Search Results - "Guthridge, Carla J."
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Serologic markers of Epstein-Barr virus reactivation are associated with increased disease activity, inflammation, and interferon pathway activation in patients with systemic lupus erythematosus
Published in Journal of translational autoimmunity (Online) (01-01-2021)“…SLE is a clinically heterogeneous disease characterized by an unpredictable relapsing-remitting disease course. Although the etiology and mechanisms of SLE…”
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INTERLEUKIN-1 RECEPTOR ANTAGONIST: Role in Biology
Published in Annual review of immunology (01-01-1998)“…The interleukin-1 receptor antagonist (IL-1Ra) is a member of the IL-1 family that binds to IL-1 receptors but does not induce any intracellular response. Two…”
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Ancestry-based differences in the immune phenotype are associated with lupus activity
Published in JCI insight (22-08-2023)“…Systemic lupus erythematosus (SLE) affects 1 in 537 Black women, which is >2-fold more than White women. Black patients develop the disease at a younger age,…”
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Expanded Autoantibody Profiles for Subsetting of Native American, African American, and European American Patients With Systemic Lupus Erythematosus
Published in ACR open rheumatology (01-07-2020)“…Objective Many Native American (NA) patients with systemic lupus erythematosus (SLE) do not exhibit the classical SLE autoantibody profiles of European…”
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Antibody Responses to Epstein‐Barr Virus in the Preclinical Period of Rheumatoid Arthritis Suggest the Presence of Increased Viral Reactivation Cycles
Published in Arthritis & rheumatology (Hoboken, N.J.) (01-04-2022)“…Objective Patients with established rheumatoid arthritis (RA) demonstrate altered immune responses to Epstein‐Barr virus (EBV), but the presence and roles of…”
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Unique Serum Immune Phenotypes and Stratification of Oklahoma Native American Rheumatic Disease Patients
Published in Arthritis care & research (2010) (01-04-2023)“…Objective Native American (NA) populations have higher rates of rheumatic disease and present with overlapping disease symptoms and nontraditional serologic…”
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Association of Autoantibody Concentrations and Trajectories With Lupus Nephritis Histologic Features and Treatment Response
Published in Arthritis & rheumatology (Hoboken, N.J.) (01-11-2024)“…Objective Autoantibodies are a hallmark of lupus nephritis (LN), but their association with LN classes and treatment response are not adequately known. In this…”
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Human monoclonal antibodies generated following vaccination with AVA provide neutralization by blocking furin cleavage but not by preventing oligomerization
Published in Vaccine (13-06-2012)“…Highlights ► We generated nine fully human monoclonal antibodies to anthrax protective antigen. ► Two antibodies were able to neutralize lethal toxin in vitro…”
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Unique clinical characteristics, autoantibodies and medication use in Native American patients with systemic lupus erythematosus
Published in Lupus science & medicine (2018)“…ObjectiveSystemic lupus erythematosus (SLE) is a systemic autoimmune disease with varied morbidity and mortality. We assessed clinical presentations,…”
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Unique serum immune phenotypes stratify Oklahoma Native American rheumatic disease patients
Published in Arthritis care & research (2010) (26-11-2022)Get full text
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Association of autoantibody concentrations and trajectories with lupus nephritis histological features and treatment response
Published in Arthritis & rheumatology (Hoboken, N.J.) (04-07-2024)“…Autoantibodies are a hallmark of lupus nephritis (LN), but their association with LN classes and treatment response are not adequately known. In this study, we…”
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Biological role of interleukin 1 receptor antagonist isoforms
Published in Annals of the rheumatic diseases (01-11-2000)“…The interleukin 1 receptor antagonist (IL1Ra) family of molecules now includes one secreted isoform (sIL1Ra) and three intracellular isoforms (icIL1Ra1, 2, and…”
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Biological role of interleukin 1 receptor antagonist isoforms
Published in Annals of the rheumatic diseases (01-11-2000)Get full text
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Lipopolysaccharide and Raf-1 kinase regulate secretory interleukin-1 receptor antagonist gene expression by mutually antagonistic mechanisms
Published in Molecular and Cellular Biology (01-03-1997)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Phospholipases A2 in ras-transformed and immortalized human mammary epithelial cells
Published in Cancer letters (28-10-1994)“…Phospholipase A2 (PLA2) activities of non-tumorigenic and tumorigenic human mammary epithelial cells, 184B5 cells (immortalized cell line from a reduction…”
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The effects of group II phospholipase A2 on ras-induced metastasis
Published in Advances in experimental medicine and biology (1997)Get more information
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