Search Results - "Guven, Hayrettin"

Inhibition of tumor cell proliferation and motility by fibroblasts is both contact and soluble factor dependent by Alkasalias, Twana, Flaberg, Emilie, Kashuba, Vladimir, Alexeyenko, Andrey, Pavlova, Tatiana, Savchenko, Andrii, Szekely, Laszlo, Klein, George, Guven, Hayrettin

“…Significance Normal microenvironments can restrict cancer development and progression. Inhibition of tumor cell growth and motility by normal fibroblasts is…”
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Decreased decorin expression in the tumor microenvironment by Bozoky, Benedek, Savchenko, Andrii, Guven, Hayrettin, Ponten, Fredrik, Klein, George, Szekely, Laszlo

“…Decorin is a small leucine‐rich proteoglycan, synthesized and deposited by fibroblasts in the stroma where it binds to collagen I. It sequesters several growth…”
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A new method for in vitro expansion of cytotoxic human CD3 −CD56 + natural killer cells by Carlens, Stefan, Gilljam, Mari, Chambers, Benedict J, Aschan, Johan, Guven, Hayrettin, Ljunggren, Hans-Gustaf, Christensson, Birger, Dilber, M.Sirac

“…Adoptive transfer of immunocompetent cells may induce anti-tumor effects in vivo. However, a significant obstacle to the development of successful cellular…”
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RhoA knockout fibroblasts lose tumor-inhibitory capacity in vitro and promote tumor growth in vivo by Alkasalias, Twana, Alexeyenko, Andrey, Hennig, Katharina, Danielsson, Frida, Lebbink, Robert Jan, Fielden, Matthew, Turunen, S. Pauliina, Lehti, Kaisa, Kashuba, Vladimir, Madapura, Harsha S., Bozoky, Benedek, Lundberg, Emma, Balland, Martial, Guvén, Hayrettin, Klein, George, Gad, Annica K. B., Pavlova, Tatiana

“…Fibroblasts are a main player in the tumor-inhibitory microenvironment. Upon tumor initiation and progression, fibroblasts can lose their tumor-inhibitory…”
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Control of cyclooxygenase-2 expression and tumorigenesis by endogenous 5-methoxytryptophan by Cheng, Huei-Hsuan, Kuo, Cheng-Chin, Yan, Jiann-Long, Chen, Hua-Ling, Lin, Wei-Chung, Wang, Kai-Hsuan, Tsai, Kelvin K.-C, Guvén, Hayrettin, Flaberg, Emilie, Szekely, Laszlo, Klein, George, Wu, Kenneth K

“…Cyclooxygenase-2 (COX-2) expression is induced by mitogenic and proinflammatory factors. Its overexpression plays a causal role in inflammation and…”
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The architecture of fibroblast monolayers of different origin differentially influences tumor cell growth by Flaberg, Emilie, Guven, Hayrettin, Savchenko, Andrii, Pavlova, Tatiana, Kashuba, Vladimir, Szekely, Laszlo, Klein, George

“…Normal human and murine fibroblasts can inhibit proliferation of tumor cells when co‐cultured in vitro. The inhibitory capacity varies depending on the donor…”
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Confrontation of fibroblasts with cancer cells in vitro: gene network analysis of transcriptome changes and differential capacity to inhibit tumor growth by Alexeyenko, Andrey, Alkasalias, Twana, Pavlova, Tatiana, Szekely, Laszlo, Kashuba, Vladimir, Rundqvist, Helene, Wiklund, Peter, Egevad, Lars, Csermely, Peter, Korcsmaros, Tamas, Guven, Hayrettin, Klein, George

“…There is growing evidence that emerging malignancies in solid tissues might be kept under control by physical intercellular contacts with normal fibroblasts…”
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Human CD80/IL2 lentivirus‐transduced acute myeloid leukaemia (AML) cells promote natural killer (NK) cell activation and cytolytic activity: implications for a phase I clinical study by Ingram, Wendy, Chan, Lucas, Guven, Hayrettin, Darling, David, Kordasti, Shahram, Hardwick, Nicola, Barber, Linda, Mufti, Ghulam J., Farzaneh, Farzin

“…Summary Immunotherapeutic strategies may promote T and/or natural killer (NK) cell cytotoxicity. NK cells have the potential to exert a powerful anti‐leukaemia…”
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Safety analysis of ex vivo-expanded NK and NK-like T cells administered to cancer patients: a phase I clinical study by Barkholt, Lisbeth, Alici, Evren, Conrad, Reka, Sutlu, Tolga, Gilljam, Mari, Stellan, Birgitta, Christensson, Birger, Guven, Hayrettin, Björkström, Niklas K, Söderdahl, Gunnar, Cederlund, Kerstin, Kimby, Eva, Aschan, Johan, Ringdén, Olle, Ljunggren, Hans-Gustaf, Dilber, M Sirac

“…The chimeric state after allogeneic hematopoietic stem cell transplantation provides a platform for adoptive immunotherapy using donor-derived immune cells…”
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In-Vitro Culture of Human CD80/IL2 Lentivirus Transduced Acute Myeloid Leukemia Cells (AML) Promote NK Cell Activation and Cytolytic Activity by Ingram, Wendy, Chan, Lucas, Guven, Hayrettin, Kordasti, Shahram, Barber, Linda, Hardwick, Nicola, Darling, David, Mufti, Ghulam J, Farzaneh, Farzin

“…Natural killer (NK) cells are increasingly recognized as an important component in the graft versus leukemia response following allogeneic hematopoietic stem…”
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Efficient gene transfer into primary human natural killer cells by retroviral transduction by Guven, Hayrettin, Konstantinidis, Kyriakos V., Alici, Evren, Aints, Alar, Abedi-Valugerdi, Manuchehr, Christensson, Birger, Ljunggren, Hans-Gustaf, Dilber, M. Sirac

“…To optimize retroviral gene transfer into primary human natural killer (NK) cells. NK cells from healthy donors were expanded ex vivo for a period of 21 days…”
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Enhanced ouabain resistance gene as a eukaryotic selection marker by Aints, Alar, Belusa, Roger, Andersson, Ronnie M, Güven, Hayrettin, Dilber, M Sirac

“…Current selection markers allow selection by antibiotics or fluorescent/magnetic sorting by green fluorescent protein or membrane antigens. Antibiotic…”
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