be obtained from a wide variety of plants and allow the production of highly diverse…”
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Life cycle assessment of plant cell cultures by Kobayashi, Yumi, Kärkkäinen, Elviira, Häkkinen, Suvi T., Nohynek, Liisa, Ritala, Anneli, Rischer, Heiko, Tuomisto, Hanna L.

“…A novel food such as plant cell culture (PCC) is an important complementary asset for traditional agriculture to tackle global food insecurity. To evaluate…”
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Jasmonate signaling involves the abscisic acid receptor PYL4 to regulate metabolic reprogramming in Arabidopsis and tobacco by Lackman, Petri, González-Guzmán, Miguel, Tilleman, Sofie, Carqueijeiro, Inês, Pérez, Amparo Cuéllar, Moses, Tessa, Seo, Mitsunori, Kanno, Yuri, Häkkinen, Suvi T, Van Montagu, Marc C.E, Thevelein, Johan M, Maaheimo, Hannu, Oksman-Caldentey, Kirsi-Marja, Rodriguez, Pedro L, Rischer, Heiko, Goossens, Alain

“…The phytohormones jasmonates (JAs) constitute an important class of elicitors for many plant secondary metabolic pathways. However, JAs do not act…”
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Tailoring sensory properties of plant cell cultures for food use by Ritala, Anneli, Heiniö, Raija-Liisa, Häkkinen, Suvi T., Lille, Martina, Hyytiäinen-Pabst, Tiina, Rischer, Heiko

“…[Display omitted] •Rowan (R) and Arctic bramble (Ab) plant cell cultures (PCC) have potential in food use.•Dry matter of R & Ab PCCs contain ∼ 18–22% of…”
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Inactivation of the germacrene A synthase genes by CRISPR/Cas9 eliminates the biosynthesis of sesquiterpene lactones in Cichorium intybus L by Cankar, Katarina, Bundock, Paul, Sevenier, Robert, Häkkinen, Suvi T., Hakkert, Johanna Christina, Beekwilder, Jules, Meer, Ingrid M., Both, Michiel, Bosch, Dirk

“…Chicory (Cichorium intybus var. sativum) is an industrial crop species cultivated for the production of a fructose polymer inulin, which is used as a…”
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Tobacco BY-2 Media Component Optimization for a Cost-Efficient Recombinant Protein Production by Häkkinen, Suvi T, Reuter, Lauri, Nuorti, Ninni, Joensuu, Jussi J, Rischer, Heiko, Ritala, Anneli

“…Plant cells constitute an attractive platform for production of recombinant proteins as more and more animal-free products and processes are desired. One of…”
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Plant cell cultures as food—aspects of sustainability and safety by Häkkinen, Suvi T., Nygren, Heli, Nohynek, Liisa, Puupponen-Pimiä, Riitta, Heiniö, Raija-Liisa, Maiorova, Natalia, Rischer, Heiko, Ritala, Anneli

“…Key message Sustainability and safety aspects of plant cell cultures as food are presented. Applicability of dairy side streams as carbon source and use of…”
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Improving yield of a recombinant biologic in a Brassica hairy root manufacturing process by Gutierrez‐Valdes, Noemi, Häkkinen, Suvi T., Lemasson, Camille, Groot, Jonas, Ele‐Ekouna, Jean‐Pierre, Guillet, Marina, Cardon, Florian, Ritala, Anneli

“…Hairy root systems have proven to be a viable alternative for recombinant protein production. For recalcitrant proteins, maximizing the productivity of hairy…”
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Chicory Extracts and Sesquiterpene Lactones Show Potent Activity against Bacterial and Fungal Pathogens by Häkkinen, Suvi T., Soković, Marina, Nohynek, Liisa, Ćirić, Ana, Ivanov, Marija, Stojković, Dejan, Tsitko, Irina, Matos, Melanie, Baixinho, João P., Ivasiv, Viktoriya, Fernández, Naiara, Nunes dos Santos, Claudia, Oksman-Caldentey, Kirsi-Marja

“…Chicory (Cichorium intybus L.) is an important industrial crop cultivated mainly to extract the dietary fiber inulin. However, chicory also contains bioactive…”
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Exploring the Metabolic Stability of Engineered Hairy Roots after 16 Years Maintenance by Häkkinen, Suvi T, Moyano, Elisabeth, Cusidó, Rosa M, Oksman-Caldentey, Kirsi-Marja

