Search Results - "Häggblad, Johan"

Comparison of the Ligand Binding Specificity and Transcript Tissue Distribution of Estrogen Receptors α and β by Kuiper, George G. J. M, Carlsson, Bo, Grandien, Kaj, Enmark, Eva, Häggblad, Johan, Nilsson, Stefan, Gustafsson, Jan-Åke

“…The rat estrogen receptor (ER) exists as two subtypes, ERα and ERβ, which differ in the C-terminal ligand binding domain and in the N-terminal transactivation…”
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Quantitative Determination of DNA-Binding Parameters for the Human Estrogen Receptor in a Solid-Phase, Nonseparation Assay by Carlsson, Bo, Häggblad, Johan

“…Binding of transcription factors to specific sequences of DNA has been studied for more than a decade and has become a very productive field of research. This…”
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Restorative effects of platelet derived growth factor-BB in rodent models of Parkinson's disease by Zachrisson, Olof, Zhao, Ming, Andersson, Annica, Dannaeus, Karin, Häggblad, Johan, Isacson, Ruben, Nielsen, Elisabet, Patrone, Cesare, Rönnholm, Harriet, Wikstrom, Lilian, Delfani, Kristofer, McCormack, Alison L, Palmer, Theo, Di Monte, Donato A, Hill, Michael P, Janson Lang, Ann Marie, Haegerstrand, Anders

“…Parkinson's disease is characterized by motor deficits caused by loss of midbrain dopaminergic neurons. Neurotrophic factors and cell transplantation have…”
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Desethylamiodarone Prolongation of Cardiac Repolarization is Dependent on Gene Expression: A Novel Antiarrhythmic Mechanism by Drvota, Viktor, Blange, Irina, Häggblad, Johan, Sylvén, Christer

“…Desethylamiodarone (DEA) is the major metabolite of amiodarone and has similar electrophysiologic effects with prolongation of the repolarization that is…”
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Scintillating microtitration plates in model experiments measuring hormone and DNA binding to the human thyroid hormone receptor by Carlsson, Bo, Häggblad, Johan

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Evidence for the presence of functional thyrotropin receptor in cardiac muscle by Drvota, V, Janson, A, Norman, C, Sylvén, C, Häggblad, J, Brönnegård, M, Marcus, C

“…There is increasing evidence that the membrane-bound thyrotropin receptor (TSHR) may be mediating clinically important direct effects of thyrotropin (TSH) and…”
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Equilibrium hormone binding to human estrogen receptors in highly diluted cell extracts is non-cooperative and has a Kd of approximately 10 pM by Salomonsson, M, Carlsson, B, Häggblad, J

“…It is generally accepted that the Kd for hormone binding to estrogen receptors in extracts ranges between 0.1-1 nM and that binding displays positive…”
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Application of a Novel Method for the Comparison of DNA Binding Parameters of the Two Human Thyroid Hormone Receptor Subtypes hTRα1 and hTRβ1 by Carlsson, Bo, Ahola, Harri, Häggblad, Johan

“…Abstract DNA-binding characteristics of the two human thyroid hormone receptors α1 and β1 (hTRα1 and hTRβ1) were studied by applying the recently developed…”
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P2-purinoceptor-stimulated phosphoinositide turnover in chick myotubes calcium mobilization and the role of guanyl nucleotide-binding proteins by Häggblad, Johan, Heilbronn, Edith

“…ATP, a trigger of P2-purinoceptor-mediated polyphosphoinositide (PI) turnover in cultured myotubes, increased cytosolic calcium levels in a time- and…”
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The human estrogen receptor hormone binding domain dimerizes independently of ligand activation by Salomonsson, M, Häggblad, J, O'Malley, B W, Sitbon, G M

“…High level expression of biochemically active human estrogen receptor hormone binding domain (hER-HBD) was achieved using a Saccharomyces cerevisiae expression…”
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Application of a novel method for the comparison of DNA binding parameters of the two human thyroid hormone receptor subtypes hTR alpha 1 and hTR beta 1 by Carlsson, B, Ahola, H, Häggblad, J

“…DNA-binding characteristics of the two human thyroid hormone receptors alpha 1 and beta 1 (hTR alpha 1 and hTR beta 1) were studied by applying the recently…”
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Scintillating microtitration plates, a platform for hormone and DNA binding assays. Model experiments with the human estrogen receptor by Häggblad, Johan, Carlsson, Bo, Kivelä, Petri, Siitari, Harri

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Externally applied adenosine-5'-triphosphate causes inositol triphosphate accumulation in cultured chick myotubes by Häggblad, J, Heilbronn, E

“…In striated muscle, adenosine-5'-triphosphate (ATP) potentiates the responses to acetylcholine. The underlying biochemical events are unknown. Here we report…”
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Receptor-triggered polyphosphoinositide turnover produces less cytosolic free calcium in cultured dysgenic myotubes than in normal myotubes by Tassin, A M, Häggblad, J, Heilbronn, E

“…Myotubes prepared from mice with muscular dysgenesis (mdg) were used to further elucidate the putative role of inositol triphosphate (InsP3) in…”
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ATP-induced cation influx in myotubes is additive to cholinergic agonist action by Häggblad, J, Eriksson, H, Heilbronn, E

“…Using biochemical methods, ATP was shown to induce an inward flux of 86Rb into cultured chick myotubes. A biphasic dose-response curve was observed, the first…”
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Basal and ATP-stimulated phosphoinositol metabolism in fusing rat skeletal muscle cells in culture by Keresztes, M, Häggblad, J, Heilbronn, E

“…A considerable rise in inositol phosphates was observed at the beginning of myoblast fusion. Extracellular ATP, through P2-purinergic receptors, induced…”
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