Search Results - "Gutjahr, Ulrike"
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1
Characterization and chemical modification of the Na(+)-dependent bile-acid transport system in brush-border membrane vesicles from rabbit ileum
Published in Biochimica et biophysica acta (19-10-1992)“…The Na(+)-dependent uptake system for bile acids in the ileum from rabbit small intestine was characterized using brush-border membrane vesicles. The uptake of…”
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2
Intestinal bile acid absorption. Na(+)-dependent bile acid transport activity in rabbit small intestine correlates with the coexpression of an integral 93-kDa and a peripheral 14-kDa bile acid-binding membrane protein along the duodenum-ileum axis
Published in The Journal of biological chemistry (25-08-1993)“…The anatomical localization of the Na+/bile acid cotransport system from rabbit small intestine was determined using brush border membrane vesicles prepared…”
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Journal Article -
3
Liver-specific drug targeting by coupling to bile acids
Published in The Journal of biological chemistry (15-09-1992)“…Bile acids are selectively taken up from portal blood into the liver by specific transport systems in the hepatocyte plasma membrane. Therefore, studies were…”
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4
Intestinal absorption of peptides by coupling to bile acids
Published in The Journal of biological chemistry (08-04-1994)“…Poor intestinal absorption of peptides greatly limits their use as drugs for the treatment of chronic diseases. Since bile acids are efficiently absorbed by an…”
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Journal Article -
5
Interaction of renin inhibitors with the intestinal uptake system for oligopeptides and beta-lactam antibiotics
Published in Biochimica et biophysica acta (10-08-1990)“…The interaction of two renin inhibitors, S 86,2033 and S 86,3390, with the uptake system for beta-lactam antibiotics and small peptides in the brush border…”
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6
Interaction of the orally active dianionic cephalosporin cefixime with the uptake system for oligopeptides and alpha-amino-beta-lactam antibiotics in rabbit small intestine
Published in Biochemical pharmacology (03-08-1993)“…The uptake of two orally active beta-lactam antibiotics of different chemical structure, the zwitterionic alpha-aminocephalosporin cephalexin and the dianionic…”
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7
The molecular interaction of sulfonylureas with β-cell ATP-sensitive K +-channels
Published in Diabetes research and clinical practice (01-08-1995)“…The molecular interaction of glimepiride and glibenclamide with the β-cell sulfonylurea receptor was investigated by kinetic and steady state binding as well…”
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Journal Article Conference Proceeding -
8
Influence of amino acid side-chain modification on the uptake system for beta-lactam antibiotics and dipeptides from rabbit small intestine
Published in Biochimica et biophysica acta (05-10-1990)“…The influence of chemical modification of functional amino acid side-chains in proteins on the H(+)-dependent uptake system for orally active…”
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9
Intestinal absorption of β-lactam antibiotics and oligopeptides : functional and stereospecific reconstitution of the oligopeptide transport system from rabbit small intestine
Published in European journal of biochemistry (01-03-1992)“…The H(+)-dependent uptake system responsible for the enteral absorption of oligopeptides and orally active beta-lactam antibiotics was functionally…”
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Journal Article -
10
Intestinal absorption of β‐lactam antibiotics and oligopeptides
Published in European journal of biochemistry (01-03-1992)“…The H+‐dependent uptake system responsible for the enteral absorption of oligopeptides and orally active β‐lactam antibiotics was functionally reconstituted…”
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