Search Results - "Guthrie, Liam M"

Elesclomol alleviates Menkes pathology and mortality by escorting Cu to cuproenzymes in mice by Guthrie, Liam M, Soma, Shivatheja, Yuan, Sai, Silva, Andres, Zulkifli, Mohammad, Snavely, Thomas C, Greene, Hannah Faith, Nunez, Elyssa, Lynch, Brogan, De Ville, Courtney, Shanbhag, Vinit, Lopez, Franklin R, Acharya, Arjun, Petris, Michael J, Kim, Byung-Eun, Gohil, Vishal M, Sacchettini, James C

“…Loss-of-function mutations in the copper (Cu) transporter ATP7A cause Menkes disease. Menkes is an infantile, fatal, hereditary copper-deficiency disorder that…”
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Structure-Guided Drug Design of 6‑Substituted Adenosine Analogues as Potent Inhibitors of Mycobacterium tuberculosis Adenosine Kinase by Crespo, Roberto A, Dang, Qun, Zhou, Nian E, Guthrie, Liam M, Snavely, Thomas C, Dong, Wen, Loesch, Kimberly A, Suzuki, Takao, You, Lanying, Wang, Wei, O’Malley, Theresa, Parish, Tanya, Olsen, David B, Sacchettini, James C

“…Mycobacterium tuberculosis adenosine kinase (MtbAdoK) is an essential enzyme of Mtb and forms part of the purine salvage pathway within mycobacteria. Evidence…”
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Elesclomol Alleviates Menkes Pathology in Mice by Delivering Cu to Brain Cytochrome C Oxidase by Guthrie, Liam M

“…Copper is an essential micronutrient required for the proper biological function of numerous enzymes. Absorption, transportation, and elimination of copper is…”
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