Search Results - "Guttha, Samyuktha"

GLP-1 Receptor Agonist NLY01 Reduces Retinal Inflammation and Neuron Death Secondary to Ocular Hypertension by Sterling, Jacob K., Adetunji, Modupe O., Guttha, Samyuktha, Bargoud, Albert R., Uyhazi, Katherine E., Ross, Ahmara G., Dunaief, Joshua L., Cui, Qi N.

“…Glaucoma is the leading cause of irreversible blindness and is characterized by the death of retinal ganglion cells (RGCs). Recent studies have implicated…”
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Iron importers Zip8 and Zip14 are expressed in retina and regulated by retinal iron levels by Sterling, Jacob, Guttha, Samyuktha, Song, Ying, Song, Delu, Hadziahmetovic, Majda, Dunaief, Joshua L.

“…Intracellular retinal iron accumulation has been implicated in the pathogenesis of age-related macular degeneration (AMD), the leading cause of irreversible…”
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Inflammatory adipose activates a nutritional immunity pathway leading to retinal dysfunction by Sterling, Jacob K., Baumann, Bailey, Foshe, Sierra, Voigt, Andrew, Guttha, Samyuktha, Alnemri, Ahab, McCright, Sam J., Li, Mingyao, Zauhar, Randy J., Montezuma, Sandra R., Kapphahn, Rebecca J., Chavali, Venkata R.M., Hill, David A., Ferrington, Deborah A., Stambolian, Dwight, Mullins, Robert F., Merrick, David, Dunaief, Joshua L.

“…Age-related macular degeneration (AMD), the leading cause of irreversible blindness among Americans over 50, is characterized by dysfunction and death of…”
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Novel severe oculocutaneous manifestations of human monkeypox virus infection and their historical analogues by Carrubba, Steven, Geevarghese, Alexi, Solli, Elena, Guttha, Samyuktha, Sims, Jeffrey, Sperber, Laurence, Meehan, Shane, Ostrovsky, Ann

“…WHO has declared human mpox (formerly known as monkeypox) a global public health emergency since July, 2022. When case numbers were increasing, so did…”
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A Rare Case of Uremic Optic Neuropathy Without Optic Disc Edema and With a Unique Imaging Correlate: Bilateral Diffusion Restriction of the Optic Nerves by Greenberg, Julia H, Guttha, Samyuktha, Pullano, Alyssa, Warren, Floyd A

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Conditional knockout of hephaestin in the neural retina disrupts retinal iron homeostasis by Zhang, Kevin R., Baumann, Bailey, Song, Ying, Sterling, Jacob, Erler, Elizabeth A., Guttha, Samyuktha, Kozmik, Zbynek, Dunaief, Joshua L.

“…Iron accumulation has been implicated in degenerative retinal diseases. It can catalyze the production of damaging reactive oxygen species. Previous work has…”
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Differential Rates of Toxicity Between Chloroquine and Hydroxychloroquine by Guttha, Samyuktha, Choi, Stephanie, Dedania, Vaidehi S., Mehta, Nitish, Belmont, H. Michael, Modi, Yasha S.

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Interleukin-6 triggers toxic neuronal iron sequestration in response to pathological α-synuclein by Sterling, Jacob K., Kam, Tae-In, Guttha, Samyuktha, Park, Hyejin, Baumann, Bailey, Mehrabani-Tabari, Amir A., Schultz, Hannah, Anderson, Brandon, Alnemri, Ahab, Chou, Shih-Ching, Troncoso, Juan C., Dawson, Valina L., Dawson, Ted M., Dunaief, Joshua L.

“…α-synuclein (α-syn) aggregation and accumulation drive neurodegeneration in Parkinson's disease (PD). The substantia nigra of patients with PD contains excess…”
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