Search Results - "Guttery, D S"

Detection of HER2 amplification in circulating free DNA in patients with breast cancer by Page, K, Hava, N, Ward, B, Brown, J, Guttery, D S, Ruangpratheep, C, Blighe, K, Sharma, A, Walker, R A, Coombes, R C, Shaw, J A

“…Background: Human epidermal growth factor receptor 2 ( HER2 ) is amplified and overexpressed in 20–25% of breast cancers. This study investigated circulating…”
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The presence of disseminated tumour cells in the bone marrow is inversely related to circulating free DNA in plasma in breast cancer dormancy by Payne, R E, Hava, N L, Page, K, Blighe, K, Ward, B, Slade, M, Brown, J, Guttery, D S, Zaidi, S A A, Stebbing, J, Jacob, J, Yagüe, E, Shaw, J A, Coombes, R C

“…Background: The aim of this study was to gain insight into breast cancer dormancy by examining different measures of minimal residual disease (MRD) over time…”
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Innovative Follow-up Strategies for Endometrial Cancer by Collins, A., Taylor, A., Guttery, D.S., Moss, E.L.

“…Increasing recognition of the heterogeneous nature of endometrial cancer, the excellent prognosis of low-risk cases and improvements in risk stratification…”
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Prevalence of ctDNA in early screen-detected breast cancers using highly sensitive and specific dual molecular barcoded personalised mutation assays by Page, K., Martinson, L.J., Hastings, R.K., Fernandez-Garcia, D., Gleason, K.L.T., Gray, M.C., Rushton, A.J., Goddard, K., Guttery, D.S., Stebbing, J., Coombes, R.C., Shaw, J.A.

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NEOCENT: a randomised feasibility and translational study comparing neoadjuvant endocrine therapy with chemotherapy in ER-rich postmenopausal primary breast cancer by Palmieri, C., Cleator, S., Kilburn, L. S., Kim, S. B., Ahn, S.-H., Beresford, M., Gong, G., Mansi, J., Mallon, E., Reed, S., Mousa, K., Fallowfield, L., Cheang, M., Morden, J., Page, K., Guttery, D. S., Rghebi, B., Primrose, L., Shaw, J. A., Thompson, A. M., Bliss, J. M., Coombes, R. C.

“…Neoadjuvant endocrine therapy is an alternative to chemotherapy for women with oestrogen receptor (ER)-positive early breast cancer (BC). We aimed to assess…”
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Longitudinal whole-exome sequencing of cell-free DNA for tracking the co-evolutionary tumor and immune evasion dynamics: longitudinal data from a single patient by Hastings, R.K., Openshaw, M.R., Vazquez, M., Moreno-Cardenas, A.B., Fernandez-Garcia, D., Martinson, L., Kulbicki, K., Primrose, L., Guttery, D.S., Page, K., Toghill, B., Richards, C., Thomas, A., Tabernero, J., Coombes, R.C., Ahmed, S., Toledo, R.A., Shaw, J.A.

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Abstract P4-01-02: Early detection of residual breast cancer through a robust, scalable and personalized analysis of circulating tumour DNA (ctDNA) antedates overt metastatic recurrence by Coombes, RC, Armstrong, A, Ahmed, S, Page, K, Hastings, RK, Salari, R, Sethi, H, Boydell, A-R, Shchegrova, SV, Fernandez-Garcia, D, Gleason, KL, Goddard, K, Guttery, DS, Assaf, ZJ, Balcioglu, M, Moore, DA, Primrose, L, Navarro, SL, Aleshin, A, Rehman, F, Toghill, BJ, Louie, MC, Zimmermann, BG, Lin, C-HJ, Shaw, JA

“…Abstract Background: Many breast cancer patients relapse after primary treatment but there are no reliable tests to detect distant metastases before they…”
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