Search Results - "Gutierrez, Erik"
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Cytosolic Quality Control of Mislocalized Proteins Requires RNF126 Recruitment to Bag6
Published in Molecular cell (17-07-2014)“…Approximately 30% of eukaryotic proteins contain hydrophobic signals for localization to the secretory pathway. These proteins can be mislocalized in the…”
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The hypusine-containing translation factor eIF5A
Published in Critical reviews in biochemistry and molecular biology (01-09-2014)“…In addition to the small and large ribosomal subunits, aminoacyl-tRNAs, and an mRNA, cellular protein synthesis is dependent on translation factors. The…”
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How to engineer glucose oxidase for mediated electron transfer
Published in Biotechnology and bioengineering (01-10-2018)“…Glucose oxidase (GOx) is of high industrial interest for glucose sensing because of its high β‐d‐glucose specificity. The efficient and specific…”
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Amino acid substrates impose polyamine, eIF5A, or hypusine requirement for peptide synthesis
Published in Nucleic acids research (21-08-2017)“…Whereas ribosomes efficiently catalyze peptide bond synthesis by most amino acids, the imino acid proline is a poor substrate for protein synthesis. Previous…”
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A randomized intraindividual comparative study evaluating the effects of two ultrasound-assisted liposuction devices on the abdomen
Published in Journal of plastic, reconstructive & aesthetic surgery (01-07-2024)“…Ultrasound-assisted liposuction (UAL) has become popular because of its favorable outcomes in fat emulsification, blood loss reduction, and skin tightening…”
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Reengineered glucose oxidase for amperometric glucose determination in diabetes analytics
Published in Biosensors & bioelectronics (15-12-2013)“…Glucose oxidase is an oxidoreductase exhibiting a high β-d-glucose specificity and high stability which renders glucose oxidase well-suited for applications in…”
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Buffer system improves the removal of host cell protein impurities in monoclonal antibody purification
Published in Biotechnology and bioengineering (01-12-2024)“…Polysorbates (PS) are commonly used as stabilizers of biopharmaceuticals such as monoclonal antibodies (mAbs). However, they are prone to chemical and…”
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Cysteine in cell culture media induces acidic IgG1 species by disrupting the disulfide bond network
Published in Biotechnology and bioengineering (01-03-2021)“…A high degree of charge heterogeneity is an unfavorable phenomenon commonly observed for therapeutic monoclonal antibodies (mAbs). Removal of these impurities…”
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Descriptive Analysis of the Arterial Supply to the Auricle in Patients with Unilateral Microtia
Published in Plastic and reconstructive surgery. Global open (01-12-2017)“…BACKGROUND:Microtia is a congenital auricular deformity that occurs in 1:5,000–10,000 births. It can cause severe impairment to the patient’s self-esteem and…”
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Silver-pig skin nanocomposites and mesenchymal stem cells: suitable antibiofilm cellular dressings for wound healing
Published in Journal of nanobiotechnology (10-01-2018)“…Treatment of severe or chronic skin wounds is an important challenge facing medicine and a significant health care burden. Proper wound healing is often…”
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Burn vs. Referral Physicians' TBSA Estimation Errors: A Cross-Sectional Study at the National Burn Center
Published in Burns open : an international open access journal for burn injuries (01-11-2024)“…•Physicians in a referring service tend to overestimate the total body surface area.•Computed-based methods offer a more reliable approach to estimating burn…”
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Protein targeting and degradation are coupled for elimination of mislocalized proteins
Published in Nature (London) (21-07-2011)“…Removal of 'spare' proteins Membrane proteins that fail to be delivered to the endoplasmic reticulum must be rapidly degraded to avoid inappropriate…”
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eIF5A Promotes Translation of Polyproline Motifs
Published in Molecular cell (11-07-2013)“…Translation factor eIF5A, containing the unique amino acid hypusine, was originally shown to stimulate Met-puromycin synthesis, a model assay for peptide bond…”
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890-P: Ultraselective DYRK1A/B Inhibitors Mediated ß-Cell Proliferation and Insulin Production In Vitro and In Vivo
Published in Diabetes (New York, N.Y.) (01-06-2024)“…Introduction and Objective: Non-selective DYRK1A/B inhibitors have been reported to stimulate pancreatic β-cell proliferation and insulin production. However…”
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Towards maximum acceleration of monoclonal antibody development: Leveraging transposase-mediated cell line generation to enable GMP manufacturing within 3 months using a stable pool
Published in Journal of biotechnology (10-04-2022)“…In recent years, acceleration of development timelines has become a major focus within the biopharmaceutical industry to bring innovative therapies faster to…”
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Protein Targeting and Degradation Pathways are Coupled for Elimination of Mislocalized Proteins
Published in The FASEB journal (01-04-2011)“…A substantial proportion of the genome encodes membrane proteins that are delivered to the endoplasmic reticulum by dedicated targeting pathways. Membrane…”
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Chondrogenic Potential of Human Adipose-Derived Mesenchymal Stromal Cells in Steam Sterilized Gelatin/Chitosan/Polyvinyl Alcohol Hydrogels
Published in Polymers (29-09-2023)“…Cross-linked polymer blends from natural compounds, namely gelatin (Gel), chitosan (CS), and synthetic poly (vinyl alcohol) (PVA), have received increasing…”
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Un Estado del Arte: Las TIC como Herramienta de Apoyo para la Educación Superior en México Durante y Pospandemia de COVID-19 Erik Moreno Gutiérrez
Published in Xihmai (30-06-2024)“…El presente texto aborda el estado del arte acerca de la importancia de las Tecnologías de Información y Comunicación (TIC) en las Universidades de México…”
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Reverse circumcision foreskin advancement flap for reconstructing penile shaft skin defects in adults with burn injuries in the perineal region
Published in Journal of tissue viability (22-06-2024)“…Genital burns are rare injuries. Reconstruction of penile skin defects should consider cosmetic and functional outcomes. Skin grafts can develop scar…”
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