Search Results - "Guy, Carol A"

Identification and Analysis of the Promoter Region of the Human Hyaluronan Synthase 2 Gene by Monslow, Jamie, Williams, John D, Guy, Carol A, Price, Iain K, Craig, Kathrine J, Williams, Hywel J, Williams, Nigel M, Martin, John, Coleman, Sharon L, Topley, Nicholas, Spicer, Andrew P, Buckland, Paul R, Davies, Malcolm, Bowen, Timothy

“…Hyaluronan (HA) is a linear glycosaminoglycan of the vertebrate extracellular matrix that is synthesized at the plasma membrane by the HA synthase (HAS)…”
Get full text

Functional analysis of human promoter polymorphisms by Hoogendoorn, Bastiaan, Coleman, Sharon L., Guy, Carol A., Smith, Kaye, Bowen, Tim, Buckland, Paul R., O'Donovan, Michael C.

“…The potential importance of gene regulation in disease susceptibility and other inherited phenotypes has been underlined by the observation that the human…”
Get full text

Low Gene Expression Conferred by Association of an Allele of the 5-HT2C Receptor Gene With Antipsychotic-Induced Weight Gain by Buckland, Paul R., Hoogendoorn, Bastiaan, Guy, Carol A., Smith, S. Kaye, Coleman, Sharon L., O'Donovan, Michael C.

“…OBJECTIVE: Association has been reported between the C allele of a -759C T polymorphism in the promoter of the 5-HT2C receptor gene (HTR2C) and…”
Get full text

CAG repeat length in the hKCa3 gene and symptom dimensions in schizophrenia by Cardno, Alastair G, Bowen, Timothy, Guy, Carol A, Jones, Lisa A, McCarthy, Geraldine, Williams, Nigel M, Murphy, Kieran C, Spurlock, Gillian, Gray, Marion, Sanders, Robert D, Craddock, Nick, McGuffin, Peter, Owen, Michael J, O’Donovan, Michael C

“…Background: Long CAG repeats in the hKCa3 potassium channel gene have been associated with schizophrenia. We sought evidence for associations between this…”
Get full text

Strong bias in the location of functional promoter polymorphisms by Buckland, Paul R., Hoogendoorn, Bastiaan, Coleman, Sharon L., Guy, Carol A., Smith, S. Kaye, O'Donovan, Michael C.

“…A considerable proportion of heritable human phenotypic variation is thought to result from altered gene expression. Unfortunately, it is currently impossible…”
Get full text

A high proportion of polymorphisms in the promoters of brain expressed genes influences transcriptional activity by Buckland, Paul R., Hoogendoorn, Bastiaan, Guy, Carol A., Coleman, Sharon L., Smith, S. Kaye, Buxbaum, Joseph D., Haroutunian, Vahram, O'Donovan, Michael C.

“…There is increasing interest in the possibility that polymorphisms affecting gene expression are responsible for a significant proportion of heritable human…”
Get full text

Functional analysis of polymorphisms in the promoter regions of genes on 22q11 by Hoogendoorn, Bastiaan, Coleman, Sharon L., Guy, Carol A., Smith, S. Kaye, O'Donovan, Michael C., Buckland, Paul R.

“…Segmental aneusomy, which includes chromosome 22 deletion syndrome (del(22)(q11.2q11.2)), has been associated with DiGeorge syndrome (DGS), velocardiofacial…”
Get full text

The human hyaluronan synthase genes: genomic structures, proximal promoters and polymorphic microsatellite markers by Monslow, Jamie, Williams, John D., Norton, Nadine, Guy, Carol A., Price, Iain K., Coleman, Sharon L., Williams, Nigel M., Buckland, Paul R., Spicer, Andrew P., Topley, Nicholas, Davies, Malcolm, Bowen, Timothy

“…The glycosaminoglycan (GAG) hyaluronan (HA) is a key component of the vertebrate extracellular matrix (ECM) and is synthesised by the HA synthase (HAS) enzymes…”
Get full text

Low Gene Expression Conferred by Association of an Allele of the 5-HT 2C Receptor Gene With Antipsychotic-Induced Weight Gain by Buckland, Paul R., Hoogendoorn, Bastiaan, Guy, Carol A., Smith, S. Kaye, Coleman, Sharon L., O’Donovan, Michael C.

