Search Results - "Gustavo J. Silva"

Early cardiac-chamber-specific fingerprints in heart failure with preserved ejection fraction detected by FTIR and Raman spectroscopic techniques by Tombolesi, Niki, Altara, Raffaele, da Silva, Gustavo J. J., Tannous, Cynthia, Zouein, Fouad A., Stensløkken, Kåre-Olav, Morresi, Assunta, Paolantoni, Marco, Booz, George W., Cataliotti, Alessandro, Sassi, Paola

“…The pathophysiology of heart failure with preserved ejection fraction (HFpEF) is a matter of investigation and its diagnosis remains challenging. Although the…”
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A deep sequencing approach to uncover the miRNOME in the human heart by Leptidis, Stefanos, El Azzouzi, Hamid, Lok, Sjoukje I, de Weger, Roel, Olieslagers, Servé, Olieslagers, Serv, Kisters, Natasja, Silva, Gustavo J, Heymans, Stephane, Cuppen, Edwin, Berezikov, Eugene, De Windt, Leon J, da Costa Martins, Paula

“…MicroRNAs (miRNAs) are a class of non-coding RNAs of ∼22 nucleotides in length, and constitute a novel class of gene regulators by imperfect base-pairing to…”
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Nfat and miR-25 cooperate to reactivate the transcription factor Hand2 in heart failure by Dirkx, Ellen, Gladka, Monika M., Philippen, Leonne E., Armand, Anne-Sophie, Kinet, Virginie, Leptidis, Stefanos, el Azzouzi, Hamid, Salic, Kanita, Bourajjaj, Meriem, da Silva, Gustavo J. J., Olieslagers, Servé, van der Nagel, Roel, de Weger, Roel, Bitsch, Nicole, Kisters, Natasja, Seyen, Sandrine, Morikawa, Yuka, Chanoine, Christophe, Heymans, Stephane, Volders, Paul G. A., Thum, Thomas, Dimmeler, Stefanie, Cserjesi, Peter, Eschenhagen, Thomas, da Costa Martins, Paula A., De Windt, Leon J.

“…Although aberrant reactivation of embryonic gene programs is intricately linked to pathological heart disease, the transcription factors driving these gene…”
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Association between glutathione S-transferase polymorphisms and triglycerides and HDL-cholesterol by Maciel, Simone S, Pereira, Alexandre da C, Silva, Gustavo J.J, Rodrigues, Mariliza V, Mill, José G, Krieger, Jose E

“…Abstract Objective Null genotypes of glutathione S-transferase (GSTs) exhibit absence of enzymatic activity and are hypothesized to modulate an increased risk…”
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Preservation of cardiac function in left ventricle cardiac hypertrophy using an AAV vector which provides VEGF-A expression in response to p53 by Bajgelman, Marcio C, dos Santos, Leonardo, Silva, Gustavo J.J, Nakamuta, Juliana, Sirvente, Raquel A, Chaves, Marcio, Krieger, José Eduardo, Strauss, Bryan E

“…Abstract Here we present the application of our adeno-associated virus (AAV2) vector where transgene expression is driven by a synthetic, p53-responsive…”
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MicroRNAs as Important Regulators of Exercise Adaptation by Silva, Gustavo J.J., Bye, Anja, el Azzouzi, Hamid, Wisløff, Ulrik

“…A significant body of evidence supports the protective role of exercise training (ET) in cardiovascular diseases, skeletal muscle dystrophies, several types of…”
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Lack of UCP3 does not affect skeletal muscle mitochondrial function under lipid-challenged conditions, but leads to sudden cardiac death by Nabben, Miranda, van Bree, Bianca W. J., Lenaers, Ellen, Hoeks, Joris, Hesselink, Matthijs K. C., Schaart, Gert, Gijbels, Marion J. J., Glatz, Jan F. C., da Silva, Gustavo J. J., de Windt, Leon J., Tian, Rong, Mike, Elise, Skapura, Darlene G., Wehrens, Xander H. T., Schrauwen, Patrick

“…UCP3’s exact physiological function in lipid handling in skeletal and cardiac muscle remains unknown. Interestingly, etomoxir, a fat oxidation inhibitor and…”
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Diagnostic performance of microRNAs in the detection of heart failure with reduced or preserved ejection fraction: a systematic review and meta‐analysis by Parvan, Reza, Hosseinpour, Milad, Moradi, Yousef, Devaux, Yvan, Cataliotti, Alessandro, da Silva, Gustavo J.J.

“…Aim Chronic heart failure (CHF) can be classified as heart failure with preserved ejection fraction (HFpEF) or with reduced ejection fraction (HFrEF)…”
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Reversible pulmonary trunk banding. VI: Glucose-6-phosphate dehydrogenase activity in rapid ventricular hypertrophy in young goats by Assad, Renato S., MD, PhD, Atik, Fernando A., MD, Oliveira, Fernanda S, Fonseca-Alaniz, Miriam H., BPh, PhD, Abduch, Maria C.D., VMD, PhD, Silva, Gustavo J.J., PE, PhD, Favaro, Gustavo G., MD, Krieger, Jose E., MD, PhD, Stolf, Noedir A.G., MD, PhD

“…Objective Increased myocardial glucose-6-phosphate dehydrogenase (G6PD) activity occurs in heart failure. This study compared G6PD activity in 2 protocols of…”
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Circulating microRNAs predict future fatal myocardial infarction in healthy individuals – The HUNT study by Bye, Anja, Røsjø, Helge, Nauman, Javaid, Silva, Gustavo J.J, Follestad, Turid, Omland, Torbjørn, Wisløff, Ulrik

