Search Results - "Gutti, Usha"

MicroRNA function in megakaryocytes by Raghuwanshi, Sanjeev, Dahariya, Swati, Musvi, Syed Shahid, Gutti, Usha, Kandi, Ravinder, Undi, Ram Babu, Sahu, Itishri, Gautam, Dushyant Kumar, Paddibhatla, Indira, Gutti, Ravi Kumar

“…Megakaryocytes (MKs), the largest cells in the bone marrow, are generated from hematopoietic stem cells (HSCs) in a sequential process called…”
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MAPK signaling pathways regulate IL-8 mRNA stability and IL-8 protein expression in cystic fibrosis lung epithelial cell lines by Bhattacharyya, Sharmistha, Gutti, Usha, Mercado, Jose, Moore, Chad, Pollard, Harvey B, Biswas, Roopa

“…Cystic fibrosis (CF) is characterized by a massive proinflammatory phenotype in the lung, caused by mutations in the CFTR gene. IL-8 and other proinflammatory…”
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Current Updates on Role of Lipids in Hematopoiesis by Bansal, Priyanka, Dahate, Priyanka, Raghuwanshi, Sanjeev, Sharma, Durga Shankar, Kovuru, Narasaiah, Gutti, Usha, Yarla, Nagendra Sastry, Gutti, RavI Kumar

“…Hematopoiesis is the process which generates all the mature blood cells from the rare pool of Hematopoietic stem cells (HSCs). Asymmetric cell division of HSCs…”
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Apoptosis: role in myeloid cell development by Sarvothaman, Shilpa, Undi, Ram Babu, Pasupuleti, Satya Ratan, Gutti, Usha, Gutti, Ravi Kumar

“…Hematopoiesis is the process that generates blood cells in an organism from the pluripotent stem cells. Hematopoietic stem cells are characterized by their…”
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Tristetraprolin regulates IL-8 mRNA stability in cystic fibrosis lung epithelial cells by Balakathiresan, Nagaraja Sethuraman, Bhattacharyya, Sharmistha, Gutti, Usha, Long, Robert P, Jozwik, Catherine, Huang, Wei, Srivastava, Meera, Pollard, Harvey B, Biswas, Roopa

“…Cystic fibrosis (CF) is due to mutations in the CFTR gene and is characterized by hypersecretion of the proinflammatory chemokine IL-8 into the airway lumen…”
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Elevated miR-155 Promotes Inflammation in Cystic Fibrosis by Driving Hyperexpression of Interleukin-8 by Bhattacharyya, Sharmistha, Balakathiresan, Nagaraja S., Dalgard, Clifton, Gutti, Usha, Armistead, David, Jozwik, Cathy, Srivastava, Meera, Pollard, Harvey B., Biswas, Roopa

“…Cystic Fibrosis (CF) is characterized by a massive proinflammatory phenotype in the lung arising from profound expression of inflammatory genes, including…”
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LiCl regulates mitochondrial biogenesis during megakaryocyte development by Undi, Ram Babu, Gutti, Usha, Gutti, Ravi Kumar

“…•LiCl could activate wnt signaling in megakaryocytes.•LiCl could induce megakaryocyte maturation markers CD41 and CD42.•Increase in mitochondrial biogenesis in…”
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Role of let-7b/Fzd4 axis in mitochondrial biogenesis through wnt signaling: In neonatal and adult megakaryocytes by Undi, Ram Babu, Gutti, Usha, Gutti, Ravi Kumar

“…[Display omitted] •Neonates are susceptible to thrombocytopenia compared to adults for unknown reason.•miRNAs are modulators of healthy as well as abnormal…”
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MicroRNA‐9 promotes cell proliferation by regulating RUNX1 expression in human megakaryocyte development by Raghuwanshi, Sanjeev, Gutti, Usha, Kandi, Ravinder, Gutti, Ravi Kumar

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Justicia adhatoda induces megakaryocyte differentiation through mitochondrial ROS generation by Gutti, Usha, Komati, Jaswant Kumar, Kotipalli, Aneesh, Saladi, Raja Gopal Venakata, Gutti, Ravi Kumar

