Search Results - "Guterman Ram, Gali"
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Dual‐specificity tyrosine phosphorylation‐regulated kinase 2 regulates osteoclast fusion in a cell heterotypic manner
Published in Journal of cellular physiology (01-01-2018)“…Monocyte fusion into osteoclasts, bone resorbing cells, plays a key role in bone remodeling and homeostasis; therefore, aberrant cell fusion may be involved in…”
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Placenta‐Derived Mesenchymal Stromal‐Like Cells Promote 3D‐Engineered Muscle Tissue Differentiation and Vessel Network Maturation
Published in Small science (01-11-2024)“…Placental‐derived stromal‐like cells (PLX‐PAD) have been shown to facilitate muscle tissue recovery after injury and stimulate angiogenesis. This work assesses…”
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Alterations of bone material properties in growing Ifitm5/BRIL p.S42 knock-in mice, a new model for atypical type VI osteogenesis imperfecta
Published in Bone (New York, N.Y.) (01-09-2022)“…Osteogenesis imperfecta (OI) is a heterogenous group of heritable connective tissue disorders characterized by high bone fragility due to low bone mass and…”
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Perturbed bone composition and integrity with disorganized osteoblast function in zinc receptor/Gpr39‐deficient mice
Published in The FASEB journal (01-05-2018)“…Changes in bone matrix composition are frequently found with bone diseases and maybe associated with increased fracture risk. Bone is rich in the trace element…”
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A dual-specific macrophage colony-stimulating factor antagonist of c-FMS and αvβ3 integrin for osteoporosis therapy
Published in PLoS biology (01-08-2018)“…There is currently a demand for new highly efficient and specific drugs to treat osteoporosis, a chronic bone disease affecting millions of people worldwide…”
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Atypical type VI Osteogenesis Imperfecta mouse models the intersection of IFITM5 and SERPINF1 pathways in patients
Published in Bone Reports (01-04-2021)Get full text
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New Ifitm5 S42L mouse model for atypical type VI OI connects types V and VI Osteogenesis Imperfecta
Published in Bone Reports (01-10-2020)Get full text
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Osteogenesis Imperfecta: Mechanisms and Signaling Pathways Connecting Classical and Rare OI Types
Published in Endocrine reviews (01-02-2022)“…Abstract Osteogenesis imperfecta (OI) is a phenotypically and genetically heterogeneous skeletal dysplasia characterized by bone fragility, growth deficiency,…”
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Osteoclast fusion is initiated by a small subset of RANKL-stimulated monocyte progenitors, which can fuse to RANKL-unstimulated progenitors
Published in Bone (New York, N.Y.) (01-10-2015)“…Abstract Osteoclasts are multinucleated, bone-resorbing cells formed via fusion of monocyte progenitors, a process triggered by prolonged stimulation with…”
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Pea Protein‐Rich Scaffolds Support 3D Bovine Skeletal Muscle Formation for Cultivated Meat Application
Published in Advanced sustainable systems (Online) (01-06-2024)“…In recent years, intensive efforts made to harness tissue engineering techniques to develop cultivated meat. Sustainable meat substitutes are a promising…”
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Schlafen2 mutation in mice causes an osteopetrotic phenotype due to a decrease in the number of osteoclast progenitors
Published in Scientific reports (29-08-2018)“…Osteoclasts are the bone resorbing cells that derive from myeloid progenitor cells. Although there have been recent advancements in the ability to identify…”
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A dual-specific macrophage colony-stimulating factor antagonist of c-FMS and [alpha].sub.v[beta].sub.3 integrin for osteoporosis therapy
Published in PLoS biology (24-08-2018)“…There is currently a demand for new highly efficient and specific drugs to treat osteoporosis, a chronic bone disease affecting millions of people worldwide…”
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Placenta‐Derived Mesenchymal Stromal‐Like Cells Promote 3D‐Engineered Muscle Tissue Differentiation and Vessel Network Maturation
Published in Small science (01-11-2024)“…Muscle Tissue Regeneration Research demonstrates that placenta‐derived stromal‐like cells (PLX‐PAD) enhance vascularization and maturation in engineered…”
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