Search Results - "Guzman, Norberto A."
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Human Sputum Proteomics: Advancing Non-Invasive Diagnosis of Respiratory Diseases with Enhanced Biomarker Analysis Methods
Published in International journal of translational medicine (31-05-2024)“…Many ailments can be diagnosed while they are asymptomatic, meaning that the patient has no signs or symptoms of a progressing disease. If caught in their…”
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Immunoaffinity Capillary Electrophoresis in the Era of Proteoforms, Liquid Biopsy and Preventive Medicine: A Potential Impact in the Diagnosis and Monitoring of Disease Progression
Published in Biomolecules (Basel, Switzerland) (01-10-2021)“…Over the years, multiple biomarkers have been used to aid in disease screening, diagnosis, prognosis, and response to therapy. As of late, protein biomarkers…”
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Immunoaffinity capillary electrophoresis: A new versatile tool for determining protein biomarkers in inflammatory processes
Published in Electrophoresis (01-06-2011)“…Many diseases caused by inflammatory processes can progress to a chronic state causing deterioration in the quality of life and a poor prognosis for long‐term…”
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A Two-Dimensional Affinity Capture and Separation Mini-Platform for the Isolation, Enrichment, and Quantification of Biomarkers and Its Potential Use for Liquid Biopsy
Published in Biomedicines (30-07-2020)“…Biomarker detection for disease diagnosis, prognosis, and therapeutic response is becoming increasingly reliable and accessible. Particularly, the…”
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Immunoaffinity capillary electrophoresis as a powerful strategy for the quantification of low-abundance biomarkers, drugs, and metabolites in biological matrices
Published in Electrophoresis (01-08-2008)“…In the last few years, there has been a greater appreciation by the scientific community of how separation science has contributed to the advancement of…”
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Improved solid-phase microextraction device for use in on-line immunoaffinity capillary electrophoresis
Published in Electrophoresis (01-11-2003)“…A simple solid‐phase microextraction device was fabricated for use in on‐line immunoaffinity capillary electrophoresis (CE). The device, designed in the form…”
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Advancements in portable instruments based on affinity-capture-migration and affinity-capture-separation for use in clinical testing and life science applications
Published in Journal of Chromatography A (16-08-2023)“…•Point-of-care technologies with affinity-capture steps.•Telehealth integration to connect patients and healthcare providers.•Rapid diagnosis for prompt…”
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Lowering the concentration limits of detection by on-line solid-phase extraction–capillary electrophoresis–electrospray mass spectrometry
Published in Journal of Chromatography A (26-01-2007)“…The use of solid-phase extraction coupled on-line to capillary electrophoresis using electrospray mass spectrometry detection (SPE-CE-ESI-MS) is described for…”
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Affinity capillary electrophoresis: important application areas and some recent developments
Published in Journal of Chromatography B: Biomedical Sciences and Applications (11-09-1998)“…Affinity capillary electrophoresis (ACE) is a broad term referring to the separation by capillary electrophoresis of substances that participate in specific or…”
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Determination of immunoreactive gonadotropin-releasing hormone in serum and urine by on-line immunoaffinity capillary electrophoresis coupled to mass spectrometry
Published in Journal of chromatography. B, Biomedical sciences and applications (01-12-2000)“…The need for urgent diagnoses has propelled the development of automated analyses that can be performed in a short time at reasonable cost. One such method is…”
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An emerging micro-scale immuno-analytical diagnostic tool to see the unseen. Holding promise for precision medicine and P4 medicine
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (15-05-2016)“…•The profile of a miniaturized portable immunoaffinity-based capillary electrophoresis (IACE) instrument is described.•IACE combines the principles of affinity…”
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Remembering Dr. Ernst Kenndler: A Pioneer in Capillary Electrophoresis and Its Basic Principles
Published in Substantia (Firenze) (04-03-2024)“…A great orator has the remarkable ability to captivate their audience and keep their attention. They can break down complex topics into understandable concepts…”
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Analysis of Circulating Forms of proBNP and NT-proBNP in Patients with Severe Heart Failure
Published in Clinical chemistry (Baltimore, Md.) (01-05-2008)“…The specific forms of pro-B-type natriuretic peptide (proBNP) that occur in human blood are not yet clear. We demonstrated the presence of several proBNP forms…”
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Characterization of pharmaceutical drugs by a modified nonaqueous capillary electrophoresis - mass spectrometry method
Published in Electrophoresis (01-01-2003)“…A simple method for the separation and characterization of a group of nine basic compounds, comprising seven tricyclic antidepressant and two bronchodilator…”
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New approaches in clinical chemistry: on-line analyte concentration and microreaction capillary electrophoresis for the determination of drugs, metabolic intermediates, and biopolymers in biological fluids
Published in Journal of Chromatography B: Biomedical Sciences and Applications (12-09-1997)“…The use capillary electrophoresis (CE) for clinically relevant assays in attractive since it often presents many advantages over contemporary methods. The…”
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Immunoaffinity CE for Proteomics Studies
Published in Analytical chemistry (Washington) (01-02-2005)“…A 2-D separation technique can complement MS-based proteomics methods. Guzman and Phillips explain…”
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Immunoaffinity capillary electrophoresis applications of clinical and pharmaceutical relevance
Published in Analytical and bioanalytical chemistry (01-01-2004)Get full text
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Determination of human erythropoietin by on-line immunoaffinity capillary electrophoresis: a preliminary report
Published in Analytical and bioanalytical chemistry (01-04-2007)“…Several CE methodologies have been described for the analysis of rHuEPO in concentrated solutions, but the inherently limited concentration sensitivity of CE…”
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Separation of Recombinant Human Erythropoietin Glycoforms by Capillary Electrophoresis Using Volatile Electrolytes. Assessment of Mass Spectrometry for the Characterization of Erythropoietin Glycoforms
Published in Analytical chemistry (Washington) (01-10-2003)“…The separation of the glycoforms of erythropoietin (EPO) by capillary electrophoresis (CE) was recently published as a monograph by the European Pharmacopoeia…”
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Determination of caffeine and its metabolites in urine by capillary electrophoresis-mass spectrometry
Published in Electrophoresis (01-06-2005)“…The caffeine content of foods and beverages varies considerably, interfering with our ability to obtain valid interpretations in many human studies with regard…”
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