Search Results - "Gutierrez‐Barrera, Angelica M."
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Inflammatory breast cancer: a proposed conceptual shift in the UICC–AJCC TNM staging system
Published in The lancet oncology (01-04-2017)“…Summary In the absence of histological criteria that distinguish between inflammatory and non-inflammatory breast cancer, diagnosis of inflammatory breast…”
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Response to Neoadjuvant Systemic Therapy for Breast Cancer in BRCA Mutation Carriers and Noncarriers: A Single-Institution Experience
Published in Journal of clinical oncology (01-10-2011)“…To compare the pathologic complete response (pCR) rate and relapse-free survival (RFS) and overall survival (OS) after neoadjuvant systemic chemotherapy (NST)…”
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Simplifying clinical use of the genetic risk prediction model BRCAPRO
Published in Breast cancer research and treatment (01-06-2013)“…Health care providers need simple tools to identify patients at genetic risk of breast and ovarian cancers. Genetic risk prediction models such as BRCAPRO…”
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Clinical outcomes and Oncotype DX Breast Recurrence Score® in early‐stage BRCA‐associated hormone receptor‐positive breast cancer
Published in Cancer medicine (Malden, MA) (01-03-2022)“…Background BRCA‐associated breast cancers tend to have distinctive features compared to sporadic breast cancers; further characterization can aid in optimizing…”
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Association between weight gain during adjuvant chemotherapy for early‐stage breast cancer and survival outcomes
Published in Cancer medicine (Malden, MA) (01-11-2017)“…Obese and overweight women have an increased risk of breast cancer and worse outcomes at the time of diagnosis. Women tend to gain weight after breast cancer…”
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Contralateral Risk-Reducing Mastectomy in Breast Cancer Patients Who Undergo Multigene Panel Testing
Published in Annals of surgical oncology (01-11-2020)“…Background An increasing number of breast cancer patients are undergoing expanded genetic testing and are being identified as germline mutation carriers. We…”
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Assessing the added value of breast tumor markers in genetic risk prediction model BRCAPRO
Published in Breast cancer research and treatment (01-05-2012)“…The BRCAPRO model estimates carrier probabilities for the BRCA1 and BRCA2 genes, and was recently enhanced to use estrogen receptor (ER) and progesterone…”
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The PARP inhibitor AZD2281 (Olaparib) induces autophagy/mitophagy in BRCA1 and BRCA2 mutant breast cancer cells
Published in International journal of oncology (01-07-2015)“…PARP inhibitors are considered promising anti-cancer agents and currently being tested in clinical trials in hereditary breast cancer patients harboring…”
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Other Primary Malignancies in Patients with Breast Cancer Who Undergo Germline Panel Testing
Published in Annals of surgical oncology (01-03-2023)“…Background Women with a history of breast cancer (BC) more commonly have a diagnosis of other primary malignancies (OPMs) than the general population. This…”
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Evaluation of BRCAPRO Risk Assessment Model in Patients with Ductal Carcinoma In situ Who Underwent Clinical BRCA Genetic Testing
Published in Frontiers in genetics (27-04-2016)“…The authors retrospectively aimed to determine which of the following three scenarios, related to DCIS entry into BRCAPRO, predicted BRCA mutation status more…”
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Early onset HER2‐positive breast cancer is associated with germline TP53 mutations
Published in Cancer (15-02-2012)“…BACKGROUND: Germline TP53 mutations predispose to early onset breast cancer in women and are associated with Li‐Fraumeni syndrome. Published data on the…”
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Cytoplasmic Cyclin E Expression Predicts for Response to Neoadjuvant Chemotherapy in Breast Cancer
Published in Annals of surgery (01-08-2021)“…BACKGROUND:Pathologic complete response (pCR) has been shown to be associated with favorable outcomes in breast cancer. Predictors of pCR could be useful in…”
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Contralateral Prophylactic Mastectomy among Women with Pathogenic Variants in BRCA1/2: Overall Survival, Racial, and Ethnic Differences
Published in The breast journal (2022)“…Background. Patients with unilateral breast cancer carrying pathogenic variants in BRCA1/2 have the option to undergo contralateral prophylactic mastectomy…”
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Expanding the Criteria for BRCA Mutation Testing in Breast Cancer Survivors
Published in Journal of clinical oncology (20-09-2010)“…Every year approximately 25% of women diagnosed with breast cancer are younger than 50 years of age, and almost 10% of them have a BRCA mutation. Not all…”
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High incidence of germline BRCA mutation in patients with ER low‐positive/PR low‐positive/HER‐2 neu negative tumors
Published in Cancer (01-10-2015)“…BACKGROUND The 2015 National Comprehensive Cancer Network guidelines recommend that genetic counseling and germline BRCA mutation testing be offered to women…”
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Elevated serum levels of sialyl Lewis X (sLeX) and inflammatory mediators in patients with breast cancer
Published in Breast cancer research and treatment (01-08-2019)“…Purpose The carbohydrate sialyl Lewis X (sLe X ) mediates cell adhesion, is critical in the normal function of immune cells, and is frequently over-expressed…”
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Clinical outcome and toxicity from taxanes in breast cancer patients with BRCA1 and BRCA2 pathogenic germline mutations
Published in The breast journal (01-08-2020)“…Germline variations in genes coding for proteins involved in the oxidative stress and DNA repair greatly influence drug response and toxicity. Because BRCA1…”
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Reply to Diagnosis of patients with inflammatory breast cancer is a problematic issue
Published in Cancer (15-02-2018)Get full text
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BRCA mutations in women with inflammatory breast cancer
Published in Cancer (01-02-2018)“…BACKGROUND Inflammatory breast cancer (IBC) often affects women at a relatively young age. To the authors' knowledge, the rate of BRCA variants among patients…”
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Incidence and impact of brain metastasis in patients with hereditary BRCA1 or BRCA2 mutated invasive breast cancer
Published in NPJ breast cancer (07-04-2022)“…Patients with hereditary mutations in BRCA1 or BRCA2 (gBRCA1/2) and breast cancer have distinct tumor biology, and encompass a predilection for brain…”
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