Search Results - "HÄNELT, Inga"

Regulation of lipid saturation without sensing membrane fluidity by Ballweg, Stephanie, Sezgin, Erdinc, Doktorova, Milka, Covino, Roberto, Reinhard, John, Wunnicke, Dorith, Hänelt, Inga, Levental, Ilya, Hummer, Gerhard, Ernst, Robert

“…Cells maintain membrane fluidity by regulating lipid saturation, but the molecular mechanisms of this homeoviscous adaptation remain poorly understood. We have…”
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Activation of the Unfolded Protein Response by Lipid Bilayer Stress by Halbleib, Kristina, Pesek, Kristina, Covino, Roberto, Hofbauer, Harald F., Wunnicke, Dorith, Hänelt, Inga, Hummer, Gerhard, Ernst, Robert

“…The unfolded protein response (UPR) is a conserved homeostatic program that is activated by misfolded proteins in the lumen of the endoplasmic reticulum (ER)…”
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Structural basis of proton-coupled potassium transport in the KUP family by Tascón, Igor, Sousa, Joana S., Corey, Robin A., Mills, Deryck J., Griwatz, David, Aumüller, Nadine, Mikusevic, Vedrana, Stansfeld, Phillip J., Vonck, Janet, Hänelt, Inga

“…Potassium homeostasis is vital for all organisms, but is challenging in single-celled organisms like bacteria and yeast and immobile organisms like plants that…”
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Unsynchronised subunit motion in single trimeric sodium-coupled aspartate transporters by Erkens, Guus B., Hänelt, Inga, Goudsmits, Joris M. H., Slotboom, Dirk Jan, van Oijen, Antoine M.

“…Glutamate transporters are integral membrane proteins that facilitate neurotransmitter uptake from the synaptic cleft into the cytoplasm of glial cells and…”
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Deciphering ion transport and ATPase coupling in the intersubunit tunnel of KdpFABC by Silberberg, Jakob M., Corey, Robin A., Hielkema, Lisa, Stock, Charlott, Stansfeld, Phillip J., Paulino, Cristina, Hänelt, Inga

“…KdpFABC, a high-affinity K + pump, combines the ion channel KdpA and the P-type ATPase KdpB to secure survival at K + limitation. Here, we apply a combination…”
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Low Affinity and Slow Na+ Binding Precedes High Affinity Aspartate Binding in the Secondary-active Transporter GltPh by Hänelt, Inga, Jensen, Sonja, Wunnicke, Dorith, Slotboom, Dirk Jan

“…GltPh from Pyrococcus horikoshii is a homotrimeric Na+-coupled aspartate transporter. It belongs to the widespread family of glutamate transporters, which also…”
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Cyclic di-AMP traps proton-coupled K+ transporters of the KUP family in an inward-occluded conformation by Fuss, Michael F., Wieferig, Jan-Philip, Corey, Robin A., Hellmich, Yvonne, Tascón, Igor, Sousa, Joana S., Stansfeld, Phillip J., Vonck, Janet, Hänelt, Inga

“…Cyclic di-AMP is the only known essential second messenger in bacteria and archaea, regulating different proteins indispensable for numerous physiological…”
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Arabidopsis HAK5 under low K+ availability operates as PMF powered high-affinity K+ transporter by Maierhofer, Tobias, Scherzer, Sönke, Carpaneto, Armando, Müller, Thomas D., Pardo, Jose M., Hänelt, Inga, Geiger, Dietmar, Hedrich, Rainer

“…Plants can survive in soils of low micromolar potassium (K + ) concentrations. Root K + intake is accomplished by the K + channel AKT1 and KUP/HAK/KT type…”
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KdpD is a tandem serine histidine kinase that controls K+ pump KdpFABC transcriptionally and post-translationally by Silberberg, Jakob M., Ketter, Sophie, Böhm, Paul J. N., Jordan, Kristin, Wittenberg, Marcel, Grass, Julia, Hänelt, Inga

“…Two-component systems, consisting of a histidine kinase and a response regulator, serve signal transduction in bacteria, often regulating transcription in…”
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Inhibited KdpFABC transitions into an E1 off-cycle state by Silberberg, Jakob M, Stock, Charlott, Hielkema, Lisa, Corey, Robin A, Rheinberger, Jan, Wunnicke, Dorith, Dubach, Victor R A, Stansfeld, Phillip J, Hänelt, Inga, Paulino, Cristina