“…Abstract Coronary heart disease is the most common cause of death, and the number of individuals at risk is increasing. To better manage this pandemic,…”
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Etiology-Dependent Impairment of Diastolic Cardiomyocyte Calcium Homeostasis in Heart Failure With Preserved Ejection Fraction by Frisk, Michael, Le, Christopher, Shen, Xin, Røe, Åsmund T., Hou, Yufeng, Manfra, Ornella, Silva, Gustavo J.J., van Hout, Isabelle, Norden, Einar S., Aronsen, J. Magnus, Laasmaa, Martin, Espe, Emil K.S., Zouein, Fouad A., Lambert, Regis R., Dahl, Christen P., Sjaastad, Ivar, Lunde, Ida G., Coffey, Sean, Cataliotti, Alessandro, Gullestad, Lars, Tønnessen, Theis, Jones, Peter P., Altara, Raffaele, Louch, William E.

“…Whereas heart failure with reduced ejection fraction (HFrEF) is associated with ventricular dilation and markedly reduced systolic function, heart failure with…”
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Exercise training improves aortic depressor nerve sensitivity in rats with ischemia-induced heart failure by Rondon, Eduardo, Brasileiro-Santos, Maria S, Moreira, Edson D, Rondon, Maria U P B, Mattos, Katt C, Coelho, Marcele A, Silva, Gustavo J J, Brum, Patricia C, Fiorino, Patricia, Irigoyen, Maria C, Krieger, Eduardo M, Middlekauff, Holly R, Negrão, Carlos E

“…Exercise training improves arterial baroreflex control in heart failure (HF) rabbits. However, the mechanisms involved in the amelioration of baroreflex…”
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Heart failure with preserved ejection fraction induces molecular, mitochondrial, histological, and functional alterations in rat respiratory and limb skeletal muscle by Bowen, T. Scott, Rolim, Natale P. L., Fischer, Tina, Bækkerud, Fredrik H., Medeiros, Alessandra, Werner, Sarah, Brønstad, Eivind, Rognmo, Oivind, Mangner, Norman, Linke, Axel, Schuler, Gerhard, Silva, Gustavo J. J., Wisløff, Ulrik, Adams, Volker

“…Aims Peripheral muscle dysfunction is a key mechanism contributing to exercise intolerance (i.e. breathlessness and fatigue) in heart failure patients with…”
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Cardiac LXRα protects against pathological cardiac hypertrophy and dysfunction by enhancing glucose uptake and utilization by Cannon, Megan V, Silljé, Herman HW, Sijbesma, Jürgen WA, Vreeswijk‐Baudoin, Inge, Ciapaite, Jolita, van der Sluis, Bart, van Deursen, Jan, Silva, Gustavo JJ, de Windt, Leon J, Gustafsson, Jan‐Åke, van der Harst, Pim, van Gilst, Wiek H, de Boer, Rudolf A

“…Pathological cardiac hypertrophy is characterized by a shift in metabolic substrate utilization from fatty acids to glucose, but the molecular events…”
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Congenic strains provide evidence that four mapped loci in chromosomes 2, 4, and 16 influence hypertension in the SHR by Aneas, Ivy, Rodrigues, Mariliza V, Pauletti, Bianca A, Silva, Gustavo J. J, Carmona, Renata, Cardoso, Leandro, Kwitek, Anne E, Jacob, Howard J, Soler, Julia M. P, Krieger, Jose E

“…1 Heart Institute (InCor), University of São Paulo Medical School, São Paulo, SP, Brazil 2 Department of Statistics, Institute of Mathematics and Statistics,…”
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Effects of Sinoaortic Denervation on Hemodynamic Parameters During Natural Sleep in Rats by SILVEIRA, Neide P, MOREIRA, Edson D, DRAGER, Luciano F, SILVA, Gustavo J. J, KRIEGER, Eduardo M

“…To analyze the role of arterial baroreflex on hemodynamic changes during synchronized and desynchronized sleep phases of natural sleep in rats. Experimental…”
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Cardioprotective Effects of the Novel Compound Vastiras in a Preclinical Model of End-Organ Damage by Altara, Raffaele, da Silva, Gustavo J.J., Frisk, Michael, Spelta, Francesco, Zouein, Fouad A., Louch, William E., Booz, George W., Cataliotti, Alessandro

“…Cardiac hypertrophy and renal damage associated with hypertension are independent predictors of morbidity and mortality. In a model of hypertensive heart…”
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ACE gene dosage modulates pressure-induced cardiac hypertrophy in mice and men by Silva, Gustavo J. J, Moreira, Edson D, Pereira, Alexandre C, Mill, Jose G, Krieger, Eduardo M, Krieger, Jose E

“…1 Heart Institute (InCor), Department of Medicine-LIM13, University of São Paulo Medical School, São Paulo 2 Federal University of Espirito Santo, Vitoria,…”
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Cuff-induced vascular intima thickening is influenced by titration of the Ace gene in mice by Lacchini, Silvia, Heimann, Andrea S, Evangelista, Fabiana S, Cardoso, Leandro, Silva, Gustavo J. J, Krieger, Jose E

“…Heart Institute (InCor), University of São Paulo Medical School, São Paulo, SP, Brazil We tested the hypothesis that small changes in angiotensin I-converting…”
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Ace gene dosage influences the development of renovascular hypertension by Ceroni, Alexandre, Moreira, Edson D, Mostarda, Cristiano T, Silva, Gustavo JJ, Krieger, Eduardo M, Irigoyen, Maria C

“…Summary 1. Clinical and experimental evidence highlights the importance of the renin–angiotensin system in renovascular hypertension. Furthermore, genetic…”
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