Search Results - "Guyon, Frédéric"

PatchSearch: A Fast Computational Method for Off-Target Detection by Rasolohery, Inès, Moroy, Gautier, Guyon, Frédéric

“…Many therapeutic molecules are known to bind several proteins, which can be different from the initially targeted one. Such unexpected interactions with…”
Get full text

European Society of Gynecological Oncology Statement on Fibroid and Uterine Morcellation by Halaska, Michael J, Haidopoulos, Dimitrios, Guyon, Frédéric, Morice, Philippe, Zapardiel, Ignacio, Kesic, Vesna

“…Recently, there has been an intense discussion about the issue of fibroid and uterine morcellation in relation to the risk of unrecognized uterine sarcoma…”
Get more information

Therapeutic Management and Prognostic Factors for Ovarian Malignant Tumours in Adolescents: A Comprehensive Review of Current Guidelines by Margioula-Siarkou, Chrysoula, Petousis, Stamatios, Margioula-Siarkou, Georgia, Mavromatidis, George, Chatzinikolaou, Fotios, Hatzipantelis, Emmanouel, Guyon, Frédéric, Dinas, Konstantinos

“…Ovarian malignant tumours are rarely diagnosed in adolescents but may have a significant impact on their survival, future fertility and quality of life. The…”
Get full text

Molecular Characterization of Ovarian Yolk Sac Tumor (OYST) by Hodroj, Khalil, Stevovic, Aleksandra, Attignon, Valery, Ferraioli, Domenico, Meeus, Pierre, Croce, Sabrina, Chopin, Nicolas, Rossi, Lea, Floquet, Anne, Rousset-Jablonski, Christine, Tredan, Olivier, Guyon, Frédéric, Treilleux, Isabelle, Rannou, Corinne, Morfouace, Marie, Ray-Coquard, Isabelle

“…Most patients with malignant ovarian germ cell tumors (MOGTCs) have a very good prognosis and chemotherapy provides curative treatment; however, patients with…”
Get full text

Pelvic insufficiency fractures after intensity modulated radiation therapy combined with chemotherapy for cervix carcinoma: Incidence and impact of bone mineral density by Duranson, Agathe, Thevenet, Vincent, Guyon, Frédéric, Babin, Guillaume, Lebreton, Coriolan, Renaud, Tiphaine, Gaillard, Anne-Lise, Dupuy, Quentin, Bouleftour, Wafa, Magne, Nicolas, Petit, Adeline

“…•18.4% patients of this cohort experienced Pelvic Insufficiency Fractures (PIFs), which indicate that this complication is not so rare affecting one in 5…”
Get full text

BCSearch: fast structural fragment mining over large collections of protein structures by Guyon, Frédéric, Martz, François, Vavrusa, Marek, Bécot, Jérôme, Rey, Julien, Tufféry, Pierre

“…Resources to mine the large amount of protein structures available today are necessary to better understand how amino acid variations are compatible with…”
Get full text

Effect of tumor burden and radical surgery on survival difference between upfront, early interval or delayed cytoreductive surgery in ovarian cancer by Angeles, Martina Aida, Cabarrou, Bastien, Gil-Moreno, Antonio, Pérez-Benavente, Asunción, Spagnolo, Emanuela, Rychlik, Agnieszka, Martínez-Gómez, Carlos, Guyon, Frédéric, Zapardiel, Ignacio, Querleu, Denis, Illac, Claire, Migliorelli, Federico, Bétrian, Sarah, Ferron, Gwénaël, Hernández, Alicia, Martinez, Alejandra

“…We sought to evaluate the impact on survival of tumor burden and surgical complexity in relation to the number of cycles of neoadjuvant chemotherapy (NACT) in…”
Get full text

Cost-effectiveness analysis of simple hysterectomy compared to radical hysterectomy for early cervical cancer: analysis from the GCIG/CCTG CX.5/SHAPE trial by Kwon, Janice S, McTaggart-Cowan, Helen, Ferguson, Sarah E, Samouëlian, Vanessa, Lambaudie, Eric, Guyon, Frédéric, Tidy, John, Williamson, Karin, Gleeson, Noreen, de Kroon, Cor, van Driel, Willemien, Mahner, Sven, Hanker, Lars, Goffin, Frédéric, Berger, Regina, Eyjólfsdóttir, Brynhildur, Kim, Jae-Weon, Brotto, Lori A, Pataky, Reka, Yeung, Shirley S T, Chan, Kelvin K W, Cheung, Matthew C, Ubi, Juliana, Tu, Dongsheng, Shepherd, Lois E, Plante, Marie

“…SHAPE (Simple Hysterectomy And PElvic node assessment) was an international phase III trial demonstrating that simple hysterectomy was non-inferior to radical…”
Get full text

Uterine and vaginal sarcomas resembling fibrosarcoma: a clinicopathological and molecular analysis of 13 cases showing common NTRK-rearrangements and the description of a COL1A1-PDGFB fusion novel to uterine neoplasms by Croce, Sabrina, Hostein, Isabelle, Longacre, Teri A., Mills, Anne M., Pérot, Gaëlle, Devouassoux-Shisheboran, Mojgan, Velasco, Valérie, Floquet, Anne, Guyon, Frédéric, Chakiba, Camille, Querleu, Denis, Khalifa, Emmanuel, Mayeur, Laetitia, Rebier, Flora, Leguellec, Sophie, Soubeyran, Isabelle, McCluggage, W. Glenn

“…Mesenchymal neoplasms of the uterus (corpus and cervix) encompass a heterogeneous group of tumors with differing morphologies, immunophenotypes and molecular…”
Get full text

