Search Results - "Gutierrez, Dario A"

Hematopoietic Kit Deficiency, rather than Lack of Mast Cells, Protects Mice from Obesity and Insulin Resistance by Gutierrez, Dario A., Muralidhar, Sathya, Feyerabend, Thorsten B., Herzig, Stephan, Rodewald, Hans-Reimer

“…Obesity, insulin resistance, and related pathologies are associated with immune-mediated chronic inflammation. Kit mutant mice are protected from diet-induced…”
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Of Mouse Models of Mast Cell Deficiency and Metabolic Syndrome by Feyerabend, Thorsten B., Gutierrez, Dario A., Rodewald, Hans-Reimer

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CCR2 deficiency leads to increased eosinophils, alternative macrophage activation, and type 2 cytokine expression in adipose tissue by Bolus, W. Reid, Gutierrez, Dario A., Kennedy, Arion J., Anderson‐Baucum, Emily K., Hasty, Alyssa H.

“…Altered eosinophil content identified in adipose tissue of CCR2‐deficient mice, associated with changes in macrophage polarization and type‐2 cytokine…”
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Impact of increased adipose tissue mass on inflammation, insulin resistance, and dyslipidemia by Gutierrez, Dario A., Puglisi, Michael J., Hasty, Alyssa H.

“…Obesity is associated with increased prevalence of metabolic disorders, such as inflammation, insulin resistance, and dyslipidemia, which can predispose an…”
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A Sting in the Tale of Th2 Immunity by Gutierrez, Dario A., Rodewald, Hans-Reimer

“…Allergies are widely considered misguided Th2 cell responses. In this issue, Palm et al. (2013) and Marichal et al. (2013) show that mice mount anti-venom Th2…”
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Mechanisms of diversity maintenance in dung beetle assemblages in a heterogeneous tropical landscape by Rivera, Jose D, Gómez, Benigno, Navarrete-Gutiérrez, Darío A, Ruíz-Montoya, Lorena, Delgado, Leonardo, Favila, Mario E

“…Anthropized landscapes play a crucial role in biodiversity conservation, as they encompass about 90% of the remaining tropical forest. Effective conservation…”
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Evaluating and supporting conservation action in agricultural landscapes of the Usumacinta River Basin by Vaca, Raúl A., Rodiles-Hernández, Rocío, Ochoa-Gaona, Susana, Taylor-Aquino, Nathaline E., Obregón-Viloria, Rafael, Díaz-García, Daniela A., Navarrete-Gutiérrez, Darío A.

“…There is increasing recognition that ecosystems and their services need to be managed at landscape scale and greater. The development of landscape-scale…”
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Aberrant accumulation of undifferentiated myeloid cells in the adipose tissue of CCR2-deficient mice delays improvements in insulin sensitivity by Gutierrez, Dario A, Kennedy, Arion, Orr, Jeb S, Anderson, Emily K, Webb, Corey D, Gerrald, William K, Hasty, Alyssa H

“…Mice with CCR2 deficiency are protected from insulin resistance but only after long periods of high-fat diet (HFD) feeding, despite the virtual absence of…”
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Distinct subsets of neutrophils crosstalk with cytokines and metabolites in patients with sepsis by Parthasarathy, Upasana, Kuang, Yi, Thakur, Gunjan, Hogan, John D., Wyche, Thomas P., Norton, James E., Killough, Jason R., Sana, Theodore R., Beakes, Caroline, Shyong, BaoJen, Zhang, Rena N., Gutierrez, Dario A., Filbin, Michael, Christiani, David C., Therien, Alex G., Woelk, Christopher H., White, Cory H., Martinelli, Roberta

“…Sepsis is a life-threatening condition caused by a dysregulated host response to infection. Despite continued efforts to understand the pathophysiology of…”
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Vaccine Hyporesponse Induced by Individual Antibiotic Treatment in Mice and Non-Human Primates Is Diminished upon Recovery of the Gut Microbiome by Swaminathan, Gokul, Citron, Michael, Xiao, Jianying, Norton, James E., Reens, Abigail L., Topçuoğlu, Begüm D., Maritz, Julia M., Lee, Keun-Joong, Freed, Daniel C., Weber, Teresa M., White, Cory H., Kadam, Mahika, Spofford, Erin, Bryant-Hall, Erin, Salituro, Gino, Kommineni, Sushma, Liang, Xue, Danilchanka, Olga, Fontenot, Jane A., Woelk, Christopher H., Gutierrez, Dario A., Hazuda, Daria J., Hannigan, Geoffrey D.

