Search Results - "Gustavo Jacob Lourenço"

The impact of ERP29 on the progression of pharyngeal squamous cell carcinoma by Carron, Juliana, Coser, Lilian de Oliveira, Lima, Carmen Silvia Passos, Lourenço, Gustavo Jacob

“…ERP29 gene encodes a chaperone protein critical for protein folding and secretion. Previous study linked ERP29 inhibition to an elevated risk of pharynx…”
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Association of Cytotoxic T-Lymphocyte Antigen-4 (CTLA-4) Genetic Variants with Risk and Outcome of Cutaneous Melanoma by Ferreira, Ana Maria Castro, Carron, Juliana, Gomez, Gabriela Vilas Bôas, Vazquez, Vinicius de Lima, Serrano, Sergio Vicente, Lourenço, Gustavo Jacob, Lima, Carmen Silvia Passos

“…This study aimed to verify whether germline single nucleotide variants (SNV) in CTLA-4 gene, c.-1765C>T, c.-1661A>G, c.-1577G>A, and c.-1478G>A, influence the…”
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Influence of variants in serotonin modulating genes on the risk, aggressiveness, and prognosis of oropharynx cancer by Queiroz, Gabriela Souza Rodrigues, Carron, Juliana, Macedo, Ligia Traldi, Lima, Carmen Silvia Passos, Lourenço, Gustavo Jacob

“…Background Serotonin (5‐HT) is involved in regulating tumor growth, as well as psychiatric disorders. It is synthesized by tryptophan hydroxylase (TPH) and…”
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Genetic variability in cisplatin metabolic pathways and outcome of locally advanced head and neck squamous cell carcinoma patients by Ferreira, Ana Maria Castro, Altemani, João Maurício Carrasco, Macedo, Ligia Traldi, Lourenço, Gustavo Jacob, Lima, Carmen Silvia Passos

“…Advanced head and neck squamous cell carcinoma (HNSCC) patients have been treated with cisplatin (CDDP) chemoradiation, and the variability of treatment…”
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Pseudogene Transcripts in Head and Neck Cancer: Literature Review and In Silico Analysis by Carron, Juliana, Della Coletta, Rafael, Lourenço, Gustavo Jacob

“…Once considered nonfunctional, pseudogene transcripts are now known to provide valuable information for cancer susceptibility, including head and neck cancer…”
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TNFRSF1B Gene Variants in Clinicopathological Aspects and Prognosis of Patients with Cutaneous Melanoma by Carvalho, Bruna Fernandes, Gomez, Gabriela Vilas Bôas, Carron, Juliana, Macedo, Ligia Traldi, Gonçalves, Gisele Melo, Vazquez, Vinicius de Lima, Serrano, Sergio Vicente, Lourenço, Gustavo Jacob, Lima, Carmen Silvia Passos

“…Regulatory T lymphocytes play a critical role in immune regulation and are involved in the aberrant cell elimination by facilitating tumor necrosis factor…”
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Implementation of a Psycho-oncology Service in a public hospital of Southeast Brazil: between politics and the COVID-19 pandemic by Pequeno, Daniel Paixão, Gaspar, Karla Cristina, Lima, Carmen Silvia Passos, Lourenço, Gustavo Jacob

“…Introduction: The implementation of a Psycho-oncology Service depends on institutional, structural, and political factors affecting the availability and…”
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Quality of life of family caregivers and survival of head and neck cancer patients in palliative care by Pequeno, Daniel Paixão, Carron, Juliana, Gaspar, Karla Cristina, Lima, Carmen Silvia Passos, Lourenço, Gustavo Jacob

“…Objective The aim of this study is to assess the effect of sociodemographic and genetic features on the quality of life (QoL) of family caregivers (FCGs) of…”
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IMPAIRMENT OF THE FUNCTIONAL CAPACITY OF PATIENTS WITH ADVANCED LUNG CANCER: A PROPOSAL FOR PRACTICING PHYSICAL EXERCISES AT HOME by Carmen Silvia Passos Lima, Joselaine Dantas, Luciana Campanatti Palhares, Gustavo Jacob Lourenço, Maurício Perroud Júnior

“…Introduction/Justification: Lung cancer (LC) is a disease with high incidence, morbidity, and mortality in Brazil and around the world. Smoking plays a…”
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CASP9 c.‐1339A>G and CASP3 c.‐1191A>G polymorphisms alter susceptibility and clinical aspects of head and neck squamous cell carcinoma by Costa, Ericka Francislaine Dias, Lopes‐Aguiar, Leisa, Nogueira, Guilherme Silva, Lima, Tathiane Regine Penna, Rinck‐Junior, José Augusto, Lourenço, Gustavo Jacob, Lima, Carmen Silvia Passos

“…Background Single nucleotide polymorphisms (SNPs) in genes that act in intrinsic apoptosis pathway may modulate cancer susceptibility. This study investigated…”
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Association of Inherited Copy Number Variation in ADAM3A and ADAM5 Pseudogenes with Oropharynx Cancer Risk and Outcome by Carron, Juliana, Torricelli, Caroline, Silva, Janet Keller, Liu, Yichuan, Pellegrino, Renata, Lima, Carmen Silvia Passos, Lourenço, Gustavo Jacob

