Search Results - "Gustafson, E Hilary"

Guided self-organization and cortical plate formation in human brain organoids by Lancaster, Madeline A, Corsini, Nina S, Wolfinger, Simone, Gustafson, E Hilary, Phillips, Alex W, Burkard, Thomas R, Otani, Tomoki, Livesey, Frederick J, Knoblich, Juergen A

“…Engineering human brain organoids with floating scaffolds enhances the maturity and reproducibility of cortical tissue structure. Three-dimensional cell…”
Get full text

Shadow Enhancers Are Pervasive Features of Developmental Regulatory Networks by Cannavò, Enrico, Khoueiry, Pierre, Garfield, David A., Geeleher, Paul, Zichner, Thomas, Gustafson, E. Hilary, Ciglar, Lucia, Korbel, Jan O., Furlong, Eileen E.M.

“…Embryogenesis is remarkably robust to segregating mutations and environmental variation; under a range of conditions, embryos of a given species develop into…”
Get full text

Tissue-specific analysis of chromatin state identifies temporal signatures of enhancer activity during embryonic development by Bonn, Stefan, Zinzen, Robert P, Girardot, Charles, Gustafson, E Hilary, Perez-Gonzalez, Alexis, Delhomme, Nicolas, Ghavi-Helm, Yad, Wilczyński, Bartek, Riddell, Andrew, Furlong, Eileen E M

“…Eileen Furlong and colleagues report the development and application of BiTS-ChIP (batch isolate tissue specific chromatin immunoprecipitation), in which a…”
Get full text

A Transcription Factor Collective Defines Cardiac Cell Fate and Reflects Lineage History by Junion, Guillaume, Spivakov, Mikhail, Girardot, Charles, Braun, Martina, Gustafson, E. Hilary, Birney, Ewan, Furlong, Eileen E.M.

“…Cell fate decisions are driven through the integration of inductive signals and tissue-specific transcription factors (TFs), although the details on how this…”
Get full text

Uncoupling evolutionary changes in DNA sequence, transcription factor occupancy and enhancer activity by Khoueiry, Pierre, Girardot, Charles, Ciglar, Lucia, Peng, Pei-Chen, Gustafson, E Hilary, Sinha, Saurabh, Furlong, Eileen Em

“…Sequence variation within enhancers plays a major role in both evolution and disease, yet its functional impact on transcription factor (TF) occupancy and…”
Get full text

Model-based method for transcription factor target identification with limited data by Honkela, Antti, Girardot, Charles, Gustafson, E. Hilary, Liu, Ya-Hsin, Furlong, Eileen E.M, Lawrence, Neil D, Rattray, Magnus

“…We present a computational method for identifying potential targets of a transcription factor (TF) using wild-type gene expression time series data. For each…”
Get full text

Qualitative Dynamical Modelling Can Formally Explain Mesoderm Specification and Predict Novel Developmental Phenotypes by Mbodj, Abibatou, Gustafson, E Hilary, Ciglar, Lucia, Junion, Guillaume, Gonzalez, Aitor, Girardot, Charles, Perrin, Laurent, Furlong, Eileen E M, Thieffry, Denis

“…Given the complexity of developmental networks, it is often difficult to predict the effect of genetic perturbations, even within coding genes. Regulatory…”
Get full text

Combinatorial binding leads to diverse regulatory responses: Lmd is a tissue-specific modulator of Mef2 activity by Cunha, Paulo M F, Sandmann, Thomas, Gustafson, E Hilary, Ciglar, Lucia, Eichenlaub, Michael P, Furlong, Eileen E M

“…Understanding how complex patterns of temporal and spatial expression are regulated is central to deciphering genetic programs that drive development. Gene…”
Get full text

Temporal ChIP-on-chip reveals Biniou as a universal regulator of the visceral muscle transcriptional network by Jakobsen, Janus S, Braun, Martina, Astorga, Jeanette, Gustafson, E Hilary, Sandmann, Thomas, Karzynski, Michal, Carlsson, Peter, Furlong, Eileen E M

“…Smooth muscle plays a prominent role in many fundamental processes and diseases, yet our understanding of the transcriptional network regulating its…”
Get full text

Genetic variants regulating expression levels and isoform diversity during embryogenesis by Cannavò, Enrico, Koelling, Nils, Harnett, Dermot, Garfield, David, Casale, Francesco P., Ciglar, Lucia, Gustafson, Hilary E., Viales, Rebecca R., Marco-Ferreres, Raquel, Degner, Jacob F., Zhao, Bingqing, Stegle, Oliver, Birney, Ewan, Furlong, Eileen E. M.

“…The effects of genetic variation on transcriptional and post-transcriptional regulation are systematically mapped across multiple stages of embryogenesis in…”
Get full text

Publisher Correction: Guided self-organization and cortical plate formation in human brain organoids by Lancaster, Madeline A, Corsini, Nina S, Wolfinger, Simone, Gustafson, E Hilary, Phillips, Alex W, Burkard, Thomas R, Otani, Tomoki, Livesey, Frederick J, Knoblich, Juergen A

“…Nat. Biotechnol. 35, 659–666 (2017); published online 31 May 2017; corrected after print 14 August 2018 In the HTML and PDF versions of this article initially…”
Get full text

Erratum: Publisher Correction: Guided self-organization and cortical plate formation in human brain organoids by Lancaster, Madeline A, Corsini, Nina S, Wolfinger, Simone, Gustafson, E Hilary, Phillips, Alex W, Burkard, Thomas R, Otani, Tomoki, Livesey, Frederick J, Knoblich, Juergen A

Get full text

Combinatorial Binding Leads to Diverse Regulatory Responses: Lmd Is a Tissue-Specific Modulator of Mef2 Activity: e1001014 by Cunha, Paulo MF, Sandmann, Thomas, Gustafson, E Hilary, Ciglar, Lucia, Eichenlaub, Michael P, Furlong, Eileen EM

“…Understanding how complex patterns of temporal and spatial expression are regulated is central to deciphering genetic programs that drive development. Gene…”
Get full text

The C-terminal region of hPrp8 interacts with the conserved GU dinucleotide at the 5′ splice site by REYES, JOSÉ L., GUSTAFSON, E. HILARY, LUO, HONGBO R., MOORE, MELISSA J., KONARSKA, MARIA M.

“…A U5 snRNP protein, hPrp8, forms a UV-induced crosslink with the 5′ splice site (5′SS) RNA within splicing complex B assembled in trans- as well as in…”
Get full text

The 100-kDa U5 snRNP protein (hPrp28p) contacts the 5′ splice site through its ATPase site by ISMAÏLI, NAÏMA, SHA, MA, GUSTAFSON, E. HILARY, KONARSKA, MARIA M.

“…To identify splicing factors in proximity of the 5′ splice site (5′SS), we followed a crosslinking profile of site-specifically modified, photoreactive RNA…”
Get full text