“…Emerging evidence demonstrates a connection between microbiome composition and suboptimal response to vaccines (vaccine hyporesponse). Harnessing the…”
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Primary Human Dendritic Cells and Whole-Blood Based Assays to Evaluate Immuno-Modulatory Properties of Heat-Killed Commensal Bacteria by Norton, Jr, James E, Kommineni, Sushma, Akrivoulis, Patricia, Gutierrez, Dario A, Hazuda, Daria J, Swaminathan, Gokul

“…There is mounting evidence that the microbiome plays a critical role in training and maturation of the host immune system. Pre-clinical and clinical studies…”
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Impact of macrophage inflammatory protein-1α deficiency on atherosclerotic lesion formation, hepatic steatosis, and adipose tissue expansion by Kennedy, Arion, Gruen, Marnie L, Gutierrez, Dario A, Surmi, Bonnie K, Orr, Jeb S, Webb, Corey D, Hasty, Alyssa H

“…Macrophage inflammatory protein-1α (CCL3) plays a well-known role in infectious and viral diseases; however, its contribution to atherosclerotic lesion…”
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Weight Cycling Increases T-Cell Accumulation in Adipose Tissue and Impairs Systemic Glucose Tolerance by ANDERSON, Emily K, GUTIERREZ, Dario A, KENNEDY, Arion, HASTY, Alyssa H

“…Obesity is one of the leading causes of morbidity in the U.S. Accumulation of proinflammatory immune cells in adipose tissue (AT) contributes to the…”
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Adipose tissue recruitment of leukocytes by Anderson, Emily K, Gutierrez, Dario A, Hasty, Alyssa H

“…In December of 2003, two seminal articles describing the presence of macrophages in obese adipose tissue were published. These adipose tissue macrophages…”
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Functional enhancement of mesothelin-targeted TRuC-T cells by a PD1-CD28 chimeric switch receptor by McCarthy, Derrick, Lofgren, Michael, Watt, Amy, Horton, Holly, Kieffer-Kwon, Philippe, Ding, Jian, Kobold, Sebastian, Baeuerle, Patrick A., Hofmeister, Robert, Gutierrez, Dario A., Tighe, Robert

“…T cells expressing a mesothelin (MSLN)-specific T cell receptor fusion construct (TRuC ® ), called TC-210, have demonstrated robust antitumor activity in…”
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Type 1 diabetes in NOD mice unaffected by mast cell deficiency by Gutierrez, Dario A, Fu, Wenxian, Schonefeldt, Susann, Feyerabend, Thorsten B, Ortiz-Lopez, Adriana, Lampi, Yulia, Liston, Adrian, Mathis, Diane, Rodewald, Hans-Reimer

“…Mast cells have been invoked as important players in immune responses associated with autoimmune diseases. Based on in vitro studies, or in vivo through the…”
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Spatial analysis, local people's perception and economic valuation of wetland ecosystem services in the Usumacinta floodplain, Southern Mexico by Camacho-Valdez, Vera, Saenz-Arroyo, Andrea, Ghermandi, Andrea, Navarrete-Gutiérrez, Dario A, Rodiles-Hernández, Rocío

“…The Usumacinta floodplain is an exceptional area for biodiversity with important ecosystem services for local people. The main objective of this paper was to…”
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Impaired insulin signaling in the B10.D2- Hc 0 H2 d H2 - T18 c /oSnJ mouse model of complement factor 5 deficiency by Peterson, Kristin R, Gutierrez, Dario A, Kikuchi, Takuya, Anderson-Baucum, Emily K, Winn, Nathan C, Shuey, Megan M, Bolus, William R, McGuinness, Owen P, Hasty, Alyssa H

“…Given the chemoattractant potential of complement factor 5 (C5) and its increased expression in adipose tissue (AT) of obese mice, we determined whether this…”
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What Have We Really Learned About Macrophage Recruitment to Adipose Tissue? by Hasty, Alyssa H, Gutierrez, Dario A

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Haematopoietic leptin receptor deficiency does not affect macrophage accumulation in adipose tissue or systemic insulin sensitivity by Gutierrez, Dario A, Hasty, Alyssa H

“…The adipokine leptin is primarily produced by white adipose tissue (AT) and is a potent monocyte/macrophage chemoattractant in vitro. The long form of the…”
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