Search Results - "Gyongyosi, Benedek"

Pharmacological Inhibition of CCR2/5 Signaling Prevents and Reverses Alcohol‐Induced Liver Damage, Steatosis, and Inflammation in Mice by Ambade, Aditya, Lowe, Patrick, Kodys, Karen, Catalano, Donna, Gyongyosi, Benedek, Cho, Yeonhee, Iracheta‐Vellve, Arvin, Adejumo, Adeyinka, Saha, Banishree, Calenda, Charles, Mehta, Jeeval, Lefebvre, Eric, Vig, Pamela, Szabo, Gyongyi

“…Kupffer cell and macrophage (MØ) activation contributes to steatosis, inflammation, and fibrosis in alcoholic liver disease (ALD). We found increased frequency…”
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Recovery of ethanol-induced Akkermansia muciniphila depletion ameliorates alcoholic liver disease by Grander, Christoph, Adolph, Timon E, Wieser, Verena, Lowe, Patrick, Wrzosek, Laura, Gyongyosi, Benedek, Ward, Doyle V, Grabherr, Felix, Gerner, Romana R, Pfister, Alexandra, Enrich, Barbara, Ciocan, Dragos, Macheiner, Sophie, Mayr, Lisa, Drach, Matthias, Moser, Patrizia, Moschen, Alexander R, Perlemuter, Gabriel, Szabo, Gyongyi, Cassard, Anne Marie, Tilg, Herbert

“…Alcoholic liver disease (ALD) is a global health problem with limited therapeutic options. Intestinal barrier integrity and the microbiota modulate…”
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Abnormal neutrophil traps and impaired efferocytosis contribute to liver injury and sepsis severity after binge alcohol use by Bukong, Terence Ndonyi, Cho, Yeonhee, Iracheta-Vellve, Arvin, Saha, Banishree, Lowe, Patrick, Adejumo, Adeyinka, Furi, Istvan, Ambade, Aditya, Gyongyosi, Benedek, Catalano, Donna, Kodys, Karen, Szabo, Gyongyi

“…[Display omitted] •Alcohol treatment induces spontaneous neutrophil extracellular trap (NET) formation.•Alcohol impairs further NET release by the same…”
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Reduced gut microbiome protects from alcohol-induced neuroinflammation and alters intestinal and brain inflammasome expression by Lowe, Patrick P, Gyongyosi, Benedek, Satishchandran, Abhishek, Iracheta-Vellve, Arvin, Cho, Yeonhee, Ambade, Aditya, Szabo, Gyongyi

“…The end-organ effects of alcohol span throughout the entire body, from the gastrointestinal tract to the central nervous system (CNS). In the intestine,…”
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Endoplasmic Reticulum Stress-induced Hepatocellular Death Pathways Mediate Liver Injury and Fibrosis via Stimulator of Interferon Genes by Iracheta-Vellve, Arvin, Petrasek, Jan, Gyongyosi, Benedek, Satishchandran, Abhishek, Lowe, Patrick, Kodys, Karen, Catalano, Donna, Calenda, Charles D., Kurt-Jones, Evelyn A., Fitzgerald, Katherine A., Szabo, Gyongyi

“…Fibrosis, driven by inflammation, marks the transition from benign to progressive stages of chronic liver diseases. Although inflammation promotes…”
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MicroRNA 122, Regulated by GRLH2, Protects Livers of Mice and Patients From Ethanol-Induced Liver Disease by Satishchandran, Abhishek, Ambade, Aditya, Rao, Sitara, Hsueh, Ying-Chao, Iracheta-Vellve, Arvin, Tornai, David, Lowe, Patrick, Gyongyosi, Benedek, Li, Jia, Catalano, Donna, Zhong, Li, Kodys, Karen, Xie, Jun, Bala, Shashi, Gao, Guangping, Szabo, Gyongyi

“…Chronic, excessive alcohol consumption leads to alcoholic liver disease (ALD) characterized by steatosis, inflammation, and eventually cirrhosis. The…”
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Adult mouse model of early hepatocellular carcinoma promoted by alcoholic liver disease by Ambade, Aditya, Satishchandran, Abhishek, Gyongyosi, Benedek, Lowe, Patrick, Szabo, Gyongyi

“…AIM: To establish a mouse model of alcohol-driven hepatocellular carcinoma(HCC) that develops in livers with alcoholic liver disease(ALD).METHODS: Adult…”
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Inhibition of sterile danger signals, uric acid and ATP, prevents inflammasome activation and protects from alcoholic steatohepatitis in mice by Iracheta-Vellve, Arvin, Petrasek, Jan, Satishchandran, Abhishek, Gyongyosi, Benedek, Saha, Banishree, Kodys, Karen, Fitzgerald, Katherine A, Kurt-Jones, Evelyn A, Szabo, Gyongyi

“…Graphical abstract…”
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Alcohol-related changes in the intestinal microbiome influence neutrophil infiltration, inflammation and steatosis in early alcoholic hepatitis in mice by Lowe, Patrick P, Gyongyosi, Benedek, Satishchandran, Abhishek, Iracheta-Vellve, Arvin, Ambade, Aditya, Kodys, Karen, Catalano, Donna, Ward, Doyle V, Szabo, Gyongyi

“…Alcohol-induced intestinal dysbiosis disrupts homeostatic gut-liver axis function and is essential in the development of alcoholic liver disease. Here, we…”
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Chronic alcohol-induced neuroinflammation involves CCR2/5-dependent peripheral macrophage infiltration and microglia alterations by Lowe, Patrick P, Morel, Caroline, Ambade, Aditya, Iracheta-Vellve, Arvin, Kwiatkowski, Erica, Satishchandran, Abhishek, Furi, Istvan, Cho, Yeonhee, Gyongyosi, Benedek, Catalano, Donna, Lefebvre, Eric, Fischer, Laurent, Seyedkazemi, Star, Schafer, Dorothy P, Szabo, Gyongyi

