Search Results - "Gwendolen, Reilly"

Intrinsic extracellular matrix properties regulate stem cell differentiation by Reilly, Gwendolen C, Engler, Adam J

“…Abstract One of the recent paradigm shifts in stem cell biology has been the discovery that stem cells can begin to differentiate into mature tissue cells when…”
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In vitro Models of Bone Remodelling and Associated Disorders by Owen, Robert, Reilly, Gwendolen C

“…Disruption of bone remodelling by diseases such as osteoporosis results in an imbalance between bone formation by osteoblasts and resorption by osteoclasts…”
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Boosting the Osteogenic and Angiogenic Performance of Multiscale Porous Polycaprolactone Scaffolds by In Vitro Generated Extracellular Matrix Decoration by Aldemir Dikici, Betül, Reilly, Gwendolen C, Claeyssens, Frederik

“…Tissue engineering (TE)-based bone grafts are favorable alternatives to autografts and allografts. Both biochemical properties and the architectural features…”
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3D surface topology guides stem cell adhesion and differentiation by Viswanathan, Priyalakshmi, Ondeck, Matthew G, Chirasatitsin, Somyot, Ngamkham, Kamolchanok, Reilly, Gwendolen C, Engler, Adam J, Battaglia, Giuseppe

“…Abstract Polymerized high internal phase emulsion (polyHIPE) foams are extremely versatile materials for investigating cell–substrate interactions in vitro …”
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Emulsion templated scaffolds manufactured from photocurable polycaprolactone by Aldemir Dikici, Betül, Sherborne, Colin, Reilly, Gwendolen C., Claeyssens, Frederik

“…Emulsion templating is an emerging route for the production of highly porous scaffolds (PolyHIPEs) with interconnected porosity. Polycaprolactone (PCL) is one…”
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A Novel Bilayer Polycaprolactone Membrane for Guided Bone Regeneration: Combining Electrospinning and Emulsion Templating by Aldemir Dikici, Betül, Dikici, Serkan, Reilly, Gwendolen C, MacNeil, Sheila, Claeyssens, Frederik

“…Guided bone regeneration is a common dental implant treatment where a barrier membrane (BM) is used between epithelial tissue and bone or bone graft to prevent…”
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Selective laser melting processed Ti6Al4V lattices with graded porosities for dental applications by Wally, Zena J, Haque, Abdul M, Feteira, Antonio, Claeyssens, Frederik, Goodall, Russell, Reilly, Gwendolen C

“…Dental implants need to support good osseointegration into the surrounding bone for full functionality. Interconnected porous structures have a lower stiffness…”
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Preparation of Interconnected Pickering Polymerized High Internal Phase Emulsions by Arrested Coalescence by Durgut, Enes, Sherborne, Colin, Aldemir Dikici, Betül, Reilly, Gwendolen C., Claeyssens, Frederik

“…Emulsion templating is a method that enables the production of highly porous and interconnected polymer foams called polymerized high internal phase emulsions…”
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A single short session of media perfusion induces osteogenesis in hBMSCs cultured in porous scaffolds, dependent on cell differentiation stage by Filipowska, Joanna, Reilly, Gwendolen C., Osyczka, Anna M.

“…ABSTRACT Perfusing culture media through porous cell‐seeded scaffolds is now a common approach within many tissue engineering strategies. Human bone‐marrow…”
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Osteocytes and Primary Cilia by Verbruggen, Stefaan W., Sittichokechaiwut, Anuphan, Reilly, Gwendolen C.

“…Purpose of Review The purpose of this review is to provide a background on osteocytes and the primary cilium, discussing the role it plays in osteocyte…”
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Composite porous scaffold of PEG/PLA support improved bone matrix deposition in vitro compared to PLA‐only scaffolds by Bhaskar, Birru, Owen, Robert, Bahmaee, Hossein, Wally, Zena, Sreenivasa Rao, Parcha, Reilly, Gwendolen C.

“…Controllable pore size and architecture are essential properties for tissue‐engineering scaffolds to support cell ingrowth colonization. To investigate the…”
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Emulsion templated scaffolds with tunable mechanical properties for bone tissue engineering by Owen, Robert, Sherborne, Colin, Paterson, Thomas, Green, Nicola H., Reilly, Gwendolen C., Claeyssens, Frederik

“…Polymerised High Internal Phase Emulsions (PolyHIPEs) are manufactured via emulsion templating and exhibit a highly interconnected microporosity. These…”
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Effect of cell sample size in atomic force microscopy nanoindentation by Marcotti, Stefania, Reilly, Gwendolen C, Lacroix, Damien

“…Single-cell technologies are powerful tools to evaluate cell characteristics. In particular, Atomic Force Microscopy (AFM) nanoindentation experiments have…”
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Tendon Fascicle-Inspired Nanofibrous Scaffold of Polylactic acid/Collagen with Enhanced 3D-Structure and Biomechanical Properties by Sensini, Alberto, Gualandi, Chiara, Zucchelli, Andrea, Boyle, Liam A., Kao, Alexander P., Reilly, Gwendolen C., Tozzi, Gianluca, Cristofolini, Luca, Focarete, Maria Letizia

“…Surgical treatment of tendon lesions still yields unsatisfactory clinical outcomes. The use of bioresorbable scaffolds represents a way forward to improve…”
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Design and Assessment of a Dynamic Perfusion Bioreactor for Large Bone Tissue Engineering Scaffolds by Bhaskar, Birru, Owen, Robert, Bahmaee, Hossein, Rao, Parcha Sreenivasa, Reilly, Gwendolen C.

“…Bioreactors can be used to apply fluid flow in vitro to scaffolds to improve mass transport of media and apply mechanical forces to cells. In this study, we…”
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Primary cilia respond to fluid shear stress and mediate flow‐induced calcium deposition in osteoblasts by Delaine‐Smith, Robin M., Sittichokechaiwut, Anuphan, Reilly, Gwendolen C.

“…Bone turnover in vivo is regulated by mechanical forces such as shear stress originating from interstitial oscillatory fluid flow (OFF), and bone cells in…”
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β-glycerophosphate, not low magnitude fluid shear stress, increases osteocytogenesis in the osteoblast-to-osteocyte cell line IDG-SW3 by Owen, Robert, Wittkowske, Claudia, Lacroix, Damien, Perrault, Cecile M, Reilly, Gwendolen C

“…As osteoblasts deposit a mineralized collagen network, a subpopulation of these cells differentiates into osteocytes. Biochemical and mechanical stimuli,…”
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Combined Porogen Leaching and Emulsion Templating to produce Bone Tissue Engineering Scaffolds by Owen, Robert, Sherborne, Colin, Evans, Richard, Reilly, Gwendolen C, Claeyssens, Frederik

“…Bone has a hierarchy of porosity that is often overlooked when creating tissue engineering scaffolds where pore sizes are typically confined to a single order…”
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Shear stress induces osteogenic differentiation of human mesenchymal stem cells by Yourek, Gregory, McCormick, Susan M, Mao, Jeremy J, Reilly, Gwendolen C

“…To determine whether fluid flow-induced shear stress affects the differentiation of bone marrow-derived human mesenchymal stem cells (hMSCs) into osteogenic…”
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Porous Titanium for Dental Implant Applications by Wally, Zena, van Grunsven, William, Claeyssens, Frederik, Goodall, Russell, Reilly, Gwendolen

“…Recently, an increasing amount of research has focused on the biological and mechanical behavior of highly porous structures of metallic biomaterials, as…”
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