Search Results - "Guzman, Leda"

Synthesis, Anticancer Activity, and Docking Studies of Novel Hydroquinone-Chalcone-Pyrazoline Hybrid Derivatives by Maldonado, Javier, Oliva, Alfonso, Guzmán, Leda, Molinari, Aurora, Acevedo, Waldo

“…A novel series of antitumor hybrids was synthesized using 1,4-benzohydroquinone and chalcone, furane, or pyrazoline scaffolds. This were achieved through…”
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Bioconversion of L-Tyrosine into p- Coumaric Acid by Tyrosine Ammonia-Lyase Heterologue of Rhodobacter sphaeroides Produced in Pseudomonas putida KT2440 by Calderón, Carlos G, Gentina, Juan C, Evrard, Oscar, Guzmán, Leda

“…Coumaric acid ( -CA) is a valuable compound with applications in food additives, cosmetics, and pharmaceuticals. However, traditional production methods are…”
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Genetic diversity and biological activity of Curcuma longa ecotypes from Rapa Nui using molecular markers by Balada, Cristóbal, Castro, Mónica, Fassio, Claudia, Zamora, Agustín, Marchant, María José, Acevedo, Waldo, Guzmán, Leda

“…Curcuma Longa (CL) has been used for hundreds of years by native people from Rapa Nui for the treatment of different illness. Despite this plant was introduced…”
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Involvement of several transcriptional regulators in the differential expression of tfd genes in Cupriavidus necator JMP134 by Trefault, Nicole, Guzmán, Leda, Pérez, Heidi, Godoy, Margarita, González, Bernardo

“…Cupriavidus necator JMP134 has been extensively studied because of its ability to degrade chloroaromatic compounds, including the herbicides…”
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Chemistry and Bioactivity of Microsorum scolopendria (Polypodiaceae): Antioxidant Effects on an Epithelial Damage Model by Balada, Cristóbal, Díaz, Valentina, Castro, Mónica, Echeverría-Bugueño, Macarena, Marchant, María José, Guzmán, Leda

“…Microsorum scolopendia (MS), which grows on the Chilean island of Rapa Nui, is a medicinal fern used to treat several diseases. Despite being widely used, this…”
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High frequency of p16 promoter methylation in non-small cell lung carcinomas from Chile by Guzman, Leda M, Koriyama, Chihaya, Akiba, Suminori, Eizuru, Yoshito, Castillo, Darwins, Corvalan, Alejandro, Aguayo, Francisco R

“…The inactivation of tumour suppressor genes by aberrant methylation of promoter regions has been described as a frequent event in neoplasia development,…”
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In vitro evaluation and molecular docking of QS-21 and quillaic acid from Quillaja saponaria Molina as gastric cancer agents by Guzmán, Leda, Villalón, Katherine, Marchant, María José, Tarnok, María Elena, Cárdenas, Pilar, Aquea, Gisela, Acevedo, Waldo, Padilla, Leandro, Bernal, Giuliano, Molinari, Aurora, Corvalán, Alejandro

“…The cytotoxic mechanism of the saponin QS-21 and its aglycone quillaic acid (QA) was studied on human gastric cancer cells (SNU1 and KATO III). Both compounds…”
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Antiproliferative Benzoindazolequinones as Potential Cyclooxygenase-2 Inhibitors by Molinari, Aurora, Oliva, Alfonso, Arismendi-Macuer, Marlene, Guzmán, Leda, Acevedo, Waldo, Aguayo, Daniel, Vinet, Raúl, San Feliciano, Arturo

“…Quinones and nitrogen heterocyclic moieties have been recognized as important pharmacophores in the development of antitumor agents. This study aimed to…”
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Loss of Expression of Reprimo, a p53-induced Cell Cycle Arrest Gene, Correlates with Invasive Stage of Tumor Progression and p73 Expression in Gastric Cancer by Saavedra, Kathleen, Valbuena, José, Olivares, Wilda, Marchant, María José, Rodríguez, Andrés, Torres-Estay, Verónica, Carrasco-Avino, Gonzalo, Guzmán, Leda, Aguayo, Francisco, Roa, Juan Carlos, Corvalán, Alejandro H

“…Reprimo (RPRM), a downstream effector of p53-induced cell cycle arrest at G2/M, has been proposed as a putative tumor suppressor gene (TSG) and as a potential…”
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Positive Effect of Green Photo-Selective Filter on Graft Union Formation in Tomatoes by Carmach, Constanza, Castro, Monica, Penaloza, Patricia, Guzman, Leda, Marchant, Maria Jose, Valdebenito, Samuel, Kopaitic, Ivan

