Search Results - "Gwadz, R W"

Chloroquine resistance not linked to mdr -like genes in a Plasmodium falciparum cross by Wellems, Thomas E, Panton, Lindsey J, Gluzman, Ilya Y, do Rosario, Virgilio E, Gwadz, Robert W, Walker-Jonah, Annie, Krogstad, Donald J

“…Chloroquine is thought to act against falciparum malaria by accumulating in the acid vesicles of the parasite and interfering with their function. Parasites…”
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Genetic approaches to malaria control: how long the road? by Gwadz, R W

“…Malaria control schemes based on the yet untested concept of replacing vector populations with mosquitoes of the same species unable to transmit the parasite…”
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Effects of magainins and cecropins on the sporogonic development of malaria parasites in mosquitoes by Gwadz, R.W. (National Institute of Allergy and Infectious Diseases, Bethesda, MD), Kaslow, D, Lee, J.Y, Maloy, W.L, Zasloff, M, Miller, L.H

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Genetic selection of a Plasmodium-refractory strain of the malaria vector Anopheles gambiae by Collins, F.H, Sakai, R.K, Vernick, K.D, Paskewitz, S, Seeley, D.C, Miller, L.H, Collins, W.E, Campbell, C.C, Gwadz, R.W

“…The anopheline mosquito is the target in most malaria control programs, primarily through the use of residual insecticides. A mosquito was studied that is…”
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An RFLP map of the Plasmodium falciparum genome, recombination rates and favored linkage groups in a genetic cross by Walker-Jonah, A, Dolan, S A, Gwadz, R W, Panton, L J, Wellems, T E

“…We report a genetic linkage map of the Plasmodium falciparum genome, using the inheritance patterns of nearly 90 RFLP markers in a genetic cross. Markers were…”
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Stable integration and expression of a bacterial gene in the mosquito Anopheles gambiae by Miller, L.H, Sakai, R.K, Romans, P, Gwadz, R.W, Kantoff, P, Coon, H.G

“…Foreign DNA was successfully introduced into the germline of the African mosquito vector of malaria Anopheles gambiae. Stable integration of genes into the…”
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Linkage of a gene causing malaria refractoriness to Diphenol oxidase-A2 on chromosome 3 of Anopheles gambiae by Romans, P, Black, 4th, W C, Sakai, R K, Gwadz, R W

“…An inbred line of the African malaria vector Anopheles gambiae is refractory to development of malaria parasites. It is homozygous for a 4.3-kb Sal I…”
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Demonstration of hypnozoites in sporozoite-transmitted Plasmodium vivax infection by Krotoski, W A, Collins, W E, Bray, R S, Garnham, P C, Cogswell, F B, Gwadz, R W, Killick-Kendrick, R, Wolf, R, Sinden, R, Koontz, L C, Stanfill, P S

“…Hypnozoites of two strains of the human relapsing malaria parasite, Plasmodium vivax, have been detected among maturing 7- and 10-day pre-erythrocytic…”
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Evidence through crossmating experiments of a species complex in Anopheles pseudopunctipennis sensu lato: a primary malaria vector of the American continent by Estrada-Franco, J G, Ma, M C, Gwadz, R W, Sakai, R, Lanzaro, G C, Laughinghouse, A, Galvan-Sanchez, C, Cespedes, J L, Vargas-Sagarnaga, R

“…Crossmating experiments were conducted to determine if postmating reproductive barriers are involved in the maintenance of genetic divergence among populations…”
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Monoclonal antibodies identify the protective antigens of sporozoites of Plasmodium knowlesi by Cochrane, A.H, Santoro, F, Nussenzweig, V, Gwadz, R.W, Nussenzweig, R.S

“…Plasmodium knowlesi, monoclonal antibodies identify protective antigens of sporozoites…”
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A general system of resistance to malaria infection in Anopheles gambiae controlled by two main genetic loci by Vernick, K D, Collins, F H, Gwadz, R W

“…Genetic analysis of a system of Plasmodium refractoriness in Anopheles gambia suggests that the joint action of 2 unlinked genetic loci substantially controls…”
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Plasmodium knowlesi: persistence of transmission blocking immunity in monkeys immunized with gamete antigens by GWADZ, R. W, KOONTZ, L. C

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Use of a restriction fragment length polymorphism (RFLP) as a genetic marker in crosses of Anopheles gambiae (Diptera: Culicidae): independent assortment of a diphenol oxidase RFLP and an esterase locus by Romans, P, Seeley, D C, Kew, Y, Gwadz, R W

“…Analysis of restriction fragment length polymorphism (RFLP) is a powerful tool for analyzing linkage relationships in species where few genetic markers have…”
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Target antigens in malaria transmission blocking immunity by Carter, R, Miller, L H, Rener, J, Kaushal, D C, Kumar, N, Graves, P M, Grotendorst, C A, Gwadz, R W, French, C, Wirth, D

“…Malaria transmission blocking immunity has been found to operate against two distinct phases of development of malaria parasites in the mosquito midgut: (i)…”
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Structural similarities among the protective antigens of sporozoites from different species of malaria parasites by Santoro, F, Cochrane, A H, Nussenzweig, V, Nardin, E H, Nussenzweig, R S, Gwadz, R W, Ferreira, A

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Identification of malaria-infected mosquitoes by a two-site enzyme-linked immunosorbent assay by Burkot, T R, Zavala, F, Gwadz, R W, Collins, F H, Nussenzweig, R S, Roberts, D R

“…A micro enzyme-linked immunosorbent assay (ELISA) for identifying malaria sporozoites in mosquitoes is described. Using an extract of dried infected mosquitoes…”
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Monoclonal antibodies to circumsporozoite proteins identify the species of malaria parasite in infected mosquitoes by Zavala, F, Gwadz, R.W, Collins, F.H, Nussenzweig, R.S, Nussenzweig, V

“…Plasmodium spp., immunoradiometric assays which use monoclonal antibodies to detect circumsporozoite protein antigens can detect, identify, and quantify…”
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Immunogenicity of the repetitive and nonrepetitive peptide regions of the divergent CS protein of Plasmodium knowlesi by Sharma, S, Gwadz, R.W, Schlesinger, D.H, Godson, G.N

“…The circumsporozoite (CS) protein of the Nuri strain of the simian malarial parasite Plasmodium knowlesi was expressed as a fusion protein in E. coli. This…”
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Observations on early and late post-sporozoite tissue stages in primate malaria. IV. Pre-erythrocytic schizonts and/or hypnozoites of Chesson and North Korean strains of Plasmodium vivax in the chimpanzee by Krotoski, W A, Garnham, P C, Cogswell, F B, Collins, W E, Bray, R S, Gwasz, R W, Killick-Kendrick, R, Wolf, R H, Sinden, R, Hollingdale, M

“…In a continuing reexamination of plasmodial tissue stages within the context of the hypnozoite theory of malarial relapse, 2 strains of Plasmodium vivax with…”
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First field trial of an immunoradiometric assay for the detection of malaria sporozoites in mosquitoes by Collins, F H, Zavala, F, Graves, P M, Cochrane, A H, Gwadz, R W, Akoh, J, Nussenzweig, R S

“…An immunoradiometric assay (IRMA) using a monoclonal antibody to the major surface protein of Plasmodium falciparum sporozoites was used to assess the P…”
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