Search Results - "Gyetko, Margaret R"

Activation of Urokinase Plasminogen Activator and Its Receptor Axis Is Essential for Macrophage Infiltration in a Prostate Cancer Mouse Model by Zhang, Jian, Sud, Sudha, Mizutani, Kosuke, Gyetko, Margaret R, Pienta, Kenneth J

“…Abstract Macrophages within the tumor microenvironment promote angiogenesis, extracellular matrix breakdown, and tumor cell migration, invasion, and…”
Get full text

Predictors of job satisfaction among academic faculty members: do instructional and clinical staff differ? by Chung, Kevin C, Song, Jae W, Kim, H Myra, Woolliscroft, James O, Quint, Elisabeth H, Lukacs, Nicholas W, Gyetko, Margaret R

“…Medical Education 2010: 44>: 985–995 Objectives  This study aimed to identify and compare predictors of job satisfaction between instructional and clinical…”
Get full text

Hepatocyte growth factor acts as a mitogen and chemoattractant for postnatal subventricular zone-olfactory bulb neurogenesis by Wang, Tsu-Wei, Zhang, Huailin, Gyetko, Margaret R., Parent, Jack M.

“…Neural progenitor cells persist throughout life in the forebrain subventricular zone (SVZ). They generate neuroblasts that migrate to the olfactory bulb and…”
Get full text

Urokinase-Type Plasminogen Activator Potentiates Lipopolysaccharide-Induced Neutrophil Activation by Abraham, Edward, Gyetko, Margaret R, Kuhn, Katherine, Arcaroli, John, Strassheim, Derek, Park, Jong Sung, Shetty, Sreerama, Idell, Steven

“…Urokinase plasminogen activator (uPA) is a serine protease that catalyzes the conversion of plasminogen to plasmin. Although increased circulating levels of…”
Get full text

Urokinase-deficient and urokinase receptor-deficient mice have impaired neutrophil antimicrobial activation in vitro by Gyetko, M R, Aizenberg, D, Mayo-Bond, L

“…Leukocytes express both urokinase‐type plasminogen activator (uPA) and the urokinase receptor (uPAR, CD87). We have shown that neutrophil recruitment to the…”
Get full text

Gender Disparities in Academic Practice by Waljee, Jennifer F., Chang, Kate Wan-Chu, Kim, H. Myra, Gyetko, Margaret R., Quint, Elisabeth H., Lukacs, Nicholas W., Woolliscroft, James O., Chung, Kevin C.

“…In academia, women remain underrepresented. The authors' sought to examine differences in faculty position and professional satisfaction among academic…”
Get full text

Induction of p53 by Urokinase in Lung Epithelial Cells by Shetty, Sreerama, Gyetko, Margaret R., Mazar, Andrew P.

“…Urokinase plasminogen activator (uPA) is a serine protease that catalyzes the conversion of plasminogen to plasmin. The plasminogen/plasmin system includes the…”
Get full text

Urokinase-Deficient Mice Fail To Generate a Type 2 Immune Response following Schistosomal Antigen Challenge by GYETKO, Margaret R, SUD, Sudha, CHENSUE, Stephen W

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
Get full text

Regulation of alveolar epithelial cell apoptosis and pulmonary fibrosis by coordinate expression of components of the fibrinolytic system by Bhandary, Yashodhar P, Shetty, Shwetha K, Marudamuthu, Amarnath S, Gyetko, Margaret R, Idell, Steven, Gharaee-Kermani, Mehrnaz, Shetty, Rashmi S, Starcher, Barry C, Shetty, Sreerama

“…Alveolar type II (ATII) cell apoptosis and depressed fibrinolysis that promotes alveolar fibrin deposition are associated with acute lung injury (ALI) and the…”
Get more information

New insights into the pathogenesis and treatment of idiopathic pulmonary fibrosis : A potential role for stem cells in the lung parenchyma and implications for therapy by GHARAEE-KERMANI, Mehrnaz, GYETKO, Margaret R, BIAO HU, PHAN, Sem H

“…Idiopathic Pulmonary Fibrosis (IPF) is a chronic, progressive, and often fatal form of interstitial lung disease. It is characterized by injury with loss of…”
Get full text

Mactinin treatment promotes wound-healing-associated inflammation in urokinase knockout mice by Luikart, Sharon D., Levay-Young, Brett, Hinkel, Tim, Shearer, Jeffry, Mills, Charles, Caldwell, Michael D., Gyetko, Margaret R., Oegema, Theodore R.