“…Chronic alcohol consumption is associated with neuroinflammation, neuronal damage, and behavioral alterations including addiction. Alcohol-induced…”
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Correction: Alcohol-related changes in the intestinal microbiome influence neutrophil infiltration, inflammation and steatosis in early alcoholic hepatitis in mice by Lowe, Patrick P, Gyongyosi, Benedek, Satishchandran, Abhishek, Iracheta-Vellve, Arvin, Ambade, Aditya, Cho, Yeonhee, Kodys, Karen, Catalano, Donna, Ward, Doyle V, Szabo, Gyongyi

“…[This corrects the article DOI: 10.1371/journal.pone.0174544.]…”
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Development and Initial Testing of a Modified UroVysion-Based Fluorescence In Situ Hybridization Score for Prediction of Progression in Bladder Cancer by Kocsmár, Ildikó, Pajor, Gábor, Gyöngyösi, Benedek, Székely, Eszter, Varga, Márton, Kocsmár, Éva, Kenessey, István, Beöthe, Tamás, Süle, Norbert, Majoros, Attila, Szendrői, Attila, Nyírády, Péter, Kiss, András, Riesz, Péter, Lotz, Gábor

“…Abstract Objectives Our aim was to predict progression of non-muscle-invasive bladder urothelial carcinomas (NMIUCs) into muscle-invasive disease by assessing…”
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MicroRNA Expression in Focal Nodular Hyperplasia in Comparison with Cirrhosis and Hepatocellular Carcinoma by Lendvai, Gábor, Szekerczés, Tímea, Gyöngyösi, Benedek, Schlachter, Krisztina, Kontsek, Endre, Pesti, Adrián, Patonai, Attila, Werling, Klára, Kovalszky, Ilona, Schaff, Zsuzsa, Kiss, András

“…The liver disease focal nodular hyperplasia (FNH) has several histological features that resemble hepatic cirrhosis. Since cirrhosis may develop further into…”
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HunCRC: annotated pathological slides to enhance deep learning applications in colorectal cancer screening by Pataki, Bálint Ármin, Olar, Alex, Ribli, Dezső, Pesti, Adrián, Kontsek, Endre, Gyöngyösi, Benedek, Bilecz, Ágnes, Kovács, Tekla, Kovács, Kristóf Attila, Kramer, Zsófia, Kiss, András, Szócska, Miklós, Pollner, Péter, Csabai, István

“…Histopathology is the gold standard method for staging and grading human tumors and provides critical information for the oncoteam’s decision making…”
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Pretreatment MicroRNA Level and Outcome in Sorafenib-treated Hepatocellular Carcinoma by Gyöngyösi, Benedek, Végh, Éva, Járay, Balázs, Székely, Eszter, Fassan, Matteo, Bodoky, György, Schaff, Zsuzsa, Kiss, András

“…Sorafenib represents the first effective targeted therapy for advanced stage hepatocellular carcinoma (HCC); however, adequate patient stratification regarding…”
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Claudin 1 Expression Characterizes Human Uterine Cervical Reserve Cells by Zinner, Balázs, Gyöngyösi, Benedek, Babarczi, Edit, Kiss, András, Sobel, Gábor

“…Stem cells participate in cervical carcinogenesis but their function and exact features are still not clear. One type of stem-like cells are endocervical…”
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Hepatocellular carcinoma is accelerated by NASH involving M2 macrophage polarization mediated by hif-1αinduced IL-10 by Ambade, Aditya, Satishchandran, Abhishek, Saha, Banishree, Gyongyosi, Benedek, Lowe, Patrick, Kodys, Karen, Catalano, Donna, Szabo, Gyongyi

“…Obesity-related inflammation promotes cancer development. Tissue resident macrophages affect tumor progression and the tumor micro-environment favors…”
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Distinct Claudin Expression Profiles of Hepatocellular Carcinoma and Metastatic Colorectal and Pancreatic Carcinomas by Holczbauer, Ágnes, Gyöngyösi, Benedek, Lotz, Gábor, Szijártó, Attila, Kupcsulik, Péter, Schaff, Zsuzsa, Kiss, András

“…Tight junction proteins, including claudins, are often dysregulated during carcinogenesis and tumor progression. Moreover, the claudin expression pattern…”
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Inhibition of spleen tyrosine kinase activation ameliorates inflammation, cell death, and steatosis in alcoholic liver disease by Bukong, Terence N., Iracheta‐Vellve, Arvin, Saha, Banishree, Ambade, Aditya, Satishchandran, Abhishek, Gyongyosi, Benedek, Lowe, Patrick, Catalano, Donna, Kodys, Karen, Szabo, Gyongyi

“…The spectrum of alcoholic liver disease (ALD) is a major cause of mortality with limited therapies available. Because alcohol targets numerous signaling…”
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Paraneoplastic Kelch-like protein 11 antibody-associated cerebellar and limbic encephalitis caused by metastatic “burned-out” seminoma – A scar(r)y phenomenon by Gyongyosi, Benedek, Magyar-Stang, Rita, Takacs, Timea, Szekely, Eszter, Illes, Zsolt, Nilsson, Christine, Gyorke, Tamas, Barsi, Peter, Juhasz, Daniel, Banky, Balazs, Bereczki, Daniel, Honnorat, Jerome, Gunda, Bence

“…The diagnosis of paraneoplastic neurologic syndromes is challenging when the primary tumor masquerades as scar tissue (i.e. “burned-out”). Case report. A…”
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