Search Results - "Guyotat, Denis"

An miRNA-DNMT1 Axis Is Involved in Azacitidine Resistance and Predicts Survival in Higher-Risk Myelodysplastic Syndrome and Low Blast Count Acute Myeloid Leukemia by Solly, Françoise, Koering, Catherine, Mohamed, Aminetou Mint, Maucort-Boulch, Delphine, Robert, Guillaume, Auberger, Patrick, Flandrin-Gresta, Pascale, Adès, Lionel, Fenaux, Pierre, Kosmider, Olivier, Tavernier-Tardy, Emmanuelle, Cornillon, Jérôme, Guyotat, Denis, Campos, Lydia, Mortreux, Franck, Wattel, Eric

“…Azacitidine inhibits DNA methyltransferases, including DNMT1, and is currently the standard of care for patients with higher-risk myelodysplastic syndrome…”
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European experience and risk factor analysis of donor cell-derived leukaemias/MDS following haematopoietic cell transplantation by Engel, Nicole, Rovo, Alicia, Badoglio, Manuela, Labopin, Myriam, Basak, Grzegorz W., Beguin, Yves, Guyotat, Denis, Ljungman, Per, Nagler, Arnon, Schattenberg, Anton, Schroeder, Thomas, Schroyens, Wilfried, Tischer, Johanna, Socie, Gerard, Kolb, Hans-Jochem, Tichelli, Andre, Salooja, Nina, Duarte, Rafael F.

“…Donor cell leukaemia (DCL) is a rare complication of allogeneic haematopoietic cell transplantation (HCT). We have investigated the prevalence and outcome of…”
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Efficiency of nilotinib to target chronic phase-chronic myeloid leukaemia primary mature CD34− and immature CD34+ cells by Berger, Marc G., Lebecque, Benjamin, Tassin, Thomas, Dannus, Louis-Thomas, Berger, Juliette, Soucal, Mélanie, Guerci, Agnès, Cony-Makhoul, Pascale, Johnson, Hyacinthe, Etienne, Gabriel, Guyotat, Denis, Gagnieu, Marie-Claude, Pereira, Bruno, Saugues, Sandrine, Tournilhac, Olivier, Hermet, Eric, Bourgne, Céline

“…Accumulation in target cells is an essential pharmacokinetic step of targeted therapies. Tyrosine Kinase Inhibitors (TKI) against the BCR-ABL fusion protein in…”
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Use of Complementary and Alternative Medicines among Cancer Patients: A Single-Center Study by Gras, Mathilde, Vallard, Alexis, Brosse, Christelle, Beneton, Aurélie, Sotton, Sandrine, Guyotat, Denis, Fournel, Pierre, Daguenet, Elisabeth, Magné, Nicolas, Morisson, Stéphanie

“…It is usual for cancer patients to use complementary and alternative medicines (CAMs) and yet the literature evaluating their efficacy in cancer patients is…”
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Natural Killer Cell Subpopulations and Inhibitory Receptor Dynamics in Myelodysplastic Syndromes and Acute Myeloid Leukemia by Cianga, Vlad Andrei, Campos Catafal, Lydia, Cianga, Petru, Pavel Tanasa, Mariana, Cherry, Mohamad, Collet, Phillipe, Tavernier, Emmanuelle, Guyotat, Denis, Rusu, Cristina, Aanei, Carmen Mariana

“…Natural killer (NK) cells are key innate immunity effectors that play a major role in malignant cell destruction. Based on expression patterns of CD16, CD56,…”
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Recurrent Mutations of the Active Adenylation Domain of UBA1 in Atypical Form of VEXAS Syndrome by Faurel, Alyx, Heiblig, Maël, Kosmider, Olivier, Cornillon, Jérôme, Boudou, Laurence, Guyotat, Denis, Martignoles, Jean‐Alain, Jamilloux, Yvan, Noyel, Pauline, Daguenet, Elisabeth, Faure, Anne‐Camille, Sujobert, Pierre, Flandrin‐Gresta, Pascale

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Database-Guided Analysis for Immunophenotypic Diagnosis and Follow-Up of Acute Myeloid Leukemia With Recurrent Genetic Abnormalities by Aanei, Carmen-Mariana, Veyrat-Masson, Richard, Selicean, Cristina, Marian, Mirela, Rigollet, Lauren, Trifa, Adrian Pavel, Tomuleasa, Ciprian, Serban, Adrian, Cherry, Mohamad, Flandrin-Gresta, Pascale, Tardy, Emmanuelle Tavernier, Guyotat, Denis, Campos Catafal, Lydia

“…Acute myeloid leukemias (AMLs) are hematologic malignancies with varied molecular and immunophenotypic profiles, making them difficult to diagnose and…”
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External validation of the MidiCAT variant of thrombography: Comparison with calibrated automated thrombography and study of the centrifugation scheme by Charles, Sebastien, Guyotat, Denis, Fontana, Pierre, Tardy, Bernard, Lecompte, Thomas, Chalayer, Emilie

“…Introduction To perform Calibrated Automated Thrombography (CAT), the use of reduced plasma volumes (referred to as “MidiCAT”) makes it possible to more…”
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Evaluation by Flow Cytometry of Mature Monocyte Subpopulations for the Diagnosis and Follow-Up of Chronic Myelomonocytic Leukemia by Picot, Tiphanie, Aanei, Carmen Mariana, Flandrin Gresta, Pascale, Noyel, Pauline, Tondeur, Sylvie, Tavernier Tardy, Emmanuelle, Guyotat, Denis, Campos Catafal, Lydia