Get full text

No evidence of association from transmission disequilibrium analysis of the hKCa3 gene in bipolar disorder by Bowen, Timothy, Ashworth, Lindsay, Kirov, George, Guy, Carol A, Jones, Ian R, McCandless, Fiona, Craddock, Nick, O'donovan, Michael C, Owen, Michael J

“…Objective: A recent case–control study has suggested that modest enlargements of a highly polymorphic CAG repeat in exon 1 of the gene encoding potassium…”
Get full text

Expanded CAG/CTG repeats in schizophrenia. A study of clinical correlates by Cardno, A G, Murphy, K C, Jones, L A, Guy, C A, Asherson, P, De Azevedo, M H, Coelho, I M, de Macedo e Santos, A J, Pato, C N, McGuffin, P, Owen, M J, O'Donovan, M C

“…Schizophrenia is associated with expanded CAG/CTG trinucleotide repeats. We wished to determine whether the presence of such expansions correlated with…”
Get more information

Promoter polymorphisms in glutathione-S-transferase genes affect transcription by GUY, Carol A, HOOGENDOORN, Bastiaan, SMITH, S. Kaye, COLEMAN, Sharon, O'DONOVAN, Michael C, BUCKLAND, Paul R

“…The glutathione-S-transferases are a group of enzymes that play a major role in detoxification and defence against toxic, carcinogenic and other compounds. We…”
Get full text

Low Gene Expression Conferred by Association of an Allele of the 5-HT sub(2C) Receptor Gene With Antipsychotic-Induced Weight Gain by Buckland, Paul R, Hoogendoorn, Bastiaan, Guy, Carol A, Smith, SKaye, Coleman, Sharon L, O'donovan, Michael C

“…OBJECTIVE: Association has been reported between the C allele of a -759C/T polymorphism in the promoter of the 5-HT sub(2C) receptor gene (HTR2C) and…”
Get full text

Low Gene Expression Conferred by Association of an Allele of the 5-HT^sub 2C^ Receptor Gene With Antipsychotic-Induced Weight Gain by Buckland, Paul R, Hoogendoorn, Bastiaan, Guy, Carol A, S Kaye Smith

“…Association has been reported between the C allele of a -759C/T polymorphism in the promoter of the 5-HT2c receptor gene (HTR2C) and antipsychotic-induced…”
Get full text

Long repeat tracts atSCA8 in major psychosis by Vincent, John B., Yuan, Qiu-Ping, Schalling, Martin, Adolfsson, R, Azevedo, M. Helena, Macedo, Antonio, Bauer, Amy, DallaTorre, Camille, Medeiros, Helena M., Pato, Michele T., Pato, Carlos N., Bowen, Timothy, Guy, Carol A., Owen, Michael J., O'Donovan, Michael C., Paterson, Andrew D., Petronis, Arturas, Kennedy, James L.

Get full text

When your review stinks by Guy, Carol A

Get full text

Long repeat tracts at SCA8 in major psychosis by Vincent, John B., Yuan, Qiu-Ping, Schalling, Martin, Adolfsson, R, Azevedo, M. Helena, Macedo, Antonio, Bauer, Amy, DallaTorre, Camille, Medeiros, Helena M., Pato, Michele T., Pato, Carlos N., Bowen, Timothy, Guy, Carol A., Owen, Michael J., O'Donovan, Michael C., Paterson, Andrew D., Petronis, Arturas, Kennedy, James L.

“…Expansion at a recently identified unstable trinucleotide repeat on chromosome 13q21 has been reported as the molecular cause for spinocerebellar ataxia type 8…”
Get full text

Long repeat tracts at SCA8 in major psychosis: Neuropsychiatric Genetics by VINCENT, John B, YUAN, Qiu-Ping, PATO, Carlos N, BOWEN, Timothy, GUY, Carol A, OWEN, Michael J, O'DONOVAN, Michael C, PATERSON, Andrew D, PETRONIS, Arturas, KENNEDY, James L, SCHALLING, Martin, ADOLFSSON, R, AZEVEDO, M. Helena, MACEDO, Antonio, BAUER, Amy, DALLATORRE, Camille, MEDEIROS, Helena M, PATO, Michele T

Get full text