Search Results - "Guzman, Georgianna S."

Assembly of dimeric myeloperoxidase during posttranslational maturation in human leukemic HL-60 cells by Taylor, Kathryn L, Guzman, Georgianna S, Burgess, Carol A, Kinkade, Joseph M

“…Myeloperoxidase is a major protein component of the azurophilic granules (specialized lysosomes) of normal human neutrophils and serves as part of a potent…”
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Peritoneal macrophages of pathogen-free rats but not of conventional rats secrete elastolytic activity by Goodrum, K J, Guzman, G S, Lindsey, J R, Silberman, M, Spitznagel, J K

“…Elicited peritoneal macrophages from Sprague-Dawley rats conventionally bred and housed failed, as we have reported, to produce detectable elastolytic activity…”
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The post-translational processing of myeloperoxidase is regulated by the availability of heme by Pinnix, I B, Guzman, G S, Bonkovsky, H L, Zaki, S R, Kinkade, Jr, J M

“…Myeloperoxidase (MPO) is a hemoprotein that is synthesized in the lumen of the endoplasmic reticulum (ER) as a single-chain precursor and undergoes a complex…”
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Distinct chromatographic forms of human hemi-myeloperoxidase obtained by reductive cleavage of the dimeric enzyme. Evidence for subunit heterogeneity by K L Taylor, G S Guzman, J Pohl, J M Kinkade, Jr

“…The enzyme myeloperoxidase (MPO) is a functionally important glycoprotein of neutrophilic granulocytes and occurs in three major isoforms (forms 1, 2, and 3)…”
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The Ontogeny of a 57-Kd Cationic Antimicrobial Protein of Human Polymorphonuclear Leukocytes: Localization to a Novel Granule Population by Pereira, H.Anne, Spitznagel, John K., Winton, Elliott F., Shafer, William M., Martin, Larry E., Guzman, Georgianna S., Pohl, Jan, Scott, Randy W., Marra, Marian N., Kinkade, Joseph M.

“…The ontogeny of a 57-Kd cationic antimicrobial protein (CAP57) that has substantial similarities to bactericidal permeability increasing protein (BPI) has been…”
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