Search Results - "Gutierrez Nicolás, Fernando"
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Definition of a therapeutic range for predicting long-term infliximab response in patients with inflammatory bowel disease
Published in Medicina clinica (10-02-2023)“…Monitoring plasma levels of Infliximab plays an important role in optimising treatment in patients with inflammatory bowel disease (IBD). The aim of the…”
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Allelic Frequency of DPYD Genetic Variants in Patients With Cancer in Spain: The PhotoDPYD Study
Published in The oncologist (Dayton, Ohio) (01-05-2023)“…Abstract Introduction Identifying polymorphisms in the dihydropyrimidine dehydrogenase (DPYD) gene is gaining importance to be able to predict…”
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Anti-drug antibodies anti-trastuzumab in the treatment of breast cancer
Published in Journal of oncology pharmacy practice (01-08-2021)“…Introduction Trastuzumab is a monoclonal antibody which could induce the activation of a humoral immune response generating anti-drug antibodies (ADAs). Such…”
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Assessment of exposure-response relationship for bevacizumab in patients with metastatic colorectal cancer
Published in Biomedicine & pharmacotherapy (01-09-2021)“…Limited literature is available for bevacizumab exposure-response relationship and there is not a concentration threshold associated with an optimal disease…”
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Risk factors determining adherence to tyrosine kinase inhibitors in chronic myeloid leukaemia
Published in Journal of oncology pharmacy practice (01-08-2024)“…Objective Tyrosine kinase inhibitors (TKIs) have successfully changed the natural course of chronic myeloid leukaemia (CML). Although they are highly effective…”
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Imatinib plasma levels in patients with gastrointestinal stromal tumour under routine clinical practice conditions
Published in Journal of oncology pharmacy practice (01-10-2023)“…Objectives Imatinib is the first therapeutic option for the treatment of unresectable or metastatic gastrointestinal stromal tumours. Previous studies have…”
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Imatinib plasma levels in patients with chronic myeloid leukaemia under routine clinical practice conditions
Published in Journal of oncology pharmacy practice (01-01-2023)“…Introduction The addition of imatinib to the therapeutic arsenal for chronic myeloid leukaemia (CML) has changed the natural course of the disease, in such a…”
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Pharmacist-led medication reconciliation to reduce discrepancies in transitions of care in Spain
Published in International journal of clinical pharmacy (01-12-2013)“…Background Medication errors are one of the main causes of morbidity amongst hospital inpatients. More than half of medication errors occur at ‘interfaces of…”
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Ten-minute administration of bevacizumab
Published in European journal of hospital pharmacy. Science and practice (01-07-2019)“…ObjectiveTo describe our experience of administering bevacizumab doses at 0.5 mg/kg/min. The main objective of the study was to evaluate the safety of this…”
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Cost-effectiveness of pemetrexed in combination with cisplatin as first line treatment for patients with advanced non-squamous non-small-cell lung cancer in Spain
Published in Farmacia hospitalaria (01-01-2017)“…Lung cancer is the third most frequent neoplastic tumour in Spain, with around 27 000 new cases diagnosed per year; 80-95% of these are non-small-cell cancer…”
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11
Reducing the degree of colonisation of venous access catheters by continuous passive disinfection
Published in European journal of hospital pharmacy. Science and practice (01-05-2016)“…IntroductionThe advent of Luer-type needleless venous access catheters has been accompanied by a growing number of catheter-related bloodstream infections. Our…”
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Efficacy and Safety of Erenumab, Galcanezumab, and Fremanezumab in the Treatment of Drug-Resistant Chronic Migraine: Experience in Real Clinical Practice
Published in The Annals of pharmacotherapy (01-04-2023)“…Background: Due to the recent introduction of new biologic drugs for chronic migraine, a global evaluation in real clinical practice is necessary. Objective:…”
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Efficacy and safety of high doses of irinotecan in patients with metastatic colorectal cancer treated with the FOLFIRI regimen based on the UGT1A1 genotype: A systematic review
Published in Farmacia hospitalaria (01-07-2022)“…The purpose of this systematic review is to analyze the published data on the efficacy and safety of doses higher than 180 mg/m2 of irinotecan recommended in…”
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Effect of Concomitant Use of Proton Pump Inhibitors on Immunotherapy Clinical Response in Advanced Cancer Patients: Real-Life Setting
Published in Journal of immunotherapy (1997) (01-01-2024)“…The alteration of the gut microbiota mediated by proton pump inhibitor (PPI) drugs could be involved in the clinical response associated with immunotherapy…”
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Activity of Erwinia-asparaginase after anaphylactic reaction to Peg-asparaginase
Published in Anales de Pediatría (01-03-2019)Get full text
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Pharmacokinetics of Trastuzumab After Subcutaneous and Intravenous Administration in Obese Patients
Published in The Annals of pharmacotherapy (01-08-2020)“…Background: Subcutaneous trastuzumab (T-SC) administration does not allow the historical target concentration of 20 µg/mL for efficacy to be reached, from the…”
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Influence of Anthropometric Characteristics in Patients With Her2-Positive Breast Cancer on Initial Plasma Concentrations of Trastuzumab
Published in The Annals of pharmacotherapy (01-11-2017)“…Background: Plasma concentrations of trastuzumab <20 µg/mL in patients with gastric cancer are associated with reduced progression-free and overall survival…”
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A slowdown of hepatitis C diagnosis in high-prevalence groups and with decentralized diagnostic strategies during the COVID-19 pandemic
Published in Revista española de enfermedades digestivas (01-04-2023)“…the COVID-19 pandemic has had a major impact on hepatitis C virus (HCV) diagnosis by hindering the path to elimination. Albeit, in an uneven manner, depending…”
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Adherence to subcutaneous biologic treatment for inflammatory bowel disease
Published in Gastroenterología y hepatología (01-05-2022)“…Nonadherence to medication is common in patients with inflammatory bowel disease (IBD) and can result in disease complications, therapy escalation, and the…”
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Extended enzymatic stability of reconstituted lyophilized PEG-asparaginase in vials
Published in Journal of oncology pharmacy practice (01-07-2021)“…Asparaginase (ASNase) use as a tumour-inhibitor drug has changed completely the natural course of paediatric acute lymphoblastic leukaemia (ALL) in such a way…”
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