Search Results - "Guthrie, R W"

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  1. 1

    N-Benzylpyroglutamyl-L-phenylalanine derivatives as VCAM/VLA-4 antagonists by LI CHEN, TILLEY, J. W, WOLITZKY, B, ROWAN, K, GUTHRIE, R. W, MENNONA, F, HUANG, T.-N, KAPLAN, G, TRILLES, R, MIKLOWSKI, D, HUBY, N, SCHWINGE, V

    Published in Bioorganic & medicinal chemistry letters (17-04-2000)
    “…A series of N-(N-benzylpyroglutamyl)-4-substituted-L-phenylalanine derivatives was prepared as VLA-4/VCAM antagonists. Analogues substituted by electron…”
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    Journal Article
  2. 2

    N-Acyl phenylalanine analogues as potent small molecule VLA-4 antagonists by LI CHEN, TILLEY, J. W, WOLITZKY, B, HUANG, T.-N, MIKLOWSKI, D, TRILLES, R, GUTHRIE, R. W, KIN LUK, HANGLOW, A, ROWAN, K, SCHWINGE, V

    Published in Bioorganic & medicinal chemistry letters (17-04-2000)
    “…We have identified a series of low molecular weight (Mr < 500) N-acylphenylalanines that are effective inhibitors of the VCAM-VLA-4 interaction. Investigation…”
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    Journal Article
  3. 3

    Pentadienyl carboxamide derivatives as antagonists of platelet activating factor by Guthrie, Robert W, Kaplan, Gerald L, Mennona, Francis A, Tilley, Jefferson W, Kierstead, Richard W, Mullin, John G, LeMahieu, Ronald A, Zawoiski, Sonja, O'Donnell, Margaret

    Published in Journal of medicinal chemistry (01-08-1989)
    “…A series of N-[4-(3-pyridinyl)butyl]-5,5-disubstituted-pentadienamides was prepared and evaluated for PAF-antagonist activity. Compounds were assayed in vitro…”
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  4. 4

    Propenyl carboxamide derivatives as antagonists of platelet-activating factor by Guthrie, Robert W, Kaplan, Gerald L, Mennona, Francis A, Tilley, Jefferson W, Kierstead, Richard W, O'Donnell, Margaret, Crowley, Herman, Yaremko, Bohdan, Welton, Ann F

    Published in Journal of medicinal chemistry (01-10-1990)
    “…A series of N-[4-(3-pyridinyl)butyl] 3-substituted propenyl carboxamide derivatives bearing an unsaturated bicyclic moiety in the 3-position was prepared and…”
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    Journal Article
  5. 5

    Vocational Maturity and Its Relationship to Holland's Theory of Vocational Choice by Guthrie, W. R, Herman, Al

    Published in Journal of vocational behavior (01-10-1982)
    “…Studied the relationship of vocational maturity with Holland's theory of vocational choice. Examined Holland's constructs of consistency, differentiation, and…”
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    beta 1-selective adrenoceptor antagonists. 1. Synthesis and beta-adrenergic blocking activity of a series of binary (aryloxy)propanolamines by Kierstead, R W, Faraone, A, Mennona, F, Mullin, J, Guthrie, R W, Crowley, H, Simko, B, Blaber, L C

    Published in Journal of medicinal chemistry (01-11-1983)
    “…A series of binary (aryloxy)propanolamines has been prepared and examined in vitro and in vivo for beta-adrenoreceptor blocking activity. These symmetrical…”
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    Ellipticine derivatives by Guthrie, Robert W, Brossi, Arnold, Mennona, Francis A, Mullin, John G, Kierstead, Richard W, Grunberg, E

    Published in Journal of medicinal chemistry (01-07-1975)
    “…Several acyloxy and alkyl derivatives of ellipticine have been prepared. In addition, a modified synthesis leading to the hitherto unobtainable 8,9-dimethoxy-…”
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