Search Results - "Gylfe, Åsa"

Inhibitory activity of the isoflavone biochanin A on intracellular bacteria of genus Chlamydia and initial development of a buccal formulation by Hanski, Leena, Genina, Natalja, Uvell, Hanna, Malinovskaja, Kristina, Gylfe, Åsa, Laaksonen, Timo, Kolakovic, Ruzica, Mäkilä, Ermei, Salonen, Jarno, Hirvonen, Jouni, Elofsson, Mikael, Sandler, Niklas, Vuorela, Pia M

“…Given the established role of Chlamydia spp. as causative agents of both acute and chronic diseases, search for new antimicrobial agents against these…”
Get full text

Metabolites in Blood for Prediction of Bacteremic Sepsis in the Emergency Room by Kauppi, Anna M, Edin, Alicia, Ziegler, Ingrid, Mölling, Paula, Sjöstedt, Anders, Gylfe, Åsa, Strålin, Kristoffer, Johansson, Anders

“…A metabolomics approach for prediction of bacteremic sepsis in patients in the emergency room (ER) was investigated. In a prospective study, whole blood…”
Get full text

A Small-Molecule Inhibitor of Type III Secretion Inhibits Different Stages of the Infectious Cycle of Chlamydia trachomatis by Muschiol, Sandra, Bailey, Leslie, Gylfe, Åsa, Sundin, Charlotta, Hultenby, Kjell, Bergström, Sven, Elofsson, Mikael, Wolf-Watz, Hans, Normark, Staffan, Henriques-Normark, Birgitta

“…The intracellular pathogen Chlamydia trachomatis possesses a type III secretion (TTS) system believed to deliver a series of effector proteins into the…”
Get full text

Mutations in hemG Mediate Resistance to Salicylidene Acylhydrazides, Demonstrating a Novel Link between Protoporphyrinogen Oxidase (HemG) and Chlamydia trachomatis Infectivity by Engström, Patrik, Nguyen, Bidong D, Normark, Johan, Nilsson, Ingela, Bastidas, Robert J, Gylfe, Asa, Elofsson, Mikael, Fields, Kenneth A, Valdivia, Raphael H, Wolf-Watz, Hans, Bergström, Sven

“…OA  Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

Osteoprotegerin Promotes Fibrous Cap Formation in Atherosclerotic Lesions of ApoE-Deficient Mice—Brief Report by Ovchinnikova, Olga, Gylfe, Åsa, Bailey, Leslie, Nordström, Anna, Rudling, Mats, Jung, Christian, Bergström, Sven, Waldenström, Anders, Hansson, Göran K, Nordström, Peter

“…OBJECTIVE—Osteoprotegerin (OPG) is a tumor necrosis factor receptor–related cytokine, initially found to inhibit osteoclastogenesis. In the present study we…”
Get full text

Small molecule inhibitors of type III secretion in Yersinia block the Chlamydia pneumoniae infection cycle by Bailey, Leslie, Gylfe, Åsa, Sundin, Charlotta, Muschiol, Sandra, Elofsson, Mikael, Nordström, Peter, Henriques-Normark, Birgitta, Lugert, Raimond, Waldenström, Anders, Wolf-Watz, Hans, Bergström, Sven

“…Intracellular parasitism by Chlamydiales is a complex process involving transmission of metabolically inactive particles that differentiate, replicate, and…”
Get full text

Introduction of a Comprehensive Diagnostic and Interdisciplinary Management Approach in Haematological Patients with Mucormycosis: A Pre and Post-Intervention Analysis by Risum, Malene, Helweg-Larsen, Jannik, Petersen, Søren Lykke, Kampmann, Peter, Overgaard, Ulrik Malthe, El Fassi, Daniel, Nielsen, Ove Juul, Brabrand, Mette, Rubek, Niclas, Munksgaard, Lars, Severinsen, Marianne Tang, Nielsen, Bendt, Gertsen, Jan Berg, Gylfe, Åsa, Hjort, Ulla, Vourtsi, Angeliki, Hare, Rasmus Krøger, Arendrup, Maiken Cavling

“…Mucormycosis is a life threatening infection in patients with haematological disease. We introduced a Mucorales-PCR and an aggressive, multidisciplinary…”
Get full text

Antibiotics Use and Subsequent Risk of Colorectal Cancer: A Swedish Nationwide Population-Based Study by Lu, Sai San Moon, Mohammed, Zahraa, Häggström, Christel, Myte, Robin, Lindquist, Elisabeth, Gylfe, Åsa, Van Guelpen, Bethany, Harlid, Sophia

“…Abstract Background Antibiotics use may increase colorectal cancer (CRC) risk by altering the gut microbiota, with suggestive evidence reported. Our study aims…”
Get full text

Natural product inspired library synthesis - Identification of 2,3-diarylbenzofuran and 2,3-dihydrobenzofuran based inhibitors of Chlamydia trachomatis by Saleeb, Michael, Mojica, Sergio, Eriksson, Anna U., Andersson, C. David, Gylfe, Åsa, Elofsson, Mikael

“…A natural product inspired library was synthesized based on 2,3-diarylbenzofuran and 2,3-diaryl-2,3-dihydrobenzofuran scaffolds. The library of forty-eight…”
Get full text