“…KdpFABC is a high-affinity prokaryotic K uptake system that forms a functional chimera between a channel-like subunit (KdpA) and a P-type ATPase (KdpB). At…”
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Helical jackknives control the gates of the double-pore K + uptake system KtrAB by Diskowski, Marina, Mehdipour, Ahmad Reza, Wunnicke, Dorith, Mills, Deryck J, Mikusevic, Vedrana, Bärland, Natalie, Hoffmann, Jan, Morgner, Nina, Steinhoff, Heinz-Jürgen, Hummer, Gerhard, Vonck, Janet, Hänelt, Inga

“…Ion channel gating is essential for cellular homeostasis and is tightly controlled. In some eukaryotic and most bacterial ligand-gated K channels, RCK domains…”
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Molecular Mechanisms of Adaptation of the Moderately Halophilic Bacterium Halobacillis halophilus to Its Environment by Hänelt, Inga, Müller, Volker

“…The capability of osmoadaptation is a prerequisite of organisms that live in an environment with changing salinities. Halobacillus halophilus is a moderately…”
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Substrate-Induced Conformational Changes in the S-Component ThiT from an Energy Coupling Factor Transporter by Majsnerowska, Maria, Hänelt, Inga, Wunnicke, Dorith, Schäfer, Lars V., Steinhoff, Heinz-Jürgen, Slotboom, Dirk Jan

“…Energy coupling factor (ECF) transporters are a recently discovered class of ABC transporters that mediate vitamin uptake in prokaryotes. Characteristic for…”
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Discovery of a Small Molecule Activator of Slack (Kcnt1) Potassium Channels That Significantly Reduces Scratching in Mouse Models of Histamine‐Independent and Chronic Itch by Balzulat, Annika, Zhu, W. Felix, Flauaus, Cathrin, Hernandez‐Olmos, Victor, Heering, Jan, Sethumadhavan, Sunesh, Dubiel, Mariam, Frank, Annika, Menge, Amelie, Hebchen, Maureen, Metzner, Katharina, Lu, Ruirui, Lukowski, Robert, Ruth, Peter, Knapp, Stefan, Müller, Susanne, Steinhilber, Dieter, Hänelt, Inga, Stark, Holger, Proschak, Ewgenij, Schmidtko, Achim

“…Various disorders are accompanied by histamine‐independent itching, which is often resistant to the currently available therapies. Here, it is reported that…”
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Wie Bakterien die Aufnahme von Kaliumionen regulieren by Silberberg, Jakob M., Hänelt, Inga

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Bioenergetics of the Moderately Halophilic Bacterium Halobacillus halophilus: Composition and Regulation of the Respiratory Chain by PADE, Nadin, KÖCHER, Saskia, ROESSLER, Markus, HÄNELT, Inga, MÜLLER, Volker

“…Classifications Services AEM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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KtrB, a member of the superfamily of K + transporters by Hänelt, Inga, Tholema, Nancy, Kröning, Nadine, Vor der Brüggen, Marc, Wunnicke, Dorith, Bakker, Evert P.

“…KtrB is the K +-translocating subunit of the K +-uptake system KtrAB from bacteria. It is a member of the superfamily of K + transporters (SKT proteins) with…”
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How RCK domains regulate gating of K+ channels by Schrecker, Marina, Wunnicke, Dorith, Hänelt, Inga

“…Potassium channels play a crucial role in the physiology of all living organisms. They maintain the membrane potential and are involved in electrical…”
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Crystal structure of a substrate-free aspartate transporter by Jensen, Sonja, Guskov, Albert, Rempel, Stephan, Hänelt, Inga, Slotboom, Dirk Jan

“…Archaeal glutamate transporter homologs catalyze the coupled uptake of aspartate and sodium ions. A new crystal structure of Glt Tk from Thermococcus…”
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Membrane Protein Solubilization and Quality Control: An Example of a Primary Active Transporter by Stock, Charlott, Hänelt, Inga

“…When purifying a membrane protein, finding a detergent for solubilization is one of the first steps to master. Ideally, only little time is invested to…”
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