Search Results - "Gutierrez, Gloria E"

Using a Consensus Docking Approach to Predict Adverse Drug Reactions in Combination Drug Therapies for Gulf War Illness by Jaundoo, Rajeev, Bohmann, Jonathan, Gutierrez, Gloria E, Klimas, Nancy, Broderick, Gordon, Craddock, Travis J A

“…Gulf War Illness (GWI) is a chronic multisymptom illness characterized by fatigue, musculoskeletal pain, and gastrointestinal and cognitive dysfunction…”
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Quantitative measures of femoral fracture repair in rats derived by micro-computed tomography by Nyman, Jeffry S, Munoz, Steve, Jadhav, Satyawan, Mansour, Alfred, Yoshii, Toshitaka, Mundy, Gregory R, Gutierrez, Gloria E

“…Abstract Although fracture healing is frequently studied in pre-clinical models of long bone fractures using rodents, there is a dearth of objective…”
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Transdermal Lovastatin Enhances Fracture Repair in Rats by Gutierrez, Gloria E, Edwards, James R, Garrett, Ian R, Nyman, Jeffry S, McCluskey, Brandon, Rossini, Gianni, Flores, Alda, Neidre, Daria B, Mundy, Gregory R

“…Statins have been shown to stimulate BMP2 transcription and bone formation. This raises the possibility that they could be useful for enhancing rates of…”
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A sustained release of lovastatin from biodegradable, elastomeric polyurethane scaffolds for enhanced bone regeneration by Yoshii, Toshitaka, Hafeman, Andrea E, Nyman, Jeffry S, Esparza, Javier M, Shinomiya, Kenichi, Spengler, Dan M, Mundy, Gregory R, Gutierrez, Gloria E, Guelcher, Scott A

“…Scaffolds prepared from biodegradable polyurethanes (PUR) have been investigated as a supportive matrix and delivery system for skin, cardiovascular, and bone…”
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The ω‐3 fatty acid α‐linolenic acid extends Caenorhabditis elegans lifespan via NHR‐49/PPARα and oxidation to oxylipins by Qi, Wenbo, Gutierrez, Gloria E., Gao, Xiaoli, Dixon, Hong, McDonough, Joe A., Marini, Ann M., Fisher, Alfred L.

“…Summary The dietary intake of ω‐3 polyunsaturated fatty acids has been linked to a reduction in the incidence of aging‐associated disease including…”
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The polyphenol resveratrol promotes skeletal growth in mice through a sirtuin 1‐bone morphogenic protein 2 longevity axis by Zhao, Ming, Ko, Seon‐Yle, Garrett, I Ross, Mundy, Gregory R, Gutierrez, Gloria E, Edwards, James R

“…Background and Purpose The polyphenol resveratrol (RSV) exists in high quantities in certain foods (e.g. grapes and nuts). However, the capacity of RSV to…”
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A targeted approach for evaluating preclinical activity of botanical extracts for support of bone health by Lin, Yumei, Murray, Mary A., Garrett, I. Ross, Gutierrez, Gloria E., Nyman, Jeffry S., Mundy, Gregory, Fast, David, Gellenbeck, Kevin W., Chandra, Amitabh, Ramakrishnan, Shyam

“…Using a sequential in vitro/in vivo approach, we tested the ability of botanical extracts to influence biomarkers associated with bone resorption and bone…”
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Towards a Treatment for Gulf War Illness: A Consensus Docking Approach by Jaundoo, Rajeev, Bohmann, Jonathan, Gutierrez, Gloria E, Klimas, Nancy, Broderick, Gordon, Craddock, Travis J A

“…Abstract Introduction Gulf War Illness (GWI) currently has no known cure and affects soldiers deployed during the Persian Gulf War. It is thought to originate…”
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Local application of a proteasome inhibitor enhances fracture healing in rats by Yoshii, Toshitaka, Nyman, Jeffry S., Yuasa, Masato, Esparza, Javier M., Okawa, Atsushi, Gutierrez, Gloria E.

“…ABSTRACT The ubiquitin/proteasome system plays an important role in regulating the activity of osteoblast precursor cells. Proteasome inhibitors (PSIs) have…”
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Surface plasmon resonance (SPR) confirms that MEPE binds to PHEX via the MEPE–ASARM motif: a model for impaired mineralization in X-linked rickets (HYP) by Rowe, Peter S.N., Garrett, Ian R., Schwarz, Patricia M., Carnes, David L., Lafer, Eileen M., Mundy, Gregory R., Gutierrez, Gloria E.

“…Matrix Extracellular Phospho-glycoprotEin (MEPE) and proteases are elevated and PHEX is defective in HYP. PHEX prevents proteolysis of MEPE and release of a…”
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Enhanced expression of BMP2/Smad pathway and SP7 by statins during fracture repair by Gutierrez, Gloria E, Zhang, Jianghong, Jadhav, Satyawan, Steve, Munoz A, Mundy, Gregory R

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Red yeast rice stimulates bone formation in rats by Gutierrez, Gloria E., Mundy, Benjamin, Rossini, Gianni, Garrett, I. Ross, Chen, Stephen T., Mundy, Gregory R.

“…Statins are a class of drugs commonly prescribed to decrease cholesterol levels that have recently been shown to also stimulate bone formation. Clinical data…”
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The [omega]-3 fatty acid [alpha]-linolenic acid extends Caenorhabditis elegans lifespan via NHR-49/PPAR[alpha] and oxidation to oxylipins by Qi, Wenbo, Gutierrez, Gloria E, Gao, Xiaoli, Dixon, Hong, McDonough, Joe A, Marini, Ann M, Fisher, Alfred L

“…Summary The dietary intake of [omega]-3 polyunsaturated fatty acids has been linked to a reduction in the incidence of aging-associated disease including…”
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Transforming growth factor beta enhances parathyroid hormone stimulation of adenylate cyclase in clonal osteoblast-like cells by Gutierrez, G E, Mundy, G R, Manning, D R, Hewlett, E L, Katz, M S

“…The effects of transforming growth factor beta (TGF beta) on parathyroid hormone (PTH)-responsive adenylate cyclase were examined in clonal rat osteosarcoma…”
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A noncyclical analog of salmon calcitonin (N alpha-propionyl Di-Ala1,7,des-Leu19 sCT) retains full potency without inducing anorexia in rats by Yates, A J, Gutierrez, G E, Garrett, I R, Mencel, J J, Nuss, G W, Schreiber, A B, Mundy, G R

“…A new analog of salmon calcitonin (N alpha-propionyl Di-Ala1,7,des-Leu19 sCT; RG-12851; here termed CTR), which lacks the ring structure of native calcitonin,…”
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Alterations in hormone‐sensitive adenylate cyclase of cloned rat osteosarcoma cells during long‐term culture by Gutierrez, Gloria E., Mundy, Gregory R., Katz, Michael S.

“…The hormone‐sensitive adenylate cyclase system of a cloned bone cell line (UMR‐106) derived from a rat osteosarcoma was compared in preparations from cells of…”
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Adenylate cyclase of osteoblast-like cells from rat osteosarcoma is stimulated by calcitonin as well as parathyroid hormone by Gutierrez, G E, Mundy, G R, Katz, M S

“…Isolated bone cells are often described according to the presence of PTH- and calcitonin (CT)-sensitive adenylate cyclase activities. Osteoblasts are thought…”
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