Analysis of the copy number profiles of several tumor samples from the same patient reveals the successive steps in tumorigenesis by Letouzé, Eric, Allory, Yves, Bollet, Marc A, Radvanyi, François, Guyon, Frédéric

“…We present a computational method, TuMult, for reconstructing the sequence of copy number changes driving carcinogenesis, based on the analysis of several…”
Get full text

PEP-FOLD: an updated de novo structure prediction server for both linear and disulfide bonded cyclic peptides by Thévenet, Pierre, Shen, Yimin, Maupetit, Julien, Guyon, Frédéric, Derreumaux, Philippe, Tufféry, Pierre

“…In the context of the renewed interest of peptides as therapeutics, it is important to have an on-line resource for 3D structure prediction of peptides with…”
Get full text

DaReUS-Loop: accurate loop modeling using fragments from remote or unrelated proteins by Karami, Yasaman, Guyon, Frédéric, De Vries, Sjoerd, Tufféry, Pierre

“…Despite efforts during the past decades, loop modeling remains a difficult part of protein structure modeling. Several approaches have been developed in the…”
Get full text

TRUST: Trial of Radical Upfront Surgical Therapy in advanced ovarian cancer (ENGOT ov33/AGO-OVAR OP7) by Reuss, Alexander, du Bois, Andreas, Harter, Philipp, Fotopoulou, Christina, Sehouli, Jalid, Aletti, Giovanni, Guyon, Frederic, Greggi, Stefano, Mosgaard, Berit Jul, Reinthaller, Alexander, Hilpert, Felix, Schade-Brittinger, Carmen, Chi, Dennis S, Mahner, Sven

“…Primary cytoreductive surgery followed by chemotherapy has been considered standard management for patients with advanced ovarian cancer over decades. An…”
Get more information

SA-Search: a web tool for protein structure mining based on a Structural Alphabet by Guyon, Frédéric, Camproux, Anne-Claude, Hochez, Joëlle, Tufféry, Pierre

“…SA-Search is a web tool that can be used to mine for protein structures and extract structural similarities. It is based on a hidden Markov model derived…”
Get full text

PatchSearch: a web server for off-target protein identification by Rey, Julien, Rasolohery, Inès, Tufféry, Pierre, Guyon, Frédéric, Moroy, Gautier

“…The large number of proteins found in the human body implies that a drug may interact with many proteins, called off-target proteins, besides its intended…”
Get full text

Genome profiling is an efficient tool to avoid the STUMP classification of uterine smooth muscle lesions: a comprehensive array-genomic hybridization analysis of 77 tumors by Croce, Sabrina, Ducoulombier, Agnès, Ribeiro, Agnès, Lesluyes, Tom, Noel, Jean-Christophe, Amant, Frédéric, Guillou, Louis, Stoeckle, Eberhard, Devouassoux-Shisheboran, Mojgan, Penel, Nicolas, Floquet, Anne, Arnould, Laurent, Guyon, Frédéric, Mishellany, Florence, Chakiba, Camille, Cuppens, Tine, Zikan, Michal, Leroux, Agnès, Frouin, Eric, Farre, Isabelle, Genestie, Catherine, Valo, Isabelle, MacGrogan, Gaëtan, Chibon, Frédéric

“…The diagnosis of a uterine smooth muscle lesion is, in the majority of cases, straightforward. However, in a small number of cases, the morphological criteria…”
Get full text

Fast protein fragment similarity scoring using a Binet-Cauchy kernel by Guyon, Frédéric, Tufféry, Pierre

“…Meaningful scores to assess protein structure similarity are essential to decipher protein structure and sequence evolution. The mining of the increasing…”
Get full text

Use of uterine manipulator in endometrial cancer: A French survey from Francogyn group by Sallee, Camille, Lacorre, Aymeline, Despoux, France, Ouldamer, Lobna, Huchon, Cyrille, Koskas, Martin, Classe, Jean-Marc, Guyon, Frédéric, Margueritte, François, Raimond, Emilie, Gauthier, Tristan

“…Since the LACC study in 2018, the use of the uterine manipulator (UM) has been questioned in Oncological surgery. Nowadays, there are few data on UM use in…”
Get full text

DIONYSUS: a database of protein-carbohydrate interfaces by Gheeraert, Aria, Bailly, Thomas, Ren, Yani, Hamraoui, Ali, Te, Julie, Vander Meersche, Yann, Cretin, Gabriel, Leon Foun Lin, Ravy, Gelly, Jean-Christophe, Pérez, Serge, Guyon, Frédéric, Galochkina, Tatiana

“…Protein-carbohydrate interactions govern a wide variety of biological processes and play an essential role in the development of different diseases. Here, we…”
Get full text

Uterine sarcomas and rare uterine mesenchymal tumors with malignant potential. Diagnostic guidelines of the French Sarcoma Group and the Rare Gynecological Tumors Group by Croce, Sabrina, Devouassoux-Shisheboran, Mojgan, Pautier, Patricia, Ray-Coquard, Isabelle, Treilleux, Isabelle, Neuville, Agnès, Arnould, Laurent, Just, Pierre-Alexandre, Belda, Marie Aude Le Frere, Averous, Gerlinde, Leroux, Agnès, Mery, Eliane, Loussouarn, Delphine, Weinbreck, Nicolas, Le Guellec, Sophie, Mishellany, Florence, Morice, Philippe, Guyon, Frédéric, Genestie, Catherine

“…The landscape of uterine sarcomas is becoming increasingly complex with the description of new entities associated with recurrent molecular alterations…”
Get full text