Search Results - "Guttendorf, Robert J"

A phase 1b randomized clinical trial of CT1812 to measure Aβ oligomer displacement in Alzheimer's disease using an indwelling CSF catheter by LaBarbera, Kelsie M, Sheline, Yvette I, Izzo, Nicholas J, Yuede, Carla M, Waybright, Lora, Yurko, Raymond, Edwards, Hannah M, Gardiner, Woodrow D, Blennow, Kaj, Zetterberg, Henrik, Börjesson-Hanson, Anne, Morgan, Roger, Davis, Charles S, Guttendorf, Robert J, Schneider, Lon S, DeKosky, Steven, LeVine, 3rd, Harry, Grundman, Michael, Caggiano, Anthony O, Cirrito, John R, Catalano, Susan M, Hamby, Mary E

“…In support of this, Aβ oligomer reduction in an AD mouse model leads to memory preservation [2, 3], and clinical benefit was in trials of lecanemab, which…”
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Percutaneous Hepatic Perfusion With Filtered Melphalan for Localized Treatment of Metastatic Hepatic Disease: A Risk Assessment by McEwan, Pauline E., Bailey, Lynn, Trost, David, Scull, Christopher, Keating, John H., Williams, Misty, Guttendorf, Robert J.

“…Regional therapies for metastatic liver disease have garnered interest in recent years due to technological advances in drug delivery. A percutaneous hepatic…”
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Effects of Organic Anion, Organic Cation, and Dipeptide Transport Inhibitors on Cefdinir in the Isolated Perfused Rat Kidney by LEPSY, Christopher S, GUTTENDORF, Robert J, KUGLER, Alan R, SMITH, David E

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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A Pharmacokinetic and Bioavailability Study of Ecklonia cava Phlorotannins Following Intravenous and Oral Administration in Sprague–Dawley Rats by Shin, Hyeon-Cheol, Rosenfeld, Clint, Guttendorf, Robert J., Wade, Susan B., Park, Yong Ju, Kim, Ju Hee, Kim, Seong Ho, Lee, Bong Ho, Hwang, Hye Jeong

“…This study examines the pharmacokinetics and bioavailability of phlorotannins from Ecklonia cava in rats following intravenous and oral administration. Known…”
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HIV Protease Inhibitors Possessing a Novel, High-Affinity, and Achiral P1'/P2' Ligand with a Unique Pattern of in Vitro Resistance. Importance of a Conformationally-Restricted Template in the Design of Enzyme Inhibitors by Prasad, J. V. N. Vara, Lunney, Elizabeth A, Ferguson, Donna, Tummino, Peter J, Rubin, J. Ronald, Reyner, Eric L, Stewart, Barbra H, Guttendorf, Robert J, Domagala, John M

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Pharmacokinetics of Clinafloxacin Enantiomers in Humans by Humphrey, Gaye H., Shapiro, Martin A., Randinitis, Edward J., Guttendorf, Robert J., Brodfuehrer, Joanne I.

“…The pharmacokinetics of R‐clinafloxacin and S‐clinafloxacin enantiomers of the broad‐spectrum fluoroquinolone antibiotic, clinafloxacin, were characterized in…”
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Genetic aspects of drug disposition and therapeutics by Guttendorf, R J, Wedlund, P J

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Nonpeptidic HIV protease inhibitors: 4-hydroxy-pyran-2-one inhibitors with functional tethers to P1 phenyl ring to reach S3 pocket of the enzyme by Vara Prasad, J, Tummino, P J, Ferguson, D, Saunders, J, Vander Roest, S, McQuade, T J, Heldsinger, A, Reyner, E L, Stewart, B H, Guttendorf, R J, Para, K S, Lunney, E A, Gracheck, S J, Domagala, J M

“…A systematic study of tethering various groups on 6-phenyl ring of 4-hydroxy-6-phenyl-3-[(2-isopropylphenyl)thio]pyran-2-one was performed to increase the…”
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Nonpeptidic HIV Protease Inhibitors: 4-Hydroxy-pyran-2-one Inhibitors with Functional Tethers to P1Phenyl Ring to Reach S3Pocket of the Enzyme by Vara Prasad, J.V.N., Tummino, Peter J., Ferguson, Donna, Saunders, James, Vander Roest, Steve, McQuade, Thomas J., Heldsinger, Andrea, Reyner, Eric L., Stewart, Barbra H., Guttendorf, Robert J., Para, Kimberly S., Lunney, Elizabeth A., Gracheck, Stephen J., Domagala, John M.

“…A systematic study of tethering various groups on 6-phenyl ring of 4-hydroxy-6-phenyl-3-[(2-iso-propylphenyl)thio]pyran-2-one was performed to increase the…”
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Simplified phenotyping with dextromethorphan by thin-layer chromatography: application to clinical laboratory screening for deficiencies in oxidative drug metabolism by Guttendorf, R J, Wedlund, P J, Blake, J, Chang, S L

“…Identifying individuals with a deficient capacity for oxidative drug metabolism is of increasing clinical importance. Dextromethorphan (DM) is gaining wide…”
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High-performance liquid chromatographic assay for CI-1004, a dual-inhibitor antiinflammatory agent, in rat, rabbit, dog, monkey and human plasma by Andress, Larry D., Guttendorf, Robert J.

“…CI-1004 and PD 138389 (internal standard, I.S.), were isolated from rat, rabbit, dog, monkey and human plasma by solid-phase extraction with Bond-Elut C18…”
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Quantification of propranolol enantiomers in small blood samples from rats by reversed-phase high-performance liquid chromatography after chiral derivatization by Guttendorf, R J, Kostenbauder, H B, Wedlund, P J

“…A high-performance liquid chromatographic (HPLC) technique is described for quantification of R(+)- and S(-)-propranolol from 100-microliters rat blood…”
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