Search Results - "HÄNGGI, Daniel"

Inflammation and Anti-Inflammatory Targets after Aneurysmal Subarachnoid Hemorrhage by Muhammad, Sajjad, Hänggi, Daniel

“…Aneurysmal subarachnoid hemorrhage (aSAH), with a crude worldwide incidence of around 7 [...]…”
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Practical implementation of DNA methylation and copy-number-based CNS tumor diagnostics: the Heidelberg experience by Capper, David, Stichel, Damian, Sahm, Felix, Jones, David T. W., Schrimpf, Daniel, Sill, Martin, Schmid, Simone, Hovestadt, Volker, Reuss, David E., Koelsche, Christian, Reinhardt, Annekathrin, Wefers, Annika K., Huang, Kristin, Sievers, Philipp, Ebrahimi, Azadeh, Schöler, Anne, Teichmann, Daniel, Koch, Arend, Hänggi, Daniel, Unterberg, Andreas, Platten, Michael, Wick, Wolfgang, Witt, Olaf, Milde, Till, Korshunov, Andrey, Pfister, Stefan M., von Deimling, Andreas

“…Recently, we described a machine learning approach for classification of central nervous system tumors based on the analysis of genome-wide DNA methylation…”
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Nimodipine Reappraised: An Old Drug With a Future by Carlson, Andrew P., Hänggi, Daniel, Macdonald, Robert L., Shuttleworth, Claude W.

“…Nimodipine is a dihydropyridine calcium channel antagonist that blocks the flux of extracellular calcium through L-type, voltage-gated calcium channels. While…”
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Would they do it again? Final treatment decisions in malignant brain tumour patients—a caregiver’s perspective by Rapp, Marion, von Sass, Christiane, Backhaus, Clara, Hänggi, Daniel, Kamp, Marcel Alexander, Sabel, Michael

“…Purpose Overall survival of malignant brain tumour patients has significantly been increased over the last years. However, therapy remains palliative, and side…”
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Janus Faced HMGB1 and Post-Aneurysmal Subarachnoid Hemorrhage (aSAH) Inflammation by Chaudhry, Shafqat Rasul, Shafique, Sumaira, Sajjad, Saba, Hänggi, Daniel, Muhammad, Sajjad

“…Aneurysmal subarachnoid hemorrhage (aSAH), resulting majorly from the rupture of intracranial aneurysms, is a potentially devastating disease with high…”
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Methylation-based classification of benign and malignant peripheral nerve sheath tumors by Röhrich, Manuel, Koelsche, Christian, Schrimpf, Daniel, Capper, David, Sahm, Felix, Kratz, Annekathrin, Reuss, Jana, Hovestadt, Volker, Jones, David T. W., Bewerunge-Hudler, Melanie, Becker, Albert, Weis, Joachim, Mawrin, Christian, Mittelbronn, Michel, Perry, Arie, Mautner, Victor-Felix, Mechtersheimer, Gunhild, Hartmann, Christian, Okuducu, Ali Fuat, Arp, Mirko, Seiz-Rosenhagen, Marcel, Hänggi, Daniel, Heim, Stefanie, Paulus, Werner, Schittenhelm, Jens, Ahmadi, Rezvan, Herold-Mende, Christel, Unterberg, Andreas, Pfister, Stefan M., von Deimling, Andreas, Reuss, David E.

“…The vast majority of peripheral nerve sheath tumors derive from the Schwann cell lineage and comprise diverse histological entities ranging from benign…”
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Molecular features of glioblastomas in long-term survivors compared to short-term survivors-a matched-pair analysis by Sommerlath, Vivien N, Buergy, Daniel, Etminan, Nima, Brehmer, Stefanie, Reuss, David, Sarria, Gustavo R, Guiot, Marie-Christin, Hänggi, Daniel, Wenz, Frederik, Petrecca, Kevin, Giordano, Frank A

“…Although glioblastoma (GB) is associated with a devastating prognosis, a small proportion of patients achieve long-term survival rates. We herein present a…”
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Role of Adaptor Protein Myeloid Differentiation 88 (MyD88) in Post-Subarachnoid Hemorrhage Inflammation: A Systematic Review by Ahmed, Hammad, Khan, Mahtab Ahmad, Kahlert, Ulf Dietrich, Niemelä, Mika, Hänggi, Daniel, Chaudhry, Shafqat Rasul, Muhammad, Sajjad

“…Myeloid differentiation 88 (MyD88) is a well-established inflammatory adaptor protein. It is one of the essential downstream proteins of the toll-like receptor…”
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Mutational patterns and regulatory networks in epigenetic subgroups of meningioma by Paramasivam, Nagarajan, Hübschmann, Daniel, Toprak, Umut H, Ishaque, Naveed, Neidert, Marian, Schrimpf, Daniel, Stichel, Damian, Reuss, David, Sievers, Philipp, Reinhardt, Annekathrin, Wefers, Annika K., Jones, David T. W., Gu, Zuguang, Werner, Johannes, Uhrig, Sebastian, Wirsching, Hans-Georg, Schick, Matthias, Bewerunge-Hudler, Melanie, Beck, Katja, Brehmer, Stephanie, Urbschat, Steffi, Seiz-Rosenhagen, Marcel, Hänggi, Daniel, Herold-Mende, Christel, Ketter, Ralf, Eils, Roland, Ram, Zvi, Pfister, Stefan M., Wick, Wolfgang, Weller, Michael, Grossmann, Rachel, von Deimling, Andreas, Schlesner, Matthias, Sahm, Felix

