Search Results - "Gyemant, Nora"

Reversal of Multidrug Resistance of Cancer Cells In Vitro: Modification of Drug Resistance by Selected Carotenoids by GYEMANT, Nora, TANAKA, Masaru, MOLNAR, Péter, DELI, Jozsef, MANDOKY, Laszlo, MOLNAR, Joseph

“…The development of multidrug resistance (MDR) causes difficulties in the chemotherapy of of human cancer. Investigation of the possibility of reversal of MDR…”
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Euphoportlandols A and B, Tetracylic Diterpene Polyesters from Euphorbia portlandica and Their Anti-MDR Effects in Cancer Cells by Madureira, A.M, Gyémánt, N, Ascenso, J.R, Abreu, P.M, Molnár, J, Ferreira, M.J.U

“…Two new tetracyclic diterpene polyesters, euphoportlandols A (1) and B (2), have been isolated along with 12 known tetracyclic triterpenes from an acetone…”
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New macrocyclic lathyrane diterpenes, from Euphorbia lagascae, as inhibitors of multidrug resistance of tumour cells by Duarte, Noélia, Gyémánt, Nora, Abreu, Pedro M, Molnár, Joseph, Ferreira, Maria-José U

“…The new macrocyclic lathyrane diterpenes latilagascenes A and B ( 1 and 2), the diacetylated derivative of 2, latilagascene C ( 3), and the known diterpenes…”
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Interaction between Doxorubicin and the Resistance Modifier Stilbene on Multidrug Resistant Mouse Lymphoma and Human Breast Cancer Cells by FERREIRA, Maria-José U, DUARTE, Noélia, GYEMANT, Nora, RADICS, Rita, CHEREPNEV, Georgy, VARGA, Andras, MOLNAR, Joseph

“…The hydroxystilbene trans-3,5,3′,4′-tetrahydroxystilbene (piceatannol) (1) , isolated from the methanol extract of Euphorbia lagascae defatted seeds, was…”
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The Effects of Jatrophane Derivatives on the Reversion of MDR1- and MRP-mediated Multidrug Resistance in the MDA-MB-231 (HTB-26) Cell Line by FERREIRA, Maria-José U, GYEMANT, Nora, MADUREIRA, Ana Margarida, TANAKA, Masaru, KOOS, Kitti, DIDZIAPETRIS, Remigijus, MOLNAR, Joseph

“…Multidrug resistance (MDR) of cancer cells can be the result of a variety of mechanisms that are not completely understood. One of the most significant among…”
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Pubescenes, jatrophane diterpenes, from Euphorbia pubescens, with multidrug resistance reversing activity on mouse lymphoma cells by Valente, Cláudia, Ferreira, Maria José, Abreu, Pedro M, Gyémánt, Nora, Ugocsai, Katalin, Hohmann, Judit, Molnár, Joseph

“…The macrocyclic jatrophane diterpene polyesters, pubescenes A - D ( 1 - 4) were isolated from the whole dried plant of Euphorbia pubescens, and evaluated for…”
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Inhibition of P-glycoprotein Transport Activity in a Resistant Mouse Lymphoma Cell Line by Diterpenic Lactones by FERREIRA, Maria-José U, GYEMANT, Nora, MADUREIRA, Ana M, MOLNAR, Joseph

“…Multidrug resistance (MDR) is believed to be a major reason for the failure of cancer treatment. It is in most cases caused by the activity of the various ABC…”
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Rearranged jatrophane-type diterpenes from euphorbia species. Evaluation of their effects on the reversal of multidrug resistance by Madureira, Ana M, Ferreira, Maria-José U, Gyémánt, Nora, Ugocsai, Katalin, Ascenso, José R, Abreu, Pedro M, Hohmann, Judit, Molnár, Joseph

“…The rearranged jatrophane-type diterpenes ( 1 - 3), isolated from the Me (2)CO extracts of Euphorbia portlandica and Euphorbia segetalis, were examined for…”
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Metabolic syndrome influences cardiac gene expression pattern at the transcript level in male ZDF rats by Sárközy, Márta, Zvara, Agnes, Gyémánt, Nóra, Fekete, Veronika, Kocsis, Gabriella F, Pipis, Judit, Szűcs, Gergő, Csonka, Csaba, Puskás, László G, Ferdinandy, Péter, Csont, Tamás

“…Metabolic syndrome (coexisting visceral obesity, dyslipidemia, hyperglycemia, and hypertension) is a prominent risk factor for cardiovascular morbidity and…”
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Carotenoids with anti-Helicobacter pylori activity from Golden delicious apple by Molnár, Péter, Deli, József, Tanaka, Toru, Kann, Yoshiyuki, Tani, Satoru, Gyémánt, Nóra, Molnár, Joseph, Kawase, Masami