“…This study investigated the effects of green and red photo-selective filters (shade nets) on the process of graft union formation (healing and acclimation) in…”
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Effects of LED Light Spectra on the Development, Phytochemical Profile, and Antioxidant Activity of Curcuma longa from Easter Island by Marchant, María José, Molina, Paula, Montecinos, Miriam, Guzmán, Leda, Balada, Cristóbal, Castro, Mónica

“…Curcuma longa (C. longa), an herbaceous plant used for medicinal purposes by the indigenous people of Easter Island, has been overexploited in its natural…”
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In Vitro Propagation of Easter Island Curcuma longa from Rhizome Explants Using Temporary Immersion System by Marchant, María José, Molina, Paula, Montecinos, Miriam, Guzmán, Leda, Balada, Cristobal, Fassio, Claudia, Castro, Mónica

“…Curcuma longa (C. longa) is widely known for its medicinal properties. However, the potential overexploitation of this plant raises doubts about its long-term…”
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Analysis of aberrant methylation on promoter sequences of tumor suppressor genes and total DNA in sputum samples: a promising tool for early detection of COPD and lung cancer in smokers by Guzmán, Leda, Depix, María Soledad, Salinas, Ana María, Roldán, Rosa, Aguayo, Francisco, Silva, Alejandra, Vinet, Raul

“…Chronic obstructive pulmonary disease (COPD) is a disorder associated to cigarette smoke and lung cancer (LC). Since epigenetic changes in oncogenes and tumor…”
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Analytical Detection of Immunoglobulin Heavy Chain Gene Rearrangements in Gastric Lymphoid Infiltrates by Peak Area Analysis of the Melting Curve in the LightCycler System by Retamales, Eduardo, Rodriguez, Luis, Guzman, Leda, Aguayo, Francisco, Palma, Mariana, Backhouse, Claudia, Argandona, Jorge, Riquelme, Erick, Corvalan, Alejandro

“…Because it is difficult to differentiate gastric mucosa-associated lymphoid tissue (MALT) lymphoma from chronic gastritis in gastric lymphoid infiltrates,…”
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Diversity of Culturable Bacteria from Endemic Medicinal Plants of the Highlands of the Province of Parinacota, Chile by Moraga, Daniel, Latorre, Katina, Muñoz-Torres, Patricio, Cárdenas, Steffany, Jofré-Quispe, Alan, López-Cepeda, José, Bustos, Luis, Balada, Cristóbal, Argaluza, María Fernanda, González, Pablo, Guzmán, Leda

“…Endemic medicinal plants that grow at altitudes in northern Chile have been traditionally used for therapeutic applications by Aymara doctors. Several studies…”
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New 1H-Benzo[f]indazole-4,9-diones Conjugated with C-Protected Amino Acids and Other Derivatives: Synthesis and in Vitro Antiproliferative Evaluation by Molinari, Aurora, Oliva, Alfonso, Arismendi-Macuer, Marlene, Guzmán, Leda, Fuentealba, Mauricio, Knox, Marcela, Vinet, Raúl, San Feliciano, Arturo

“…1H-Benzo[f]indazole-4,9-dione derivatives conjugated with C-protected amino acids (glycine, l-alanine, l-phenylalanine and l-glutamic acid) 6a-l were prepared…”
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t-Resveratrol Protects against Acute High Glucose Damage in Endothelial Cells by Guzmán, Leda, Balada, Cristóbal, Flores, Guillermo, Álvarez, Rocío, Knox, Marcela, Vinet, Raúl, Martínez, José L.

“…Postprandial hyperglycemia in diabetic and nondiabetic subjects is associated with endothelial dysfunction. Evidence shows that high glucose generates…”
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Gold@Silica Nanoparticles Functionalized with Oligonucleotides: A Prominent Tool for the Detection of the Methylated Reprimo Gene in Gastric Cancer by Dynamic Light Scattering by Marchant, María José, Guzmán, Leda, Corvalán, Alejandro H., Kogan, Marcelo J.

“…Reprimo (RPRM) is a tumor suppressor gene involved in the development of gastric cancer. Hypermethylation of the RPRM promoter region has been found in tumor…”
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Sa1934 Loss of Expression by Aberrant Hypermethylation of Reprimo in the Multistep Cascade of Gastric Cancer by Nicole, Roldán, Fry, Jacqueline, Cerda, Paulina, José, Marchant María, Alarcon, Alejandra, Leda, Guzmán M, Aravena, Edmundo, Barrientos, Carlos, Calvo, Alfonso, Corvalan, Alejandro H

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Su1986 Epigenetic and Genetic Inactivation of the E-Cadherin Gene in Sporadic Diffuse-Type Gastric Garcinoma by Corvalan, Alejandro H, Olivares, Wilda, Bernal, Carolina, Maturana, María J, Guzman, Leda

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