“…DNA methylation patterns delineate clinically relevant subgroups of meningioma. We previously established the six meningioma methylation classes (MC) benign…”
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Critical Care Management of Patients Following Aneurysmal Subarachnoid Hemorrhage: Recommendations from the Neurocritical Care Society’s Multidisciplinary Consensus Conference by Diringer, Michael N., Bleck, Thomas P., Claude Hemphill, J., Menon, David, Shutter, Lori, Vespa, Paul, Bruder, Nicolas, Connolly, E. Sander, Citerio, Giuseppe, Gress, Daryl, Hänggi, Daniel, Hoh, Brian L., Lanzino, Giuseppe, Le Roux, Peter, Rabinstein, Alejandro, Schmutzhard, Erich, Stocchetti, Nino, Suarez, Jose I., Treggiari, Miriam, Tseng, Ming-Yuan, Vergouwen, Mervyn D. I., Wolf, Stefan, Zipfel, Gregory

“…Subarachnoid hemorrhage (SAH) is an acute cerebrovascular event which can have devastating effects on the central nervous system as well as a profound impact…”
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SARS-CoV-2 infection increases risk of intracranial hemorrhage by Hawsawi, Zuhair, Khan, Dilaware, Fischer, Igor, Cornelius, Jan Frederick, Hänggi, Daniel, Muhammad, Sajjad

“…SARS-CoV-2 virus infection causes a dysbalanced and severe inflammatory response, including hypercytokinemia and immunodepression. Systemic inflammation…”
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Elevated Systemic IL-10 Levels Indicate Immunodepression Leading to Nosocomial Infections after Aneurysmal Subarachnoid Hemorrhage (SAH) in Patients by Chaudhry, Shafqat Rasul, Kahlert, Ulf Dietrich, Kinfe, Thomas Mehari, Lamprecht, Alf, Niemelä, Mika, Hänggi, Daniel, Muhammad, Sajjad

“…Aneurysmal subarachnoid hemorrhage (SAH) is a highly complex disease with very high mortality and morbidity. About one-third of SAH patients suffer from…”
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Targeting High Mobility Group Box 1 in Subarachnoid Hemorrhage: A Systematic Review by Muhammad, Sajjad, Chaudhry, Shafqat Rasul, Kahlert, Ulf Dietrich, Lehecka, Martin, Korja, Miikka, Niemelä, Mika, Hänggi, Daniel

“…Aneurysmal subarachnoid hemorrhage (aSAH) is a complex and potentially deadly disease. Neurosurgical clipping or endovascular coiling can successfully…”
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Randomized, Open-Label, Phase 1/2a Study to Determine the Maximum Tolerated Dose of Intraventricular Sustained Release Nimodipine for Subarachnoid Hemorrhage (NEWTON [Nimodipine Microparticles to Enhance Recovery While Reducing Toxicity After Subarachnoid Hemorrhage]) by Hänggi, Daniel, Etminan, Nima, Aldrich, Francois, Steiger, Hans Jakob, Mayer, Stephan A, Diringer, Michael N, Hoh, Brian L, Mocco, J, Faleck, Herbert J, Macdonald, R Loch

“…BACKGROUND AND PURPOSE—We conducted a randomized, open-label, phase 1/2a, dose-escalation study of intraventricular sustained-release nimodipine (EG-1962) to…”
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Does positive MGMT methylation outbalance the limitation of subtotal resection in glioblastoma IDH-wildtype patients? by Mareike, Müller, Franziska, Staub-Bartelt, Julia, Ehrmann, Daniel, Hänggi, Michael, Sabel, Jörg, Felsberg, Marion, Rapp

“…Background The impact on survival of complete resection (CR) in patients with malignant glioma and MGMT promoter methylation on adjuvant therapy strategies has…”
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Virtual reality guided focused Sylvian approach for clipping unruptured middle cerebral artery aneurysms by Zhang, Rui, Hänggi, Daniel, Köskemeier, Pia, Muhammad, Sajjad

“…The increasing prevalence of unruptured intracranial aneurysms, detected through advanced brain imaging, necessitates a cautious approach to surgical…”
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Differential polarization and activation dynamics of systemic T helper cell subsets after aneurysmal subarachnoid hemorrhage (SAH) and during post-SAH complications by Chaudhry, Shafqat Rasul, Kahlert, Ulf Dietrich, Kinfe, Thomas Mehari, Endl, Elmar, Dolf, Andreas, Niemelä, Mika, Hänggi, Daniel, Muhammad, Sajjad

“…Aneurysmal subarachnoid hemorrhage (SAH) is associated with high morbidity and mortality. Devastating post-SAH complications, such as cerebral vasospasm (CVS),…”
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Barrel Stave Osteotomy Decompression for Acute Brain Injury in Infants: Technical Note by Beez, Thomas, Munoz-Bendix, Christopher, Hänggi, Daniel, Beseoglu, Kerim, Cornelius, Jan F.

“…Decompressive craniectomy (DC) is rarely required in infants, but when performed several aspects should be considered: These youngest patients are vulnerable…”
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Impact of Anticipated Awake Surgery on Psychooncological Distress in Brain Tumor Patients by Staub-Bartelt, Franziska, Radtke, Oliver, Hänggi, Daniel, Sabel, Michael, Rapp, Marion

“…Brain tumor patients present high rates of distress, anxiety, and depression, in particular perioperatively. For resection of eloquent located cerebral…”
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Effect of Locally Delivered Nimodipine Microparticles on Spreading Depolarization in Aneurysmal Subarachnoid Hemorrhage by Carlson, Andrew P., Alchbli, Amal, Hänggi, Daniel, Macdonald, R. Loch, Shuttleworth, C. William

“…Background Recurrent spreading depolarizations (SDs) occur in patients after aneurysmal subarachnoid hemorrhage (aSAH), resulting in metabolic stress to brain…”
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