“…Plants remain a major source of new drugs, leads and fine chemicals. Cell cultures deriving from plants offer a fascinating tool to study plant metabolic…”
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Production of tropane alkaloids in diploid and tetraploid plants and in vitro hairy root cultures of Egyptian henbane (Hyoscyamus muticus L.) by Dehghan, Esmail, Häkkinen, Suvi T., Oksman-Caldentey, Kirsi-Marja, Shahriari Ahmadi, Farajollah

“…In this study, the effects of ploidy level and culture medium were studied on the production of tropane alkaloids. We have successfully produced stable…”
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Molecular farming in tobacco hairy roots by triggering the secretion of a pharmaceutical antibody by Häkkinen, Suvi T., Raven, Nicole, Henquet, Maurice, Laukkanen, Marja-Leena, Anderlei, Tibor, Pitkänen, Juha-Pekka, Twyman, Richard M., Bosch, Dirk, Oksman-Caldentey, Kirsi-Marja, Schillberg, Stefan, Ritala, Anneli

“…ABSTRACT Recombinant pharmaceutical proteins expressed in hairy root cultures can be secreted into the medium to improve product homogeneity and to facilitate…”
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Biotransformation of Cyclodextrine-Complexed Semisynthetic Betulin Derivatives by Plant Cells by Häkkinen, Suvi T, Nygren, Heli, Maiorova, Natalia, Haavikko, Raisa, Alakurtti, Sami, Yli-Kauhaluoma, Jari, Rischer, Heiko, Oksman-Caldentey, Kirsi-Marja

“…In this study, three semisynthetic betulonic acid-based compounds, 20(29)-dihydrolup-2-en[2,3- ]isoxazol-28-oic acid, 1-betulonoylpyrrolidine, and…”
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Bioconversion to Raspberry Ketone is Achieved by Several Non-related Plant Cell Cultures by Häkkinen, Suvi T, Seppänen-Laakso, Tuulikki, Oksman-Caldentey, Kirsi-Marja, Rischer, Heiko

“…Bioconversion, i.e., the use of biological systems to perform chemical changes in synthetic or natural compounds in mild conditions, is an attractive tool for…”
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Comparison of plant-based expression platforms for the heterologous production of geraniol by Vasilev, Nikolay, Schmitz, Christian, Dong, Lemeng, Ritala, Anneli, Imseng, Nicole, Häkkinen, Suvi T, van der Krol, Sander, Eibl, Regine, Oksman-Caldentey, Kirsi-Marja, Bouwmeester, Harro, Fischer, Rainer, Schillberg, Stefan

“…We compared the ability of different plant-based expression platforms to produce geraniol, a key metabolite in the monoterpenoid branch of the terpenoid indole…”
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Differential patterns of dehydroabietic acid biotransformation by Nicotiana tabacum and Catharanthus roseus cells by Häkkinen, Suvi T., Lackman, Petri, Nygrén, Heli, Oksman-Caldentey, Kirsi-Marja, Maaheimo, Hannu, Rischer, Heiko

“…► Plant cells were used in bioconversion studies of dehydroabietic acid (DHA). ► Metabolic changes in plant cells during bioconversion were monitored by NMR. ►…”
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Functional characterisation of genes involved in pyridine alkaloid biosynthesis in tobacco by Häkkinen, Suvi T., Tilleman, Sofie, Šwiątek, Agnieszka, De Sutter, Valerie, Rischer, Heiko, Vanhoutte, Isabelle, Van Onckelen, Harry, Hilson, Pierre, Inzé, Dirk, Oksman-Caldentey, Kirsi-Marja, Goossens, Alain

“…Potential catalysers of tobacco pyridine metabolism can be discovered by functional genomics-based analysis of a Nicotiana tabacum gene platform, established…”
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Enhanced secretion of tropane alkaloids in Nicotiana tabacum hairy roots expressing heterologous hyoscyamine-6β-hydroxylase by Häkkinen, Suvi T., Moyano, Elisabeth, Cusidó, Rosa M., Palazón, Javier, Piñol, M. Teresa, Oksman-Caldentey, Kirsi-Marja

“…Hyoscyamine-6β-hydroxylase (H6H; EC 1.14.11.11) catalyses oxidative reactions in the biosynthetic pathway leading from hyoscyamine to the more pharmaceutically…”
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Secretion of secondary metabolites by ATP-binding cassette transporters in plant cell suspension cultures by Goossens, A, Hakkinen, S.T, Laakso, I, Oksman-Caldentey, K.M, Inze, D

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