Search Results - "Gypas, Foivos"

Nanopore sequencing reveals endogenous NMD-targeted isoforms in human cells by Karousis, Evangelos D, Gypas, Foivos, Zavolan, Mihaela, Mühlemann, Oliver

“…Nonsense-mediated mRNA decay (NMD) is a eukaryotic, translation-dependent degradation pathway that targets mRNAs with premature termination codons and also…”
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Aberrant interaction of FUS with the U1 snRNA provides a molecular mechanism of FUS induced amyotrophic lateral sclerosis by Jutzi, Daniel, Campagne, Sébastien, Schmidt, Ralf, Reber, Stefan, Mechtersheimer, Jonas, Gypas, Foivos, Schweingruber, Christoph, Colombo, Martino, von Schroetter, Christine, Loughlin, Fionna E., Devoy, Anny, Hedlund, Eva, Zavolan, Mihaela, Allain, Frédéric H.-T., Ruepp, Marc-David

“…Mutations in the RNA-binding protein Fused in Sarcoma (FUS) cause early-onset amyotrophic lateral sclerosis (ALS). However, a detailed understanding of central…”
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Comparative assessment of methods for the computational inference of transcript isoform abundance from RNA-seq data by Kanitz, Alexander, Gypas, Foivos, Gruber, Andreas J, Gruber, Andreas R, Martin, Georges, Zavolan, Mihaela

“…Understanding the regulation of gene expression, including transcription start site usage, alternative splicing, and polyadenylation, requires accurate…”
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Protease-mediated processing of Argonaute proteins controls small RNA association by Gudipati, Rajani Kanth, Braun, Kathrin, Gypas, Foivos, Hess, Daniel, Schreier, Jan, Carl, Sarah H., Ketting, René F., Großhans, Helge

“…Small RNA pathways defend the germlines of animals against selfish genetic elements, yet pathway activities need to be contained to prevent silencing of self…”
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mpMoRFsDB: a database of molecular recognition features in membrane proteins by Gypas, Foivos, Tsaousis, Georgios N, Hamodrakas, Stavros J

“…Molecular recognition features (MoRFs) are small, intrinsically disordered regions in proteins that undergo a disorder-to-order transition on binding to their…”
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Terminal exon characterization with TECtool reveals an abundance of cell-specific isoforms by Gruber, Andreas J., Gypas, Foivos, Riba, Andrea, Schmidt, Ralf, Zavolan, Mihaela

“…Sequencing of RNA 3′ ends has uncovered numerous sites that do not correspond to the termination sites of known transcripts. Through their 3′ untranslated…”
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High-throughput identification of C/D box snoRNA targets with CLIP and RiboMeth-seq by Gumienny, Rafal, Jedlinski, Dominik J, Schmidt, Alexander, Gypas, Foivos, Martin, Georges, Vina-Vilaseca, Arnau, Zavolan, Mihaela

“…High-throughput sequencing has greatly facilitated the discovery of long and short non-coding RNAs (ncRNAs), which frequently guide ribonucleoprotein complexes…”
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A specific type of Argonaute phosphorylation regulates binding to microRNAs during C. elegans development by Quévillon Huberdeau, Miguel, Shah, Vivek Nilesh, Nahar, Smita, Neumeier, Julia, Houle, François, Bruckmann, Astrid, Gypas, Foivos, Nakanishi, Kotaro, Großhans, Helge, Meister, Gunter, Simard, Martin J.

“…Argonaute proteins are at the core of the microRNA-mediated gene silencing pathway essential for animals. In C. elegans, the microRNA-specific Argonautes ALG-1…”
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Gene Expression Signatures of a Preclinical Mouse Model during Colorectal Cancer Progression under Low-Dose Metronomic Chemotherapy by Ho-Xuan, Hung, Lehmann, Gerhard, Glazar, Petar, Gypas, Foivos, Eichner, Norbert, Heizler, Kevin, Schlitt, Hans Jürgen, Zavolan, Mihaela, Rajewsky, Nikolaus, Meister, Gunter, Hackl, Christina

“…Understanding the molecular signatures of colorectal cancer progression under chemotherapeutic treatment will be crucial for the success of future therapy…”
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ZARP: A user-friendly and versatile RNA-seq analysis workflow [version 1; peer review: awaiting peer review] by Katsantoni, Maria, Gypas, Foivos, Herrmann, Christina J, Burri, Dominik, Bąk, Maciej, Iborra, Paula, Agarwal, Krish, Ataman, Meriç, Balajti, Máté, Pozzan, Noè, Schlusser, Niels, Moon, Youngbin, Mironov, Aleksei, Börsch, Anastasiya, Zavolan, Mihaela, Kanitz, Alexander

“…Background RNA sequencing (RNA-seq) is a widely used technique in many scientific studies. Given the plethora of models and software packages that have been…”
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A disease annotation study of gene signatures in a breast cancer microarray dataset by Gypas, F., Bei, E. S., Zervakis, M., Sfakianakis, S.

“…Breast cancer is a complex disease with heterogeneity between patients regarding prognosis and treatment response. Recent progress in advanced molecular…”
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