Comparison of Two Frailty Assessment Methods and Their Association with Functionality in Subjects with Exacerbation of COPD

Objectives. To verify the prevalence of frailty in patients hospitalized with acute exacerbation of COPD; to compare two frailty assessment methods: Edmonton Scale and the Fried Frailty Phenotype, and to associate frailty with functioning in these patients. Methods. Patients hospitalized due to an a...

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Published in:	Current gerontology and geriatrics research Vol. 2023; pp. 6660984 - 7
Main Authors:	Morita, Andrea Akemi, Munhoz, Rafaela Furlan, Guzzi, Giovana Labegalini, Probst, Vanessa Suziane
Format:	Journal Article
Language:	English
Published:	United States Hindawi 11-05-2023 John Wiley & Sons, Inc Hindawi Limited
Subjects:	Body mass index Chronic obstructive pulmonary disease Comparative analysis Exercise Frailty Gender Genotype & phenotype Hospitalization Lung diseases, Obstructive Methods Mortality Nutrition Patients Physical fitness Software Spirometry Statistical analysis Walking Womens health Alberta United States > US
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Summary:	Objectives. To verify the prevalence of frailty in patients hospitalized with acute exacerbation of COPD; to compare two frailty assessment methods: Edmonton Scale and the Fried Frailty Phenotype, and to associate frailty with functioning in these patients. Methods. Patients hospitalized due to an acute exacerbation of COPD were included. The assessment of pulmonary function, frailty, and functioning was performed. Frailty assessment was performed by the Edmonton Scale and Fried Frailty Phenotype. Individuals were classified into “frail,” “pre-frail” and “non-frail.” Functioning was evaluated by the one sit-to-stand test. Results. Thirty-five individuals were included (17 male, 69 ± 9 years; FEV1/FVC 47 ± 10%; FEV1 34 (24–52) % predicted). Participants scored 3 (3-4) points on the Edmonton Scale and 7 (5–9) points on the Fried Frailty Phenotype. According to the Fried model, 17% were considered prefrail and 83% frail and in the Edmonton scale, 20% were classified as nonfrail, 29% prefrail, and 51% frail. There was a positive moderate correlation between the two methods (r = 0.42; p=0.011); however, there was no agreement between them (p=0.20). This probably occurs because they assess the same construct, i.e., frailty; however, they are different in their components. There was a negative and moderate correlation between the Fried Frailty Phenotype and functioning (r = −0.43; p=0.009). Conclusion. Most hospitalized individuals with exacerbated COPD with severe and very severe airflow limitation are frail and the assessment methods correlate, but there is no agreement. Additionally, there is association between frailty and functioning in this population.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 Academic Editor: Marco Malavolta
ISSN:	1687-7063 1687-7071
DOI:	10.1155/2023/6660984