Search Results - "Gutkin, Dmitriy W."
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Clinical evaluation of systemic and local immune responses in cancer: time for integration
Published in Cancer Immunology, Immunotherapy (01-01-2014)“…The immune system has a dual role in cancer development and progression. On the one hand, it can eradicate emerging malignant cells, but on the other hand, it…”
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Tumor associated regulatory dendritic cells
Published in Seminars in cancer biology (01-08-2012)“…Abstract Immune effector and regulatory cells in the tumor microenvironment are key factors in tumor development and progression as the pathogenesis of cancer…”
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Carbon Nanotubes Enhance Metastatic Growth of Lung Carcinoma via Up-Regulation of Myeloid-Derived Suppressor Cells
Published in Small (Weinheim an der Bergstrasse, Germany) (27-05-2013)“…Metastatic establishment and growth of Lewis lung carcinoma is promoted by single‐walled carbon nanotubes (SWCNT) in C57BL6/J mice. The effect is mediated by…”
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Sensitization of pelvic nerve afferents and mast cell infiltration in the urinary bladder following chronic colonic irritation is mediated by neuropeptides
Published in American journal of physiology. Renal physiology (01-01-2007)“…Irritable bowel syndrome and interstitial cystitis frequently overlap. We have shown that acute colitis sensitizes urinary bladder afferents to both mechanical…”
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Mediation of the single-walled carbon nanotubes induced pulmonary fibrogenic response by osteopontin and TGF-β1
Published in Experimental lung research (14-09-2017)“…Purpose of the study: A number of in vivo studies have shown that pulmonary exposure to carbon nanotubes (CNTs) may lead to an acute local inflammatory…”
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The role of TLR4 in the paclitaxel effects on neuronal growth in vitro
Published in PloS one (18-02-2013)“…Paclitaxel (Pac) is an antitumor agent that is widely used for treatment of solid cancers. While being effective as a chemotherapeutic agent, Pac in high doses…”
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Epigenetic Mechanisms of Promigratory Chemokine CXCL14 Regulation in Human Prostate Cancer Cells
Published in Cancer research (Chicago, Ill.) (01-06-2010)“…Chemokines play the key role in initiating immune responses by regulating the attraction and homing of immune cells to the lymphoid and nonlymphoid tissues…”
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Gender differences in murine pulmonary responses elicited by cellulose nanocrystals
Published in Particle and fibre toxicology (08-06-2016)“…Cellulose-based materials have been used for centuries to manufacture different goods derived from forestry and agricultural sources. In the growing field of…”
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MDSC and TGFβ Are Required for Facilitation of Tumor Growth in the Lungs of Mice Exposed to Carbon Nanotubes
Published in Cancer research (Chicago, Ill.) (15-04-2015)“…During the last decades, changes have been observed in the frequency of different histologic subtypes of lung cancer, one of the most common causes of…”
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Origin and pharmacological modulation of tumor‐associated regulatory dendritic cells
Published in International journal of cancer (01-06-2014)“…Protumorigenic activity of immune regulatory cells has been proven to play a major role in precluding immunosurveillance and limiting the efficacy of…”
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Characterization of pulmonary responses in mice to asbestos/asbestiform fibers using gene expression profiles
Published in Journal of Toxicology and Environmental Health, Part A (01-01-2018)“…Humans exposed to asbestos and/or asbestiform fibers are at high risk of developing many lung diseases including asbestosis, lung cancer, and malignant…”
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Pulmonary exposure to cellulose nanocrystals caused deleterious effects to reproductive system in male mice
Published in Journal of Toxicology and Environmental Health, Part A (01-01-2016)“…Over the past several years there has been an increased number of applications of cellulosic materials in many sectors, including the food industry, cosmetics,…”
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Enhanced expression of mast cell growth factor and mast cell activation in the bladder following the resolution of trinitrobenzenesulfonic acid (TNBS) colitis in female rats
Published in Neurourology and urodynamics (01-01-2007)“…Aims Chronic pelvic pain disorders often overlap. We have shown that acute colonic irritation can produce acute irritative micturition patterns and acutely…”
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Biodiesel versus diesel exposure: Enhanced pulmonary inflammation, oxidative stress, and differential morphological changes in the mouse lung
Published in Toxicology and applied pharmacology (15-10-2013)“…The use of biodiesel (BD) or its blends with petroleum diesel (D) is considered to be a viable approach to reduce occupational and environmental exposures to…”
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Abnormalities in the male reproductive system after exposure to diesel and biodiesel blend
Published in Environmental and molecular mutagenesis (01-03-2015)“…Altering the fuel source from petroleum‐based ultralow sulfur diesel to biodiesel and its blends is considered by many to be a sustainable choice for…”
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54 Mast Cells Play a Pivotal Role in the Development of Pelvic Organ Chronic Sensitization
Published in Gastroenterology (New York, N.Y. 1943) (2008)Get full text
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Abstract 3375: Can prostate cancer derived neuromodulators regulate intratumoral axonogenesis
Published in Cancer research (Chicago, Ill.) (01-08-2015)“…Abstract Well-developed angiolymphatic network in solid malignant tumors has been proven as an important requirement for tumor growth and progression. However,…”
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Isolation of an Alu repetitive DNA binding protein and effect of CpG methylation on binding to its recognition sequence
Published in Biochimica et biophysica acta (04-03-1998)“…The structure, expression, and evolution of Alu repetitive DNA elements have been extensively studied, but the role of these sequences in the function of…”
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