Search Results - "Guy, V"
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Handhold-Mediated Strand Displacement: A Nucleic Acid Based Mechanism for Generating Far-from-Equilibrium Assemblies through Templated Reactions
Published in ACS nano (23-02-2021)“…The use of templates is a well-established method for the production of sequence-controlled assemblies, particularly long polymers. Templating is canonically…”
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IL-2 is a critical regulator of group 2 innate lymphoid cell function during pulmonary inflammation
Published in Journal of allergy and clinical immunology (01-12-2015)“…Background Group 2 innate lymphoid cells (ILC2) have been implicated in the pathogenesis of allergic lung diseases. However, the upstream signals that regulate…”
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3
In situ Generation of RNA Complexes for Synthetic Molecular Strand-Displacement Circuits in Autonomous Systems
Published in Nano letters (13-01-2021)“…Synthetic molecular circuits implementing DNA or RNA strand-displacement reactions can be used to build complex systems such as molecular computers and…”
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Can the Cartilaginous Thickness Determine the Risk of Malignancy in Pelvic Cartilaginous Tumors, and How Accurate is the Preoperative Biopsy of These Tumors?
Published in Clinical orthopaedics and related research (01-06-2024)“…Peripheral osteochondral tumors are common, and the management of tumors presenting in the pelvis is challenging and a controversial topic. Some have suggested…”
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PIC micro-controller based synchronization of two fractional order jerk systems
Published in Scientific reports (22-08-2022)“…The paper studies a 3D Chaotic Jerk oscillator with fractional derivatives. An approach is proposed to implement it on a PIC16F877A microcontroller in order to…”
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Teaching hydrogen bridges: it is not FON anymore
Published in Chemistry Teacher International : best practices in chemistry education (24-09-2024)“…Teaching hydrogen bridges (H-bridges) in introductory chemistry courses is either oversimplified or dogmatically taught; the heuristic that ‘only fluorine,…”
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Pelvic bone sarcomas, prognostic factors, and treatment: A narrative review of the literature
Published in Scandinavian Journal of Surgery (01-09-2023)“…Primary sarcomas of bone are rare malignant mesenchymal tumors. The most common bone sarcomas are osteosarcoma, Ewing’s sarcoma, and chondrosarcoma. The…”
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SBOL Visual: A Graphical Language for Genetic Designs
Published in PLoS biology (01-12-2015)“…Synthetic Biology Open Language (SBOL) Visual is a graphical standard for genetic engineering. It consists of symbols representing DNA subsequences, including…”
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Novel one-pot synthesis of a library of 2-aryloxy-1,4-naphthoquinone derivatives. Determination of antifungal and antibacterial activity
Published in RSC advances (23-06-2022)“…The development of new antibiotics and inexpensive antifungals is an important field of research. Based on the privileged pharmacophore of lawsone, a series of…”
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Selective Treg reconstitution during lymphopenia normalizes DC costimulation and prevents graft-versus-host disease
Published in The Journal of clinical investigation (01-09-2015)“…Regulatory T cells (Tregs) have been shown to enhance immune reconstitution and prevent graft-versus-host disease (GVHD) after hematopoietic stem cell…”
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Tuning the dials of Synthetic Biology
Published in Microbiology (Society for General Microbiology) (01-07-2013)“…Synthetic Biology is the 'Engineering of Biology' - it aims to use a forward-engineering design cycle based on specifications, modelling, analysis,…”
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MHCII restriction demonstrates B cells have very limited capacity to activate tumour-specific CD4 + T cells in vivo
Published in Oncoimmunology (31-12-2024)“…There has been growing interest in the role of B cells in antitumour immunity and potential use in adoptive cellular therapies. To date, the success of such…”
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Low Pretreatment CD4+:CD8+ T Cell Ratios and CD39+CD73+CD19+ B Cell Proportions Are Associated with Improved Relapse-Free Survival in Head and Neck Squamous Cell Carcinoma
Published in International journal of molecular sciences (01-08-2023)“…The ectonucleotidases CD39 and CD73 are present on immune cells and play important roles in cancer progression by suppressing antitumour immunity. As such,…”
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Intracellular delivery of biologic therapeutics by bacterial secretion systems
Published in Expert reviews in molecular medicine (06-04-2017)“…Biologics are a promising new class of drugs based on complex macromolecules such as proteins and nucleic acids. However, delivery of these macromolecules into…”
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Neuromuscular monitoring, reversal and postoperative residual neuromuscular block: An intradepartmental survey over the years
Published in Anaesthesia and intensive care (01-01-2020)“…Residual neuromuscular block (NMB) may persist in the post-anaesthesia care unit (PACU).1 Studies in our department found that our incidence of postoperative…”
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Building an RNA-Based Toggle Switch Using Inhibitory RNA Aptamers
Published in ACS synthetic biology (18-02-2022)“…Synthetic RNA systems offer unique advantages such as faster response, increased specificity, and programmability compared to conventional protein-based…”
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Synthetic gene circuits for metabolic control: design trade-offs and constraints
Published in Journal of the Royal Society interface (06-01-2013)“…A grand challenge in synthetic biology is to push the design of biomolecular circuits from purely genetic constructs towards systems that interface different…”
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Chondrosarcoma of the Femur: Is Local Recurrence Influenced by the Presence of an Extraosseous Component?
Published in Cancers (01-01-2024)“…Chondrosarcoma (CS) is the second most common surgically treated primary malignancy of the bone. The current study explored the effect of the margin and…”
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Noise Propagation in Synthetic Gene Circuits for Metabolic Control
Published in ACS synthetic biology (20-02-2015)“…Dynamic control of enzyme expression can be an effective strategy to engineer robust metabolic pathways. It allows a synthetic pathway to self-regulate in…”
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Indirect Dynamic Negotiation in the Nash Demand Game
Published in IEEE access (2022)“…The paper addresses a problem of sequential bilateral bargaining with incomplete information. We proposed a decision model that helps agents to successfully…”
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