Prediagnostic Prescription Antibiotics Use and Survival in Patients with Colorectal Cancer: A Swedish National Register-Based Study by Lu, Sai San Moon, Rutegård, Martin, Ahmed, Maghfoor, Häggström, Christel, Gylfe, Åsa, Harlid, Sophia, Van Guelpen, Bethany

“…Abstract Background: Antibiotics use is associated with higher colorectal cancer risk, but little is known regarding any potential effects on survival…”
Get full text

Design, synthesis and evaluation of novel polypharmacological antichlamydial agents by Sunduru, Naresh, Salin, Olli, Gylfe, Åsa, Elofsson, Mikael

“…Discovery of new polypharmacological antibacterial agents with multiple modes of actions can be an alternative to combination therapy and also a possibility to…”
Get full text

Phospholipid levels in blood during community-acquired pneumonia by Müller, Daniel C, Kauppi, Anna, Edin, Alicia, Gylfe, Åsa, Sjöstedt, Anders B, Johansson, Anders

“…Phospholipids, major constituents of bilayer cell membranes, are present in large amounts in pulmonary surfactant and play key roles in cell signaling. Here,…”
Get full text

Mosquitoborne Sindbis Virus Infection and Long-Term Illness by Gylfe, Åsa, Ribers, Åsa, Forsman, Oscar, Bucht, Göran, Alenius, Gerd-Marie, Wållberg-Jonsson, Solveig, Ahlm, Clas, Evander, Magnus

“…An unexpected human outbreak of the mosquitoborne Sindbis virus occurred in a previously nonendemic area of Sweden. At follow-up, 6-8 months after infection,…”
Get full text

A 2-pyridone amide inhibitor of transcriptional activity in Chlamydia trachomatis by Núñez-Otero, Carlos, Bahnan, Wael, Vielfort, Katarina, Silver, Jim, Singh, Pardeep, Elbir, Haitham, Almqvist, Fredrik, Bergström, Sven, Gylfe, Åsa

“…is a strict intracellular bacterium that causes sexually transmitted infections and eye infections that can lead to life-long sequelae. Treatment options are…”
Get full text

Modified Fluoroquinolones as Antimicrobial Compounds Targeting Chlamydia trachomatis by Vu, Thi Huyen, Adhel, Erika, Vielfort, Katarina, Ha Duong, Ngûyet-Thanh, Anquetin, Guillaume, Jeannot, Katy, Verbeke, Philippe, Hjalmar, Sofia, Gylfe, Åsa, Serradji, Nawal

“…Chlamydia trachomatis causes the most common sexually transmitted bacterial infection and trachoma, an eye infection. Untreated infections can lead to…”
Get full text

High prevalence of pharyngeal bacterial pathogens among healthy adolescents and young adults by Agerhäll, Martin, Henrikson, Martin, Johansson Söderberg, Jenny, Sellin, Mats, Tano, Krister, Gylfe, Åsa, Berggren, Diana

“…The pharyngeal mucosa can be colonized with bacteria that have potential to cause pharyngotonsillitis. By the use of culturing techniques and PCR, we aimed to…”
Get full text

Thiazolino 2‑Pyridone Amide Inhibitors of Chlamydia trachomatis Infectivity by Good, James A. D, Silver, Jim, Núñez-Otero, Carlos, Bahnan, Wael, Krishnan, K. Syam, Salin, Olli, Engström, Patrik, Svensson, Richard, Artursson, Per, Gylfe, Åsa, Bergström, Sven, Almqvist, Fredrik

“…The bacterial pathogen Chlamydia trachomatis is a global health burden currently treated with broad-spectrum antibiotics which disrupt commensal bacteria. We…”
Get full text

Thiazolino 2‑Pyridone Amide Isosteres As Inhibitors of Chlamydia trachomatis Infectivity by Good, James A. D, Kulén, Martina, Silver, Jim, Krishnan, K. Syam, Bahnan, Wael, Núñez-Otero, Carlos, Nilsson, Ingela, Wede, Emma, de Groot, Esmee, Gylfe, Åsa, Bergström, Sven, Almqvist, Fredrik

“…Chlamydia trachomatis is a global health burden due to its prevalence as a sexually transmitted disease and as the causative agent of the eye infection…”
Get full text

Changes in testing and incidence of Chlamydia trachomatis and Neisseria gonorrhoeae - the possible impact of the COVID-19 pandemic in the three Scandinavian countries by Ivarsson, Lovisa, de Arriba Sánchez de la Campa, Magdalena, Elfving, Karin, Yin, Hong, Gullsby, Karolina, Stark, Lisa, Andersen, Berit, Hoffmann, Steen, Gylfe, Åsa, Unemo, Magnus, Herrmann, Björn

“…This study aimed to investigate what impact the COVID-19 pandemic and its associated restrictions had on Chlamydia trachomatis and Neisseria gonorrhoeae…”
Get full text

Statistical molecular design of a focused salicylidene acylhydrazide library and multivariate QSAR of inhibition of type III secretion in the Gram-negative bacterium Yersinia by Dahlgren, Markus K., Zetterström, Caroline E., Gylfe, Åsa, Linusson, Anna, Elofsson, Mikael

“…A combined application of statistical molecular design (SMD), quantitative structure–activity relationship (QSAR) modeling and prediction of new active…”
Get full text