“…Hepatoprotective activity along with improved survival percentage and hematological parameters prior to whole body irradiation were reported with Justicia…”
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Trans-dominant negative effects of pathogenic PSEN1 mutations on γ-secretase activity and Aβ production by Heilig, Elizabeth A, Gutti, Usha, Tai, Tara, Shen, Jie, Kelleher, 3rd, Raymond J

“…Mutations in the PSEN1 gene encoding Presenilin-1 (PS1) are the predominant cause of familial Alzheimer's disease (FAD), but the underlying mechanisms remain…”
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Micro RNA ‐9 promotes cell proliferation by regulating RUNX 1 expression in human megakaryocyte development by Raghuwanshi, Sanjeev, Gutti, Usha, Kandi, Ravinder, Gutti, Ravi Kumar

“…Specifically, RUNX1 sequence is conserved for miR‐9 among vertebrates and miR‐9 was also identified with decreasing intensity of expression during human MK…”
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Systems biology approach to study the role of miRNA in promoter targeting during megakaryopoiesis by Sahu, Itishri, Hebalkar, Rucha, Kar, Sonika, TS, SreeVidya, Gutti, Usha, Gutti, Ravi Kumar

“…The distinct process of megakaryopoiesis requires occurrence of endomitosis for polyploidization of the megakaryocytes. Although, Cyclins, CDKs and have been…”
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Toll-like receptor 2 signalling: Significance in megakaryocyte development through wnt signalling cross-talk and cytokine induction by Undi, Ram Babu, Sarvothaman, Shilpa, Narasaiah, Kovuru, Gutti, Usha, Gutti, Ravi Kumar

“…•TLR2 induces megakaryocyte maturation and increase cytokine production.•TLR2 is involved in ROS production, which is essential for megakaryocyte…”
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Erythropoietin and thrombopoietin mimetics: Natural alternatives to erythrocyte and platelet disorders by Gutti, Usha, Pasupuleti, Satya Ratan, Sahu, Itishri, Kotipalli, Aneesh, Undi, Ram Babu, Kandi, Ravinder, Venakata Saladi, Raja Gopal, Gutti, Ravi Kumar

“…Highlights • Evolution of EPO and TPO recombinant and synthetic mimetics over the years. • Limitations with current EPO and TPO mimetics. • Current evidence on…”
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Wnt Signaling: Role in Regulation of Haematopoiesis by Undi, Ram Babu, Gutti, Usha, Sahu, Itishri, Sarvothaman, Shilpa, Pasupuleti, Satya Ratan, Kandi, Ravinder, Gutti, Ravi Kumar

“…Hematopoietic stem cells (HSCs) are a unique population of bone marrow cells which are responsible for the generation of various blood cell lineages. One of…”
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Understanding thrombocytopenia: physiological role of microRNA in survival of neonatal megakaryocytes by Kandi, Ravinder, Gutti, Usha, Undi, Rambabu, Sahu, Itishri, Gutti, Ravi Kumar

“…Neonates are predisposed to developing thrombocytopenia and neonates are affected by megakaryocytic disorders such as thrombocytopenia with absent radius…”
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Glucocerebrosidase mutations in Chinese subjects from Taiwan with sporadic Parkinson disease by Ziegler, Shira G., Eblan, Michael J., Gutti, Usha, Hruska, Kathleen S., Stubblefield, Barbara K., Goker-Alpan, Ozlem, LaMarca, Mary E., Sidransky, Ellen

“…An association between glucocerebrosidase, the enzyme deficient in Gaucher disease, and the synucleinopathies has been suggested both by the development of…”
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MiR-125b and miR-99a encoded on chromosome 21 co-regulate vincristine resistance in childhood acute megakaryoblastic leukemia by Kandi, Ravinder, Gutti, Usha, Saladi, Raja Gopal Venakata, Gutti, Ravi Kumar

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Sequence and structural difference favors a distinct preference of Wnt3a binding with co-receptor LRP6 by Sahu, Itishri, Mishra, Seema, Undi, R., Kandi, Ravinder, Gutti, Usha, Gutti, R. K.

“…Wnt signaling pathway plays a key role in a wide array of development and physiological processes. Wnt proteins interact with two different co-receptors LRP5/6…”
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