“…ABSTRACT Mactinin, a 31 kDa fragment from the amino‐terminal end of α‐actinin, is chemotactic for monocytes and can promote monocyte/macrophage maturation…”
Get full text

Matrix Metalloproteinases Regulate Neovascularization by Acting as Pericellular Fibrinolysins by Hiraoka, Nobuaki, Allen, Edward, Apel, Ingrid J, Gyetko, Margaret R, Weiss, Stephen J

“…During angiogenesis, endothelial cells penetrate fibrin barriers via undefined proteolytic mechanisms. We demonstrate that the fibrinolytic plasminogen…”
Get full text

Symptom-related sputum microbiota in stable chronic obstructive pulmonary disease by Diao, Wenqi, Shen, Ning, Du, Yipeng, Erb-Downward, John R, Sun, Xiaoyan, Guo, Chenxia, Ke, Qian, Huffnagle, Gary B, Gyetko, Margaret R, He, Bei

“…The role of airway microbiota in COPD is highly debated. Symptomology assessment is vital for the management of clinically stable COPD patients; however, the…”
Get full text

Urokinase Receptor-Deficient Mice Have Impaired Neutrophil Recruitment in Response to Pulmonary Pseudomonas aeruginosa Infection by Gyetko, Margaret R, Sud, Sudha, Kendall, Tara, Fuller, Jennifer A, Newstead, Michael W, Standiford, Theodore J

“…Leukocytes express both urokinase-type plasminogen activator (uPA) and the urokinase receptor (uPAR, CD87). Evidence in vitro has implicated uPAR as a…”
Get full text

Induction of Tissue Factor by Urokinase in Lung Epithelial Cells and in the Lungs by SHETTY, Sreerama, BHANDARY, Yashodhar P, RUPPERT, Clemens, GUENTHER, Andreas, ABRAHAM, Edward, SHETTY, Rashmi S, SHITTY, Shwetha K, VELUSAMY, Thirunavukkarasu, SHETTY, Praveenkumar, BDEIR, Khalil, GYETKO, Margaret R, CINES, Douglas B, IDELL, Steven, NEUENSCHWANDER, Pierre F

“…Urokinase-type plasminogen activator (uPA) regulates extracellular proteolysis in lung injury and repair. Although alveolar expression of uPA increases,…”
Get full text

The role of urokinase in idiopathic pulmonary fibrosis and implication for therapy by Gharaee-Kermani, Mehrnaz, Hu, Biao, Phan, Sem H, Gyetko, Margaret R

“…Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive and frequently fatal form of interstitial lung disease for which there are no proven drug…”
Get more information

Use of Direct Gradient Analysis to Uncover Biological Hypotheses in 16S Survey Data and Beyond by Erb-Downward, John R., Sadighi Akha, Amir A., Wang, Juan, Shen, Ning, He, Bei, Martinez, Fernando J., Gyetko, Margaret R., Curtis, Jeffrey L., Huffnagle, Gary B.

“…This study investigated the use of direct gradient analysis of bacterial 16S pyrosequencing surveys to identify relevant bacterial community signals in the…”
Get full text

Current and emerging drugs for idiopathic pulmonary fibrosis by Gharaee-Kermani, Mehrnaz, Hu, Biao, Thannickal, Victor J, Phan, Sem H, Gyetko, Margaret R

“…Idiopathic pulmonary fibrosis is a chronic, progressive and often fatal form of interstitial lung disease. It is characterized by injury with loss of lung…”
Get more information

Urokinase-Type Plasminogen Activator Is Required for the Generation of a Type 1 Immune Response to Pulmonary Cryptococcus neoformans Infection by Gyetko, Margaret R, Sud, Sudha, Chen, Gwo-Hsiao, Fuller, Jennifer A, Chensue, Stephen W, Toews, Galen B

“…Urokinase-type plasminogen activator (uPA)(-/-) mice cannot mount protective host defenses during infection with the opportunistic yeast Cryptococcus…”
Get full text

Cutting Edge: Antigen-Driven Lymphocyte Recruitment to the Lung Is Diminished in the Absence of Urokinase-Type Plasminogen Activator (uPA) Receptor, but Is Independent of uPA by Gyetko, Margaret R, Sud, Sudha, Sonstein, Joanne, Polak, Timothy, Sud, Anchal, Curtis, Jeffrey L

“…Abstract The requirement for urokinase plasminogen activator (uPA) and uPA receptor (uPAR) in T lymphocyte migration is unknown. uPA−/− mice have fewer…”
Get full text