“…Previously it was reported that hypophasic carotenoids of Golden delicious apple peel showed potent anti-H. pylori activity (MIC₅₀ = 36 μg/mL), comparable to…”
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New Potent P-Glycoprotein Inhibitors Carrying a Polycyclic Scaffold by Bisi, Alessandra, Gobbi, Silvia, Rampa, Angela, Belluti, Federica, Piazzi, Lorna, Valenti, Piero, Gyemant, Nora, Molnár, Joseph

“…New pentacyclic inhibitors of the P-glycoprotein carrying nitrogen-containing alkyl chains were synthesized and evaluated for MDR reverting activity on mouse…”
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Inhibition of multidrug resistance of cancer cells by natural diterpenes, triterpenes and carotenoids by Molnár, Joseph, Gyémánt, Nóra, Tanaka, Masaru, Hohmann, Judith, Bergmann-Leitner, Elke, Molnár, Péter, Deli, Joseph, Didiziapetris, Remigijus, Ferreira, Maria José Umbelino

“…The multidrug resistance (MDR) proteins are member of the ATP-binding cassette superfamily and are present in a majority of human tumors. Their activity is a…”
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Carotenoid composition and in vitro pharmacological activity of rose hips by Horváth, Györgyi, Molnár, Péter, Radó-Turcsi, Erika, Deli, József, Kawase, Masami, Satoh, Kazue, Tanaka, Toru, Tani, Satoru, Sakagami, Hiroshi, Gyémánt, Nóra, Molnár, József

“…The aim of the present study was to compare carotenoid extracts of Rose hips (Rosa canina L.) with regard to their phytochemical profiles and their in vitro…”
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Biological activity of carotenoids in red paprika, Valencia orange and Golden delicious apple by Molnar, P, Kawase, M, Satoh, K, Sohara, Y, Tanaka, T, Tani, S, Sakagami, H, Nakashima, H, Motohashi, N, Gyemant, N

“…Carotenoid fractions were extracted from red paprika, Valencia orange peel and the peel of Golden delicious apple. Thus, hypophasic carotenoids of paprika…”
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Biological activity of Barbados cherry (Acerola fruits, fruit of Malpighia emarginata DC) extracts and fractions by Motohashi, N, Wakabayashi, H, Kurihara, T, Fukushima, H, Yamada, T, Kawase, M, Sohara, Y, Tani, S, Shirataki, Y, Sakagami, H

“…Fractionation of barbados cherry (acerola fruit, a fruit of Malpighia emarginata DC.) extracts were performed by organic solvent extractions and column…”
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Modelling of tumour--host coexistence In vitro in the presence of serine protease inhibitors by Engi, Helga, Gyémánt, Nóra, Ohkoshi, Motohiro, Amaral, Leonard, Molnár, Joseph

“…The activities of cell surface serine proteases are markedly enhanced in malignant tumours. Proteolytic degradation of the extracellular matrix and basal…”
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Interaction of tomato lectin with ABC transporter in cancer cells: Glycosylation confers functional conformation of P-gp by Molnár, Joseph, Kars, Meltem Demirel, Gündüz, Ufuk, Engi, Helga, Schumacher, Udo, Van Damme, Els J., Peumans, Willy J., Makovitzky, Josef, Gyémánt, Nóra, Molnár, Péter

“…Phospho-glycoprotein (P-gp) is a polytopic plasma membrane protein whose overexpression causes multidrug resistance (MDR) responsible for the failure of cancer…”
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Comparative effects on intestinal absorption in situ by P-glycoprotein-modifying HIV protease inhibitors by Richter, Martin, Gyémánt, Nóra, Molnár, Joséf, Hilgeroth, Andreas

“…P-glycoprotein (P-gp) is made responsible for the limited oral bioavailability of P-gp substrates like peptidic HIV protease inhibitors (PIs). With respect to…”
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P-Glycoprotein Effects of Cyclic Urea HIV Protease Inhibitor DMP 323 in Competitional Absorption Studies by Richter, Martin, Gyémánt, Nóra, Molnár, Joséf, Hilgeroth, Andreas

“…Cyclic ureas form a perspective class of non‐peptidic HIV‐1 protease inhibitors with major bioavailability problems. Low absorption rates of DMP 323 as one of…”
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Euphoportlandols A and B, Tetracylic Diterpene Polyesters from Euphorbia p ortlandica and Their Anti-MDR Effects in Cancer Cells by Madureira, Ana M, Gyémánt, Nora, Ascenso, José R, Abreu, Pedro M, Molnár, Joseph, Ferreira, Maria-José U

“…Two new tetracyclic diterpene polyesters, euphoportlandols A (1) and B (2), have been isolated along with 12 known tetracyclic triterpenes from an acetone…”
Get full text