Search Results - "Guy, Reut"

Promising Opportunities for Treating Neurodegenerative Diseases with Mesenchymal Stem Cell-Derived Exosomes by Guy, Reut, Offen, Daniel

“…Neurodegenerative disease refers to any pathological condition in which there is a progressive decline in neuronal function resulting from brain atrophy…”
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Mesenchymal Stem Cell-Derived Extracellular Vesicles as Proposed Therapy in a Rat Model of Cerebral Small Vessel Disease by Guy, Reut, Herman, Shay, Benyamini, Hadar, Ben-Zur, Tali, Kobo, Hila, Pasmanik-Chor, Metsada, Yaacobi, Dafna, Barel, Eric, Yagil, Chana, Yagil, Yoram, Offen, Daniel

“…Mesenchymal stem cell-derived extracellular vesicles (MSC-EVs) have been employed in the past decade as therapeutic agents in various diseases, including…”
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A Novel Rodent Model of Hypertensive Cerebral Small Vessel Disease with White Matter Hyperintensities and Peripheral Oxidative Stress by Guy, Reut, Volkman, Rotem, Wilczynski, Ella, Yagil, Chana, Yagil, Yoram, Findler, Michael, Auriel, Eitan, Nevo, Uri, Offen, Daniel

“…Cerebral small vessel disease (CSVD) is the second most common cause of stroke and a major contributor to dementia. Manifestations of CSVD include cerebral…”
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Human Muscle Progenitor Cells Overexpressing Neurotrophic Factors Improve Neuronal Regeneration in a Sciatic Nerve Injury Mouse Model by Guy, Reut, Grynspan, Frida, Ben-Zur, Tali, Panski, Avraham, Lamdan, Ron, Danon, Uri, Yaffe, David, Offen, Daniel

“…The peripheral nervous system has an intrinsic ability to regenerate after injury. However, this process is slow, incomplete, and often accompanied by…”
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Extracellular vesicles over adeno-associated viruses: Advantages and limitations as drug delivery platforms in precision medicine by Yom-Tov, Nataly, Guy, Reut, Offen, Daniel

“…Tissue-specific uptake and sufficient biodistribution are central goals in drug development. Crossing the blood-brain barrier (BBB) represents a major…”
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