Search Results - "Gwon Park, Chun"
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Reduced restenosis and enhanced re-endothelialization of functional biodegradable vascular scaffolds by everolimus and magnesium hydroxide
Published in Biomaterials research (21-12-2022)“…Coronary artery disease is a cardiovascular disease with a high mortality and mortality rate in modern society. Vascular stent insertion to restore blood flow…”
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2
Protein-Based Nanoparticles as Drug Delivery Systems
Published in Pharmaceutics (29-06-2020)“…Nanoparticles have been extensively used as carriers for the delivery of chemicals and biomolecular drugs, such as anticancer drugs and therapeutic proteins…”
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3
T cell-targeting nanoparticles focus delivery of immunotherapy to improve antitumor immunity
Published in Nature communications (23-11-2017)“…Targeted delivery of compounds to particular cell subsets can enhance therapeutic index by concentrating their action on the cells of interest. Because…”
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4
Neutrophil extracellular traps produced during inflammation awaken dormant cancer cells in mice
Published in Science (American Association for the Advancement of Science) (28-09-2018)“…Cancer cells from a primary tumor can disseminate to other tissues, remaining dormant and clinically undetectable for many years. Little is known about the…”
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5
T‐Cell‐Derived Nanovesicles for Cancer Immunotherapy
Published in Advanced materials (Weinheim) (01-08-2021)“…Although T‐cell therapy is a remarkable breakthrough in cancer immunotherapy, the therapeutic efficacy is limited for solid tumors. A major cause of the low…”
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Combination of Metal‐Phenolic Network‐Based Immunoactive Nanoparticles and Bipolar Irreversible Electroporation for Effective Cancer Immunotherapy
Published in Small (Weinheim an der Bergstrasse, Germany) (01-06-2022)“…To circumvent the limitations of conventional cancer immunotherapy, it is critical to prime antigen‐presenting cells (APCs) to initiate the cancer‐immune…”
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Metal-organic frameworks, NH2-MIL-88(Fe), as carriers for ophthalmic delivery of brimonidine
Published in Acta biomaterialia (01-10-2018)“…[Display omitted] We have proposed a metal-organic framework (MOF), NH2-MIL-88(Fe), as a novel carrier for topical drug delivery to the eye. The NH2-MIL-88(Fe)…”
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FRACTAL: Signal amplification of immunofluorescence via cyclic staining of target molecules
Published in Nanoscale (08-12-2020)“…In this article, we demonstrate fluorescent signal amplification via cyclic staining of target molecules (FRACTAL), a technique that can amplify the signal…”
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Enhancing CAR‐NK Cells Against Solid Tumors Through Chemical and Genetic Fortification with DOTAP‐Functionalized Lipid Nanoparticles
Published in Advanced functional materials (01-07-2024)“…Natural killer (NK) cells are crucial in the innate immune response and show promise in cancer immunotherapy, but face challenges in activation and targeted…”
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10
Thermosensitive hexanoyl glycol chitosan-based ocular delivery system for glaucoma therapy
Published in Acta biomaterialia (15-07-2016)“…[Display omitted] Conventional eye drops quickly move away from the surface of the eye; as a result, ocular bioavailability is very limited. To overcome this…”
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11
Immune cell targeting nanoparticles: a review
Published in Biomaterials research (20-12-2021)“…Immune cells are attractive targets for therapy as they are direct participants in a variety of diseases. Delivering a therapeutic agent only to cells that act…”
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12
The Upregulation of Regenerative Activity for Extracellular Vesicles with Melatonin Modulation in Chemically Defined Media
Published in International journal of molecular sciences (01-12-2022)“…Extracellular vesicles (EVs) derived from human mesenchymal stem cells (hMSCs) have been widely known to have therapeutic effects by representing…”
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13
An electro-ferroptotic nanoammunition enables image-guided, spatiotemporally controlled cancer ferroptosis induction via irreversible electroporation
Published in Chemical engineering journal (Lausanne, Switzerland : 1996) (01-05-2024)“…An IRE-triggered electro-ferroptotic nanoammunition (EFN) has been developed, which enables controlled release of Fe2+ ions for effective cancer treatment. The…”
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A Spheroid‐Forming Hybrid Gold Nanostructure Platform That Electrochemically Detects Anticancer Effects of Curcumin in a Multicellular Brain Cancer Model
Published in Small (Weinheim an der Bergstrasse, Germany) (01-04-2021)“…In this study, a multifunctional platform that enables the highly efficient formation of 3D multicellular cancer spheroids and precise real‐time assessments of…”
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15
Implantable small device enabled with magnetic actuation for on-demand and pulsatile drug delivery
Published in Journal of controlled release (28-09-2018)“…We prepared an implantable device of small volume (SID) that is enabled with on-demand, pulsatile drug release. The device was designed to be actuated via a…”
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Combination of Metal‐Phenolic Network‐Based Immunoactive Nanoparticles and Bipolar Irreversible Electroporation for Effective Cancer Immunotherapy (Small 25/2022)
Published in Small (Weinheim an der Bergstrasse, Germany) (01-06-2022)“…Cancer Immunotherapy In article number 2200316, Dong Keun Han, Ik‐Hwan Kim, Wooram Park, and co‐workers present a combination therapy of metal‐phenolic…”
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17
Implantable batteryless device for on-demand and pulsatile insulin administration
Published in Nature communications (13-04-2017)“…Many implantable systems have been designed for long-term, pulsatile delivery of insulin, but the lifetime of these devices is limited by the need for battery…”
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Biofunctional Layered Double Hydroxide Nanohybrids for Cancer Therapy
Published in Materials (01-11-2022)“…Layered double hydroxides (LDHs) with two-dimensional nanostructure are inorganic materials that have attractive advantages such as biocompatibility, facile…”
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Defined MSC exosome with high yield and purity to improve regenerative activity
Published in Journal of tissue engineering (2021)“…Exosomes derived from mesenchymal stem cells (MSCs) have been studied as vital components of regenerative medicine. Typically, various isolation methods of…”
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Mucoadhesive and antifouling Janus polysaccharide film for prevention of colorectal cancer recurrence post‐surgery
Published in BMEmat (Print) (01-06-2024)“…Colorectal cancer is one of the most common cancers, and current treatment options include surgery, chemotherapy, and radiation therapy. Most patients undergo…”
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