“…Chronic myelomonocytic leukemia (CMML) is a myelodysplastic/myeloproliferative neoplasm, characterized by persistent monocytosis and dysplasia in at least one…”
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Editorial: A Revised Approach to the Pathogenesis and Diagnosis of Myelodysplastic Syndromes With Therapeutic Implications by Aanei, Carmen Mariana, Campos Catafal, Lydia, Guyotat, Denis

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Expression of embryonic stem cell markers in acute myeloid leukemia by Picot, Tiphanie, Aanei, Carmen Mariana, Fayard, Amandine, Flandrin-Gresta, Pascale, Tondeur, Sylvie, Gouttenoire, Marina, Tavernier-Tardy, Emmanuelle, Wattel, Eric, Guyotat, Denis, Campos, Lydia

“…Acute myeloid leukemia is driven by leukemic stem cells which can be identified by cross lineage expression or arrest of differentiation compared to normal…”
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DNA methylation profiling reveals a pathological signature that contributes to transcriptional defects of CD34+CD15− cells in early chronic‐phase chronic myeloid leukemia by Maupetit‐Mehouas, Stéphanie, Court, Franck, Bourgne, Céline, Guerci‐Bresler, Agnès, Cony‐Makhoul, Pascale, Johnson, Hyacinthe, Etienne, Gabriel, Rousselot, Philippe, Guyotat, Denis, Janel, Alexandre, Hermet, Eric, Saugues, Sandrine, Berger, Juliette, Arnaud, Philippe, Berger, Marc G.

“…Despite the high efficiency of tyrosine kinase inhibitors (TKI), some patients with chronic myeloid leukemia (CML) will display residual disease that can…”
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Impaired Expression of Focal Adhesion Kinase in Mesenchymal Stromal Cells from Low-Risk Myelodysplastic Syndrome Patients by Wu, Yuenv, Aanei, Carmen Mariana, Kesr, Sanae, Picot, Tiphanie, Guyotat, Denis, Campos Catafal, Lydia

“…The pathogenic role of mesenchymal stromal cells (MSCs) in myelodysplastic syndromes (MDS) development and progression has been investigated by numerous…”
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Advanced Flow Cytometry Analysis Algorithms for Optimizing the Detection of “Different From Normal” Immunophenotypes in Acute Myeloid Blasts by Aanei, Carmen-Mariana, Veyrat-Masson, Richard, Rigollet, Lauren, Stagnara, Jérémie, Tavernier Tardy, Emmanuelle, Daguenet, Elisabeth, Guyotat, Denis, Campos Catafal, Lydia

“…Acute myeloid leukemias (AMLs) are a group of hematologic malignancies that are heterogeneous in their molecular and immunophenotypic profiles. Identification…”
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Significance of Heat-Shock Protein (HSP) 90 Expression in Acute Myeloid Leukemia Cells by Flandrin, Pascale, Guyotat, Denis, Duval, Amélie, Cornillon, Jérôme, Tavernier, Emmanuelle, Nadal, Nathalie, Campos, Lydia

“…The 90-kDa heat shock protein (HSP90) is implicated in the conformational maturation and stabilization of a variety of client proteins with receptor and signal…”
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Fulminant hepatitis due to very severe sinusoidal obstruction syndrome (SOS/VOD) after autologous peripheral stem cell transplantation: a case report by Tavernier, Emmanuelle, Chalayer, Emilie, Cornillon, Jérôme, Pouvaret, Anne, Martignoles, Jean-Alain, Casteillo, François, Terreaux, Jérémy, Daguenet, Elisabeth, Guyotat, Denis

“…Hepatic veno-occlusive disease, also called sinusoidal obstruction syndrome (SOS/VOD), is a potentially fatal complication of allogeneic or autologous…”
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Prognostic value of CXCR4 and FAK expression in acute myelogenous leukemia by Tavernier-Tardy, Emmanuelle, Cornillon, Jérôme, Campos, Lydia, Flandrin, Pascale, Duval, Amélie, Nadal, Nathalie, Guyotat, Denis

“…Abstract We analysed, by flow cytometry, the “adhesive” phenotype of acute myelogenous leukemia (AML) cells from 36 patients treated in our institution. In…”
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Focal adhesion protein abnormalities in myelodysplastic mesenchymal stromal cells by Aanei, Carmen Mariana, Eloae, Florin Zugun, Flandrin-Gresta, Pascale, Tavernier, Emmanuelle, Carasevici, Eugen, Guyotat, Denis, Campos, Lydia

“…Direct cell–cell contact between haematopoietic progenitor cells (HPCs) and their cellular microenvironment is essential to maintain ‘stemness’. In cancer…”
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FAK Deficiency in Bone Marrow Stromal Cells Alters Their Homeostasis and Drives Abnormal Proliferation and Differentiation of Haematopoietic Stem Cells by Wu, Yuenv, Campos, Lydia, Daguenet, Elisabeth, He, Zhiguo, Picot, Tiphanie, Tavernier-Tardy, Emmanuelle, Soglu, Gilbert, Guyotat, Denis, Aanei, Carmen-Mariana

“…Emerging evidence indicates that in myelodysplastic syndromes (MDS), the bone marrow (BM) microenvironment may also contribute to the ineffective, malignant…”
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Impact of ATG Dose on the Outcome of Patients Undergoing Reduced Intensity Conditioning Followed by Allogeneic Hematopoietic Stem Cell Transplantation for Hematological Malignancies by Cornillon, Jérôme, Balsat, Marie, Cabrespine, Aurélie, Tavernier-Tardy, Emmanuelle, Hermet, Eric, Mulliez, Aurélien, Augeul-Meunier, Karine, Guyotat, Denis, Bay, Jacques-Olivier

“…Reduced intensity conditioning for allogeneic hematopoietic stem cell transplantation (allo-HSCT) is often proposed for patients with comorbidities. To enhance…”
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