“…Inherited copy number variations (CNVs) can provide valuable information for cancer susceptibility and prognosis. However, their association with oropharynx…”
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Influence of CASP9 c.‐1339A>G and CASP3 c.‐1191A>G variants in outcome of patients with head and neck squamous cell carcinoma by Carvalho, Bruna Fernandes, Costa, Ericka Francislaine Dias, Lopes‐Aguiar, Leisa, Liutti, Vitor Teixeira, Leal, Frederico, Vasconcelos, Vivian Castro Antunes, Rinck‐Junior, José Augusto, Lourenço, Gustavo Jacob, Lima, Carmen Silvia Passos

“…Background Abnormalities in the intrinsic apoptosis pathway, associated with single nucleotide variants (SNVs) in caspase (CASP) genes, alter head and neck…”
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GSTP1 and ABCB1 Polymorphisms Predicting Toxicities and Clinical Management on Carboplatin and Paclitaxel‐Based Chemotherapy in Ovarian Cancer by Ferracini, Amanda Canato, Lopes-Aguiar, Leisa, Lourenço, Gustavo Jacob, Yoshida, Adriana, Lima, Carmen Silva Passos, Sarian, Luis Otávio, Derchain, Sophie, Kroetz, Deanna L., Mazzola, Priscila Gava

“…Variation in drug disposition genes might contribute to susceptibility to toxicities and interindividual differences in clinical management on chemotherapy for…”
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The association of a single-nucleotide variant in the microRNA-146a with advanced colorectal cancer prognosis by Santos, Jéssica Silva dos, Zunta, Gabriella Lucatto, Negrini, Amanda Binatto, Ribeiro, Marina Silva Guinda, Martinez, Carlos Augusto Real, Ribeiro, Marcelo Lima, Lourenço, Gustavo Jacob, Ortega, Manoela Marques

“…The aim of this study was to evaluate the association of single-nucleotide variant n.60G>C (rs2910164) of microRNA (miR)-146a, related to suppressing of…”
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Association of Clinical Aspects and Genetic Variants with the Severity of Cisplatin-Induced Ototoxicity in Head and Neck Squamous Cell Carcinoma: A Prospective Cohort Study by Macedo, Ligia Traldi, Costa, Ericka Francislaine Dias, Carvalho, Bruna Fernandes, Lourenço, Gustavo Jacob, Calonga, Luciane, Castilho, Arthur Menino, Chone, Carlos Takahiro, Lima, Carmen Silvia Passos

“…Cisplatin (CDDP) is a major ototoxic chemotherapy agent for head and neck squamous cell carcinoma (HNSCC) treatment. Clinicopathological features and genotypes…”
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THYROID DYSFUNCTION IN HEAD AND NECK SQUAMOUS CELL CARCINOMA PATIENTS AFTER EXTERNAL RADIOTHERAPY by Carmen Silvia Passos Lima, Adriana Russo Fiore, Gustavo Jacob Lourenço, Eduardo Baldon Pereira, Luciana Freire de Almeida Anjos, Denise Engelbrecht Zantut-Wittmann

“…Introduction/Justification: Head and neck squamous cell carcinoma (HNSCC) is the seventh leading cause of cancer in the world, and substantial morbidity and…”
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TNFRSF1B GENE VARIANTS IN RISK AND CLINICOPATHOLOGICAL ASPECTS OF PATIENTS WITH CUTANEOUS MELANOMA by Matheus Yung Perin, Bruna Fernandes Carvalho, Gabriela Vilas Boas Gomez, Juliana Carron, Ligia Traldi Macedo, Gisele Melo Gonçalves, Vinicius de Lima Vazquez, Sergio Vicente Serrano, Gustavo Jacob Lourenço, Carmen Silvia Passos Lima

“…Introduction/Justification: Cutaneous melanoma (CM) is a low incidence tumor worldwide but is associated with high mortality. Skin exposure to ultraviolet…”
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Single nucleotide variants in immune-response genes and the tumor microenvironment composition predict progression of mantle cell lymphoma by Assis-Mendonça, Guilherme Rossi, Fattori, André, Rocha, Rafael Malagoli, Lourenço, Gustavo Jacob, Delamain, Márcia Torresan, Nonogaki, Suely, de Lima, Vladmir Cláudio Cordeiro, Colleoni, Gisele Wally Braga, de Souza, Cármino Antonio, Soares, Fernando Augusto, Lima, Carmen Silvia Passos, Vassallo, José

“…There is evidence to consider that the tumor microenvironment (TME) composition associates with antitumor immune response, and may predict the outcome of…”
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Cost-minimization analysis of GSTP1c.313A>G genotyping for the prevention of cisplatin-induced nausea and vomiting: A Bayesian inference approach by Macedo, Ligia Traldi, Ferrari, Vinicius Eduardo, Carron, Juliana, Costa, Ericka Francislaine Dias, Lopes-Aguiar, Leisa, Lourenço, Gustavo Jacob, Lima, Carmen Silvia Passos

“…Chemotherapy-induced nausea and vomiting are concerning adverse events resulting from cancer treatment, and current guidelines recommend the use of…”
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Influence of functional variants Asp312Asn and Lys751Gln of Xeroderma Pigmentosum Group D (XPD) and Glutathione S‐transferase Mu 1 (GSTM1) and Theta 1 (GSTT1) genes on cutaneous melanoma susceptibility and prognosis by Rinck‐Junior, José Augusto, Torricelli, Caroline, Gomez, Gabriela Vilas Bôas, Oliveira, Cristiane, Moraes, Aparecida Machado, Lourenço, Gustavo Jacob, Lima, Carmen Silvia Passos

“…We aimed to evaluate whether variants in repair (XPD Asp312Asn, XPD Lys751Gln) and detoxification (GSTM1, GSTT1) genes alter risk, clinicopathological aspects…”
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